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Hyalinizing spindle cell tumor with giant rosettes.

Ramaswamy AS, Chatura KR - Ann Saudi Med (2011 Jan-Feb)

Bottom Line: Recurrences are common, and late metastases have been recorded.Because of the similarities, both lesions are considered to be a single entity within the spectrum of low-grade sarcomas.Two cases of HSCTGR occurring in the lower limb are described in this report.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, People's Education Society Institute of Medical Sciences and Research, Kuppam, India.

ABSTRACT
Low-grade fibromyxoid sarcomas are uncommon deep-seated soft tissue neoplasms that exhibit a deceptively benign appearance microscopically. The finding of a linear or whorled array of spindled cells with few or no mitoses in a characteristic myxoid stroma can pose diagnostic dilemmas. Recurrences are common, and late metastases have been recorded. A closely related tumor, the so-called hyalinizing spindle cell tumor with giant collagen rosettes (HSCTGR), has also been described, with both the neoplasms having a similar cytogenetic abnormality and clinical behavior. Because of the similarities, both lesions are considered to be a single entity within the spectrum of low-grade sarcomas. Two cases of HSCTGR occurring in the lower limb are described in this report.

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Solid and gray-white mass with myxoid areas.
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Figure 0001: Solid and gray-white mass with myxoid areas.

Mentions: In the first case, the mass was globular and circumscribed, measuring 18×18×9 cm in gross appearance. On cut section, a central cystic area was seen that was filled with grayish-white friable tissue; this central area was bordered by a peripheral solid area. In the second case, the lesion measured 15×10×8 cm and was solid and gray-white, and had myxoid areas (Figure 1).


Hyalinizing spindle cell tumor with giant rosettes.

Ramaswamy AS, Chatura KR - Ann Saudi Med (2011 Jan-Feb)

Solid and gray-white mass with myxoid areas.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3101732&req=5

Figure 0001: Solid and gray-white mass with myxoid areas.
Mentions: In the first case, the mass was globular and circumscribed, measuring 18×18×9 cm in gross appearance. On cut section, a central cystic area was seen that was filled with grayish-white friable tissue; this central area was bordered by a peripheral solid area. In the second case, the lesion measured 15×10×8 cm and was solid and gray-white, and had myxoid areas (Figure 1).

Bottom Line: Recurrences are common, and late metastases have been recorded.Because of the similarities, both lesions are considered to be a single entity within the spectrum of low-grade sarcomas.Two cases of HSCTGR occurring in the lower limb are described in this report.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, People's Education Society Institute of Medical Sciences and Research, Kuppam, India.

ABSTRACT
Low-grade fibromyxoid sarcomas are uncommon deep-seated soft tissue neoplasms that exhibit a deceptively benign appearance microscopically. The finding of a linear or whorled array of spindled cells with few or no mitoses in a characteristic myxoid stroma can pose diagnostic dilemmas. Recurrences are common, and late metastases have been recorded. A closely related tumor, the so-called hyalinizing spindle cell tumor with giant collagen rosettes (HSCTGR), has also been described, with both the neoplasms having a similar cytogenetic abnormality and clinical behavior. Because of the similarities, both lesions are considered to be a single entity within the spectrum of low-grade sarcomas. Two cases of HSCTGR occurring in the lower limb are described in this report.

Show MeSH
Related in: MedlinePlus