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caGrid-Enabled caBIG Silver Level Compatible Head and Neck Cancer Tissue Database System.

Wang H, Bouzyk E, Kuehn A, Muller S, Chen Z, Khuri FR, Shin DM, Rogatko A, Tighiouart M - Open Med Inform J (2010)

Bottom Line: The system is implemented using a set of open source software and tools developed by the NCI, such as the caCORE SDK and caGrid.The head and neck cancer tissue database system has four interfaces: Web-based, Java API, XML utility, and Web service.The system has been shown to provide robust and programmatically accessible biomedical information services that syntactically and semantically interoperate with other resources.

View Article: PubMed Central - PubMed

Affiliation: Biostatistics Shared Core Resource, Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.

ABSTRACT
There are huge amounts of biomedical data generated by research labs in each cancer institution. The data are stored in various formats and accessed through numerous interfaces. It is very difficult to exchange and integrate the data among different cancer institutions, even among different research labs within the same institution, in order to discover useful biomedical knowledge for the healthcare community. In this paper, we present the design and implementation of a caGrid-enabled caBIG(TM) silver level compatible head and neck cancer tissue database system. The system is implemented using a set of open source software and tools developed by the NCI, such as the caCORE SDK and caGrid. The head and neck cancer tissue database system has four interfaces: Web-based, Java API, XML utility, and Web service. The system has been shown to provide robust and programmatically accessible biomedical information services that syntactically and semantically interoperate with other resources.

No MeSH data available.


Related in: MedlinePlus

A scatter plot of patient’s Intergrin Beta 1 value by his/her age in years.
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Figure 6: A scatter plot of patient’s Intergrin Beta 1 value by his/her age in years.

Mentions: Here we provide a successful application example of research project using our database. The project is to study the difference in a biomarker, Intergrin Beta 1, between non metastasis and metastasis patients. A dataset consisting of 101 metastasis and 106 non metastasis patients is collected using our database and exported by a user (Z. Chen). Some of analysis results with the dataset, such as a scatter plot of patient’s Intergrin Beat 1 by his/her age and a boxplot for comparison of Intergrin Beta 1 between non metastasis and metastasis patients, are shown in Figs. (6, 7), respectively.


caGrid-Enabled caBIG Silver Level Compatible Head and Neck Cancer Tissue Database System.

Wang H, Bouzyk E, Kuehn A, Muller S, Chen Z, Khuri FR, Shin DM, Rogatko A, Tighiouart M - Open Med Inform J (2010)

A scatter plot of patient’s Intergrin Beta 1 value by his/her age in years.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3095113&req=5

Figure 6: A scatter plot of patient’s Intergrin Beta 1 value by his/her age in years.
Mentions: Here we provide a successful application example of research project using our database. The project is to study the difference in a biomarker, Intergrin Beta 1, between non metastasis and metastasis patients. A dataset consisting of 101 metastasis and 106 non metastasis patients is collected using our database and exported by a user (Z. Chen). Some of analysis results with the dataset, such as a scatter plot of patient’s Intergrin Beat 1 by his/her age and a boxplot for comparison of Intergrin Beta 1 between non metastasis and metastasis patients, are shown in Figs. (6, 7), respectively.

Bottom Line: The system is implemented using a set of open source software and tools developed by the NCI, such as the caCORE SDK and caGrid.The head and neck cancer tissue database system has four interfaces: Web-based, Java API, XML utility, and Web service.The system has been shown to provide robust and programmatically accessible biomedical information services that syntactically and semantically interoperate with other resources.

View Article: PubMed Central - PubMed

Affiliation: Biostatistics Shared Core Resource, Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.

ABSTRACT
There are huge amounts of biomedical data generated by research labs in each cancer institution. The data are stored in various formats and accessed through numerous interfaces. It is very difficult to exchange and integrate the data among different cancer institutions, even among different research labs within the same institution, in order to discover useful biomedical knowledge for the healthcare community. In this paper, we present the design and implementation of a caGrid-enabled caBIG(TM) silver level compatible head and neck cancer tissue database system. The system is implemented using a set of open source software and tools developed by the NCI, such as the caCORE SDK and caGrid. The head and neck cancer tissue database system has four interfaces: Web-based, Java API, XML utility, and Web service. The system has been shown to provide robust and programmatically accessible biomedical information services that syntactically and semantically interoperate with other resources.

No MeSH data available.


Related in: MedlinePlus