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A case of metastatic mucoepidermoid carcinoma complicated by resistant hypercalcemia.

Popalzai MJ, Aoun N, Baz W, Mourad M, Forte F, Friscia P - Clin Med Insights Oncol (2011)

Bottom Line: Mucoepidermoid carcinoma is the most common malignant tumor of salivary glands, representing 5-10% of all salivary gland tumors.Histologic grade and the expression of various mucin glycoproteins are useful prognostic indicators.Also, this is the first reported case of humoral hypercalcemia of malignancy secondary to mucoepidermoid carcinoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, NY, 10305, USA.

ABSTRACT
Tumors of salivary glands are uncommon and comprise of about 2%-4% of all head and neck tumors. About 75%-80% of these tumors are benign and include pleomorphic adenoma, monomorphic adenoma, oncocytoma, and papillary cystadenoma lymphomatosum. Mucoepidermoid carcinoma is the most common malignant tumor of salivary glands, representing 5-10% of all salivary gland tumors. Although known to be metastatic to local lymph nodes, distant metastases are rare (especially, with low and intermediate grade tumors). Histologic grade and the expression of various mucin glycoproteins are useful prognostic indicators. We present a case of mucoepidermoid carcinoma of parotid gland origin with distant metastases which is an uncommon occurrence with intermediate grade tumors. Also, this is the first reported case of humoral hypercalcemia of malignancy secondary to mucoepidermoid carcinoma.

No MeSH data available.


Related in: MedlinePlus

MRI of the neck done on the initial presentation showing a 3 cm by 2.3 cm by 2.7 cm left parotid mass, involving the superficial and deep lobes of the left parotid gland.
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Related In: Results  -  Collection


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f1-cmo-2011-083: MRI of the neck done on the initial presentation showing a 3 cm by 2.3 cm by 2.7 cm left parotid mass, involving the superficial and deep lobes of the left parotid gland.


A case of metastatic mucoepidermoid carcinoma complicated by resistant hypercalcemia.

Popalzai MJ, Aoun N, Baz W, Mourad M, Forte F, Friscia P - Clin Med Insights Oncol (2011)

MRI of the neck done on the initial presentation showing a 3 cm by 2.3 cm by 2.7 cm left parotid mass, involving the superficial and deep lobes of the left parotid gland.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3095024&req=5

f1-cmo-2011-083: MRI of the neck done on the initial presentation showing a 3 cm by 2.3 cm by 2.7 cm left parotid mass, involving the superficial and deep lobes of the left parotid gland.
Bottom Line: Mucoepidermoid carcinoma is the most common malignant tumor of salivary glands, representing 5-10% of all salivary gland tumors.Histologic grade and the expression of various mucin glycoproteins are useful prognostic indicators.Also, this is the first reported case of humoral hypercalcemia of malignancy secondary to mucoepidermoid carcinoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, NY, 10305, USA.

ABSTRACT
Tumors of salivary glands are uncommon and comprise of about 2%-4% of all head and neck tumors. About 75%-80% of these tumors are benign and include pleomorphic adenoma, monomorphic adenoma, oncocytoma, and papillary cystadenoma lymphomatosum. Mucoepidermoid carcinoma is the most common malignant tumor of salivary glands, representing 5-10% of all salivary gland tumors. Although known to be metastatic to local lymph nodes, distant metastases are rare (especially, with low and intermediate grade tumors). Histologic grade and the expression of various mucin glycoproteins are useful prognostic indicators. We present a case of mucoepidermoid carcinoma of parotid gland origin with distant metastases which is an uncommon occurrence with intermediate grade tumors. Also, this is the first reported case of humoral hypercalcemia of malignancy secondary to mucoepidermoid carcinoma.

No MeSH data available.


Related in: MedlinePlus