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In vivo Spectrophotometric Assessment of the Tooth Whitening Effectiveness of Nite White 10% with Amorphous Calcium Phosphate, Potassium Nitrate and Fluoride, Over a 6-month Period.

Grobler SR, Majeed A, Moola MH, Rossouw RJ, van Wyk Kotze T - Open Dent J (2011)

Bottom Line: For all three components (L(*), a(*) and b(*)) statistical significant differences (p<0.05) in the values between base-line (pre-bleaching) and; after treatment, after 1-month, after 3-months as well as after 6-months were found (Wilcoxon Signed Rank Sum Test).However, no significant differences were found between pairs of ΔE(*) (ab) (0-1 month), ΔE(*) (ab) (0-3 months) and ΔE(*) (ab) (0-6months).The whitening effect decreased the most after one month and then maintained well even after a 6 month period (units 3.89).

View Article: PubMed Central - PubMed

Affiliation: Oral & Dental Research Institute, Faculty of Dentistry, Tygerberg, University of the Western Cape, Cape Town, South Africa.

ABSTRACT

Unlabelled: To clinically evaluate the effectiveness of Nite White 10% carbamide peroxide with amorphous calcium phosphate, potassium nitrate and fluoride over a 6-month follow-up period. Nite White was applied nightly for 14 days, according to the manufacturer's instructions. The color of teeth 11 and 21 of twenty one subjects was measured with a spectrophotometer (L(*); a(*); b(*)). Subjects were instructed to take note of any tooth sensitivity and gingival irritation. For all three components (L(*), a(*) and b(*)) statistical significant differences (p<0.05) in the values between base-line (pre-bleaching) and; after treatment, after 1-month, after 3-months as well as after 6-months were found (Wilcoxon Signed Rank Sum Test). Significant differences were also found amongst the ΔE(*) (ab) (0-14days) values and; ΔE(*) (ab) (0-1 month), ΔE*(ab) (0-3 months) and ΔE(*) (ab) (0-6 months). However, no significant differences were found between pairs of ΔE(*) (ab) (0-1 month), ΔE(*) (ab) (0-3 months) and ΔE(*) (ab) (0-6months). The decrease in ΔE(*) (ab) was the highest after 1 month (~30%). The highest decrease in L(*) was about 58% after 1 month. Over the 14-day treatment period tooth sensitivity was 24.5%.

Conclusions: Nite White ACP demonstrated significant tooth-whitening (unit increase = 5.29) with a low tooth sensitivity (25%) probably due to the presence of amorphous calcium phosphate, potassium nitrate, and fluoride. The whitening effect decreased the most after one month and then maintained well even after a 6 month period (units 3.89).

Clinical implications: The product is a good tooth whitener with a color increase of about 5 units accompanied with a low sensitivity.

No MeSH data available.


Related in: MedlinePlus

The 25 percentile, median and 75 percentile differences in the L* values between the base-line (before treatment) and after treatment (14 days), after 1-month, 3-months and after 6-months.
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Figure 1: The 25 percentile, median and 75 percentile differences in the L* values between the base-line (before treatment) and after treatment (14 days), after 1-month, 3-months and after 6-months.

Mentions: Before treatment (at base-line), no significant differences were found in all three different components (L*, a* and b*) between teeth 11 and 21 (Wilcoxon Signed Rank Sum Test). Therefore, the values for teeth 11 and 21 were subsequently pooled for any further analysis. For all three components (L*, a* and b*) statistical significant differences (p<0.05) in the values (Figs. 1-3) between base-line (pre-treatment), and after treatment (14 days later), after 1 month, after 3 months as well as after 6 months were found (Wilcoxon Signed Rank Sum Test). For all three components, significant differences (decrease) were found between just after treatment and 1 month, 3 months as well as after 6 months (Wilcoxon Signed Rank Sum Test). However, no significant differences were found in the median values of the three components amongst a 1-month, 3-months and 6-months period.


In vivo Spectrophotometric Assessment of the Tooth Whitening Effectiveness of Nite White 10% with Amorphous Calcium Phosphate, Potassium Nitrate and Fluoride, Over a 6-month Period.

Grobler SR, Majeed A, Moola MH, Rossouw RJ, van Wyk Kotze T - Open Dent J (2011)

The 25 percentile, median and 75 percentile differences in the L* values between the base-line (before treatment) and after treatment (14 days), after 1-month, 3-months and after 6-months.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3091384&req=5

Figure 1: The 25 percentile, median and 75 percentile differences in the L* values between the base-line (before treatment) and after treatment (14 days), after 1-month, 3-months and after 6-months.
Mentions: Before treatment (at base-line), no significant differences were found in all three different components (L*, a* and b*) between teeth 11 and 21 (Wilcoxon Signed Rank Sum Test). Therefore, the values for teeth 11 and 21 were subsequently pooled for any further analysis. For all three components (L*, a* and b*) statistical significant differences (p<0.05) in the values (Figs. 1-3) between base-line (pre-treatment), and after treatment (14 days later), after 1 month, after 3 months as well as after 6 months were found (Wilcoxon Signed Rank Sum Test). For all three components, significant differences (decrease) were found between just after treatment and 1 month, 3 months as well as after 6 months (Wilcoxon Signed Rank Sum Test). However, no significant differences were found in the median values of the three components amongst a 1-month, 3-months and 6-months period.

Bottom Line: For all three components (L(*), a(*) and b(*)) statistical significant differences (p<0.05) in the values between base-line (pre-bleaching) and; after treatment, after 1-month, after 3-months as well as after 6-months were found (Wilcoxon Signed Rank Sum Test).However, no significant differences were found between pairs of ΔE(*) (ab) (0-1 month), ΔE(*) (ab) (0-3 months) and ΔE(*) (ab) (0-6months).The whitening effect decreased the most after one month and then maintained well even after a 6 month period (units 3.89).

View Article: PubMed Central - PubMed

Affiliation: Oral & Dental Research Institute, Faculty of Dentistry, Tygerberg, University of the Western Cape, Cape Town, South Africa.

ABSTRACT

Unlabelled: To clinically evaluate the effectiveness of Nite White 10% carbamide peroxide with amorphous calcium phosphate, potassium nitrate and fluoride over a 6-month follow-up period. Nite White was applied nightly for 14 days, according to the manufacturer's instructions. The color of teeth 11 and 21 of twenty one subjects was measured with a spectrophotometer (L(*); a(*); b(*)). Subjects were instructed to take note of any tooth sensitivity and gingival irritation. For all three components (L(*), a(*) and b(*)) statistical significant differences (p<0.05) in the values between base-line (pre-bleaching) and; after treatment, after 1-month, after 3-months as well as after 6-months were found (Wilcoxon Signed Rank Sum Test). Significant differences were also found amongst the ΔE(*) (ab) (0-14days) values and; ΔE(*) (ab) (0-1 month), ΔE*(ab) (0-3 months) and ΔE(*) (ab) (0-6 months). However, no significant differences were found between pairs of ΔE(*) (ab) (0-1 month), ΔE(*) (ab) (0-3 months) and ΔE(*) (ab) (0-6months). The decrease in ΔE(*) (ab) was the highest after 1 month (~30%). The highest decrease in L(*) was about 58% after 1 month. Over the 14-day treatment period tooth sensitivity was 24.5%.

Conclusions: Nite White ACP demonstrated significant tooth-whitening (unit increase = 5.29) with a low tooth sensitivity (25%) probably due to the presence of amorphous calcium phosphate, potassium nitrate, and fluoride. The whitening effect decreased the most after one month and then maintained well even after a 6 month period (units 3.89).

Clinical implications: The product is a good tooth whitener with a color increase of about 5 units accompanied with a low sensitivity.

No MeSH data available.


Related in: MedlinePlus