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Primary sclerosing lipogranuloma: an unusual scrotal mass.

Singam P, Suriyani L, Ho C, Eng Hong G, Zainuddin Z - Libyan J Med (2010)

Bottom Line: The underlying pathological process is a granulomatous reaction of fatty tissue in this area.We present the case of a 40-year-old man with primary SLG of the external genitalia.Literature review on the treatment strategies are addressed and discussed.

View Article: PubMed Central - PubMed

Affiliation: Universiti Kebangsaan Malaysia Medical Center, Bandar Tun Razak, Kuala Lumpur, Cheras, Malaysia.

ABSTRACT
Sclerosing lipogranuloma (SLG) of the male external genitalia is a rare benign condition presenting as subcutaneous masses. The underlying pathological process is a granulomatous reaction of fatty tissue in this area. The cause of this is unclear but hypothesis stems around the pathogenesis of exogenous lipid degeneration from injection of foreign bodies such as paraffin for penile augmentation. However, endogenous lipid degeneration from other various causes such as infection, trauma, and allergic mechanisms has also been reported. We present the case of a 40-year-old man with primary SLG of the external genitalia. Literature review on the treatment strategies are addressed and discussed.

No MeSH data available.


Related in: MedlinePlus

Computer tomography appearance of suprapubic lipogranuloma. A – suprapubic fatty accumulation. B – left inguinal lymph node involvement.
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Figure 0002: Computer tomography appearance of suprapubic lipogranuloma. A – suprapubic fatty accumulation. B – left inguinal lymph node involvement.

Mentions: His white cell counts were 11.8×109 and erythrocyte sedimentation rate (ESR) was 79 mm/h. Urine full examination and microscopic examination (FEME) was normal. Ultrasonography showed thickened scrotum due to oedema, minimal hydrocele with normal testes. Blood screen for sexually transmitted diseases were negative. Serology test for tuberculosis, fungal, cytomegalovirus, and filariasis from blood and tissue cytology were negative. Computer tomography of abdomen and pelvis showed bilateral scrotal enlargement with presence of a fat component within, extending superiorly to anterior abdominal wall (Fig. 2). Initial fine needle aspiration of enlarged lymph node yield a mixed population of lymphoid cells, predominantly of small lymphocytes, suggestive of a reactive process. As this diagnosis was inadequate, an excision of lymph node was performed.


Primary sclerosing lipogranuloma: an unusual scrotal mass.

Singam P, Suriyani L, Ho C, Eng Hong G, Zainuddin Z - Libyan J Med (2010)

Computer tomography appearance of suprapubic lipogranuloma. A – suprapubic fatty accumulation. B – left inguinal lymph node involvement.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3066767&req=5

Figure 0002: Computer tomography appearance of suprapubic lipogranuloma. A – suprapubic fatty accumulation. B – left inguinal lymph node involvement.
Mentions: His white cell counts were 11.8×109 and erythrocyte sedimentation rate (ESR) was 79 mm/h. Urine full examination and microscopic examination (FEME) was normal. Ultrasonography showed thickened scrotum due to oedema, minimal hydrocele with normal testes. Blood screen for sexually transmitted diseases were negative. Serology test for tuberculosis, fungal, cytomegalovirus, and filariasis from blood and tissue cytology were negative. Computer tomography of abdomen and pelvis showed bilateral scrotal enlargement with presence of a fat component within, extending superiorly to anterior abdominal wall (Fig. 2). Initial fine needle aspiration of enlarged lymph node yield a mixed population of lymphoid cells, predominantly of small lymphocytes, suggestive of a reactive process. As this diagnosis was inadequate, an excision of lymph node was performed.

Bottom Line: The underlying pathological process is a granulomatous reaction of fatty tissue in this area.We present the case of a 40-year-old man with primary SLG of the external genitalia.Literature review on the treatment strategies are addressed and discussed.

View Article: PubMed Central - PubMed

Affiliation: Universiti Kebangsaan Malaysia Medical Center, Bandar Tun Razak, Kuala Lumpur, Cheras, Malaysia.

ABSTRACT
Sclerosing lipogranuloma (SLG) of the male external genitalia is a rare benign condition presenting as subcutaneous masses. The underlying pathological process is a granulomatous reaction of fatty tissue in this area. The cause of this is unclear but hypothesis stems around the pathogenesis of exogenous lipid degeneration from injection of foreign bodies such as paraffin for penile augmentation. However, endogenous lipid degeneration from other various causes such as infection, trauma, and allergic mechanisms has also been reported. We present the case of a 40-year-old man with primary SLG of the external genitalia. Literature review on the treatment strategies are addressed and discussed.

No MeSH data available.


Related in: MedlinePlus