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A rare cause of renal mass; a case study.

Elbarghati L, Azzouz L, Adiga K, Sallam S - Libyan J Med (2009)

Bottom Line: A seventy five year old gentleman with the clinical diagnosis of renal tuberculosis was found to have renal squamous cell carcinoma.The clinical presentation and management are being discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Medical School, Al Fateh University, Tripoli, Libya.

ABSTRACT
A seventy five year old gentleman with the clinical diagnosis of renal tuberculosis was found to have renal squamous cell carcinoma. The clinical presentation and management are being discussed.

No MeSH data available.


Related in: MedlinePlus

Partial nephrectomy specimen showing tumour in the upper pole.
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Figure 0002: Partial nephrectomy specimen showing tumour in the upper pole.

Mentions: Pathologically, the kidney was noted to have greyish white soft tissue mass, firm in consistency measuring 6x4x2 cms, with adjacent dilated calyces. The well circumscribed tumour appeared to be invading the calyses. Cut section revealed pink mass with foci of necrosis. The renal resection margin and external surface appeared free of tumour (Figure 2). Microscopically, the tumour consisted of pleomorphic squamoid cells arranged in nests and sheets with few foci of epithelial pearl formation and keratinisation. Areas of necrosis and frequent mitosis were noted. The malignant cells nore were seen to infiltrate the adjacent renal parenchyma as nests of cells and also focally renal capsule (Figures 3 & 4). The dilated calysis showed areas of squamous metaplasia and severe dysplasia with focal invasion of basement membrane into renal parenchyma to form the tumour (Figure 5). The renal tissue towards resection margin shows the features of chronic pyelonephritis. No granuloma was seen. The histological diagnosis of moderately differentiated squamous cell carcinoma was made.


A rare cause of renal mass; a case study.

Elbarghati L, Azzouz L, Adiga K, Sallam S - Libyan J Med (2009)

Partial nephrectomy specimen showing tumour in the upper pole.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3066746&req=5

Figure 0002: Partial nephrectomy specimen showing tumour in the upper pole.
Mentions: Pathologically, the kidney was noted to have greyish white soft tissue mass, firm in consistency measuring 6x4x2 cms, with adjacent dilated calyces. The well circumscribed tumour appeared to be invading the calyses. Cut section revealed pink mass with foci of necrosis. The renal resection margin and external surface appeared free of tumour (Figure 2). Microscopically, the tumour consisted of pleomorphic squamoid cells arranged in nests and sheets with few foci of epithelial pearl formation and keratinisation. Areas of necrosis and frequent mitosis were noted. The malignant cells nore were seen to infiltrate the adjacent renal parenchyma as nests of cells and also focally renal capsule (Figures 3 & 4). The dilated calysis showed areas of squamous metaplasia and severe dysplasia with focal invasion of basement membrane into renal parenchyma to form the tumour (Figure 5). The renal tissue towards resection margin shows the features of chronic pyelonephritis. No granuloma was seen. The histological diagnosis of moderately differentiated squamous cell carcinoma was made.

Bottom Line: A seventy five year old gentleman with the clinical diagnosis of renal tuberculosis was found to have renal squamous cell carcinoma.The clinical presentation and management are being discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, Medical School, Al Fateh University, Tripoli, Libya.

ABSTRACT
A seventy five year old gentleman with the clinical diagnosis of renal tuberculosis was found to have renal squamous cell carcinoma. The clinical presentation and management are being discussed.

No MeSH data available.


Related in: MedlinePlus