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Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships.

Garcia-Medina M, Garcia-Medina JJ, Garrido-Fernandez P, Galvan-Espinosa J, Martin-Molina J, Garcia-Maturana C, Perez-Pardo S, Pinazo-Duran MD - Clin Ophthalmol (2011)

Bottom Line: A linear relationship was found between CCT and IOP (R(2) = 0.152, P ≤ 0.001).However no linear relationship between DM and IOP, or between CCT and DM, was found.CCT was found to be similar to that reported in other studies in different populations.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Torrecardenas Hospital, Almeria, Spain;

ABSTRACT

Objective: To determine the values of, and study the relationships among, central corneal thickness (CCT), intraocular pressure (IOP), and degree of myopia (DM) in an adult myopic population aged 20 to 40 years in Almeria (southeast Spain). To our knowledge this is first study of this kind in this region.

Methods: An observational, descriptive, cross-sectional study was done in which a sample of 310 myopic patients (620 eyes) aged 20 to 40 years was selected by gender- and age-stratified sampling, which was proportionally fixed to the size of the population strata for which a 20% prevalence of myopia, 5% epsilon, and a 95% confidence interval were hypothesized. We studied IOP, CCT, and DM and their relationships by calculating the mean, standard deviation, 95% confidence interval for the mean, median, Fisher's asymmetry coefficient, range (maximum, minimum), and the Brown-Forsythe's robust test for each variable (IOP, CCT, and DM).

Results: In the adult myopic population of Almeria aged 20 to 40 years (mean of 29.8), the mean overall CCT was 550.12 μm. The corneas of men were thicker than those of women (P = 0.014). CCT was stable as no significant differences were seen in the 20- to 40-year-old subjects' CCT values. The mean overall IOP was 13.60 mmHg. Men had a higher IOP than women (P = 0.002). Subjects over 30 years (13.83) had a higher IOP than those under 30 (13.38) (P = 0.04). The mean overall DM was -4.18 diopters. Men had less myopia than women (P < 0.001). Myopia was stable in the 20- to 40-year-old study population (P = 0.089). A linear relationship was found between CCT and IOP (R(2) = 0.152, P ≤ 0.001). CCT influenced the IOP value by 15.2%. However no linear relationship between DM and IOP, or between CCT and DM, was found.

Conclusions: CCT was found to be similar to that reported in other studies in different populations. IOP tends to increase after the age of 30 and is not accounted for by alterations in CCT values.

No MeSH data available.


Related in: MedlinePlus

Comparison of myopia values between right and left eyes in the sample.
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f12-opth-5-249: Comparison of myopia values between right and left eyes in the sample.

Mentions: The overall mean in the right eyes was 4.17, with an SD of 2.51, a 95% CI of (3.89, 4.45), a range of 15 (minimum value of 1, maximum value of 16), an asymmetry coefficient of 1.29, and a median of 3.50. The overall mean of the left eyes was 4.19, with an SD of 2.54, a 95% CI of (3.91, 4.48), a range of 13.50 (minimum value of 1, maximum value of 14.50), an asymmetry coefficient of 1.29, and a median of 3.5. Our comparison shows no statistical significance (P = 0.759), although we cannot rule out the hypothesis of equality for the means found between the left and right eyes (Figure 12).


Central corneal thickness, intraocular pressure, and degree of myopia in an adult myopic population aged 20 to 40 years in southeast Spain: determination and relationships.

Garcia-Medina M, Garcia-Medina JJ, Garrido-Fernandez P, Galvan-Espinosa J, Martin-Molina J, Garcia-Maturana C, Perez-Pardo S, Pinazo-Duran MD - Clin Ophthalmol (2011)

Comparison of myopia values between right and left eyes in the sample.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3065564&req=5

f12-opth-5-249: Comparison of myopia values between right and left eyes in the sample.
Mentions: The overall mean in the right eyes was 4.17, with an SD of 2.51, a 95% CI of (3.89, 4.45), a range of 15 (minimum value of 1, maximum value of 16), an asymmetry coefficient of 1.29, and a median of 3.50. The overall mean of the left eyes was 4.19, with an SD of 2.54, a 95% CI of (3.91, 4.48), a range of 13.50 (minimum value of 1, maximum value of 14.50), an asymmetry coefficient of 1.29, and a median of 3.5. Our comparison shows no statistical significance (P = 0.759), although we cannot rule out the hypothesis of equality for the means found between the left and right eyes (Figure 12).

Bottom Line: A linear relationship was found between CCT and IOP (R(2) = 0.152, P ≤ 0.001).However no linear relationship between DM and IOP, or between CCT and DM, was found.CCT was found to be similar to that reported in other studies in different populations.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Torrecardenas Hospital, Almeria, Spain;

ABSTRACT

Objective: To determine the values of, and study the relationships among, central corneal thickness (CCT), intraocular pressure (IOP), and degree of myopia (DM) in an adult myopic population aged 20 to 40 years in Almeria (southeast Spain). To our knowledge this is first study of this kind in this region.

Methods: An observational, descriptive, cross-sectional study was done in which a sample of 310 myopic patients (620 eyes) aged 20 to 40 years was selected by gender- and age-stratified sampling, which was proportionally fixed to the size of the population strata for which a 20% prevalence of myopia, 5% epsilon, and a 95% confidence interval were hypothesized. We studied IOP, CCT, and DM and their relationships by calculating the mean, standard deviation, 95% confidence interval for the mean, median, Fisher's asymmetry coefficient, range (maximum, minimum), and the Brown-Forsythe's robust test for each variable (IOP, CCT, and DM).

Results: In the adult myopic population of Almeria aged 20 to 40 years (mean of 29.8), the mean overall CCT was 550.12 μm. The corneas of men were thicker than those of women (P = 0.014). CCT was stable as no significant differences were seen in the 20- to 40-year-old subjects' CCT values. The mean overall IOP was 13.60 mmHg. Men had a higher IOP than women (P = 0.002). Subjects over 30 years (13.83) had a higher IOP than those under 30 (13.38) (P = 0.04). The mean overall DM was -4.18 diopters. Men had less myopia than women (P < 0.001). Myopia was stable in the 20- to 40-year-old study population (P = 0.089). A linear relationship was found between CCT and IOP (R(2) = 0.152, P ≤ 0.001). CCT influenced the IOP value by 15.2%. However no linear relationship between DM and IOP, or between CCT and DM, was found.

Conclusions: CCT was found to be similar to that reported in other studies in different populations. IOP tends to increase after the age of 30 and is not accounted for by alterations in CCT values.

No MeSH data available.


Related in: MedlinePlus