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Evaluation of ability of dentifrices to remineralize artificial caries-like lesions.

Damle SG, Bengude V, Saini S - Dent Res J (Isfahan) (2010)

Bottom Line: The results were statistically analyzed using the student t test.P value less than 0.05 was considered significant.The average hardness recovery for the experimental group was significantly higher than that in the control group (P < 0.001).

View Article: PubMed Central - PubMed

Affiliation: Professor, Department of Pediatric Dentistry, M. M. College, Maharishi Markandeshwar University, Mullana, Ambala, India.

ABSTRACT

Background: Human endeavors to prevent dental caries have led to the use of different modalities and agents, the most commonly used of which is fluoridated dentifrice. An in situ study was carried out to evaluate the efficacy of fluoridated dentifrices in achieving remineralization of initial caries-like lesions using surface microhardness measurements and to study the qualitative changes by scan-ning electron microscopy.

Methods: Sixteen children 12-16 years of age wore a specially fabricated appliance with an artificially demineralized enamel slab for 24 hours a day, for four weeks. The children were divided into two groups, A and B. Following one week use of placebo dentifrice by both groups, group A used a fluoride dentifrice containing l000 ppm sodium monofluorophosphate, whereas group B used a placebo twice daily for 5 minutes for 21 days. Surface microhardness test carried out using a Knoop diamond indenter followed by scanning electron microscopy to evaluate the lesions. The results were statistically analyzed using the student t test. P value less than 0.05 was considered significant.

Results: The average hardness recovery for the experimental group was significantly higher than that in the control group (P < 0.001). Scanning electron microscopy revealed that fluoride significantly enhances remineralization of initial caries-like lesions.

Conclusion: Regular use of fluoridated dentifrices significantly enhances remineralization of white spot lesions.

No MeSH data available.


Related in: MedlinePlus

Photograph depicting demineralization and remineralization of enamel slabs (A) Demineralized enamel. (B) After fluoride dentifrice use. (C) After placebo dentifrice use.
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Figure 2: Photograph depicting demineralization and remineralization of enamel slabs (A) Demineralized enamel. (B) After fluoride dentifrice use. (C) After placebo dentifrice use.

Mentions: On observation under a scanning electron microscope, demineralized enamel slabs depicted features of demineralized zones similar to caries-like lesions. At 1000 magnification, deep pits in honeycomb pattern were observed (Figure 2A). After remineralization, the photomicrographs of group A revealed a more regular, smooth and homogenous surface. Discrete areas of crystallite formation were revealed (Figure 2B). Group B slabs revealed surface roughening however, some discrete zones of crystallite formation were observed (Figure 2C). The photomicrographs at 2000 magnification of the demineralized enamel slabs depicted microcavities which were created artificially and situated at different levels in the enamel. At 5000 magnification, numerous depressions in a honeycomb pattern were revealed.


Evaluation of ability of dentifrices to remineralize artificial caries-like lesions.

Damle SG, Bengude V, Saini S - Dent Res J (Isfahan) (2010)

Photograph depicting demineralization and remineralization of enamel slabs (A) Demineralized enamel. (B) After fluoride dentifrice use. (C) After placebo dentifrice use.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3065342&req=5

Figure 2: Photograph depicting demineralization and remineralization of enamel slabs (A) Demineralized enamel. (B) After fluoride dentifrice use. (C) After placebo dentifrice use.
Mentions: On observation under a scanning electron microscope, demineralized enamel slabs depicted features of demineralized zones similar to caries-like lesions. At 1000 magnification, deep pits in honeycomb pattern were observed (Figure 2A). After remineralization, the photomicrographs of group A revealed a more regular, smooth and homogenous surface. Discrete areas of crystallite formation were revealed (Figure 2B). Group B slabs revealed surface roughening however, some discrete zones of crystallite formation were observed (Figure 2C). The photomicrographs at 2000 magnification of the demineralized enamel slabs depicted microcavities which were created artificially and situated at different levels in the enamel. At 5000 magnification, numerous depressions in a honeycomb pattern were revealed.

Bottom Line: The results were statistically analyzed using the student t test.P value less than 0.05 was considered significant.The average hardness recovery for the experimental group was significantly higher than that in the control group (P < 0.001).

View Article: PubMed Central - PubMed

Affiliation: Professor, Department of Pediatric Dentistry, M. M. College, Maharishi Markandeshwar University, Mullana, Ambala, India.

ABSTRACT

Background: Human endeavors to prevent dental caries have led to the use of different modalities and agents, the most commonly used of which is fluoridated dentifrice. An in situ study was carried out to evaluate the efficacy of fluoridated dentifrices in achieving remineralization of initial caries-like lesions using surface microhardness measurements and to study the qualitative changes by scan-ning electron microscopy.

Methods: Sixteen children 12-16 years of age wore a specially fabricated appliance with an artificially demineralized enamel slab for 24 hours a day, for four weeks. The children were divided into two groups, A and B. Following one week use of placebo dentifrice by both groups, group A used a fluoride dentifrice containing l000 ppm sodium monofluorophosphate, whereas group B used a placebo twice daily for 5 minutes for 21 days. Surface microhardness test carried out using a Knoop diamond indenter followed by scanning electron microscopy to evaluate the lesions. The results were statistically analyzed using the student t test. P value less than 0.05 was considered significant.

Results: The average hardness recovery for the experimental group was significantly higher than that in the control group (P < 0.001). Scanning electron microscopy revealed that fluoride significantly enhances remineralization of initial caries-like lesions.

Conclusion: Regular use of fluoridated dentifrices significantly enhances remineralization of white spot lesions.

No MeSH data available.


Related in: MedlinePlus