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Combining information from surveys of several species to estimate the probability of freedom from Echinococcus multilocularis in Sweden, Finland and mainland Norway.

Wahlström H, Isomursu M, Hallgren G, Christensson D, Cedersmyg M, Wallensten A, Hjertqvist M, Davidson RK, Uhlhorn H, Hopp P - Acta Vet. Scand. (2011)

Bottom Line: Results from the model confirm that there is a high probability that in 2009 the countries were free from E. multilocularis.The sensitivity analyses showed that the choice of the design prevalences in different infected populations was influential.Therefore more knowledge on expected prevalences for E. multilocularis in infected populations of different species is desirable to reduce residual uncertainty of the results.

View Article: PubMed Central - HTML - PubMed

Affiliation: National Veterinary Institute, 752 89 Uppsala, Sweden. helene.wahlstrom@sva.se

ABSTRACT

Background: The fox tapeworm Echinococcus multilocularis has foxes and other canids as definitive host and rodents as intermediate hosts. However, most mammals can be accidental intermediate hosts and the larval stage may cause serious disease in humans. The parasite has never been detected in Sweden, Finland and mainland Norway. All three countries require currently an anthelminthic treatment for dogs and cats prior to entry in order to prevent introduction of the parasite. Documentation of freedom from E. multilocularis is necessary for justification of the present import requirements.

Methods: The probability that Sweden, Finland and mainland Norway were free from E. multilocularis and the sensitivity of the surveillance systems were estimated using scenario trees. Surveillance data from five animal species were included in the study: red fox (Vulpes vulpes), raccoon dog (Nyctereutes procyonoides), domestic pig, wild boar (Sus scrofa) and voles and lemmings (Arvicolinae).

Results: The cumulative probability of freedom from EM in December 2009 was high in all three countries, 0.98 (95% CI 0.96-0.99) in Finland and 0.99 (0.97-0.995) in Sweden and 0.98 (0.95-0.99) in Norway.

Conclusions: Results from the model confirm that there is a high probability that in 2009 the countries were free from E. multilocularis. The sensitivity analyses showed that the choice of the design prevalences in different infected populations was influential. Therefore more knowledge on expected prevalences for E. multilocularis in infected populations of different species is desirable to reduce residual uncertainty of the results.

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Life cycle of Echinococcus multilocularis.
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Figure 1: Life cycle of Echinococcus multilocularis.

Mentions: The fox tape worm Echinococcus multilocularis (EM) is a parasite of public health significance. The life cycle involves foxes and other canids as definitive hosts and rodents as intermediate hosts [1] although many other mammals species can be aberrant intermediate hosts (Figure 1). Humans become infected via the oral route, probably via contaminated hands after handling infected canids, contaminated plants or soil or through eating contaminated berries [1,2]. Human infection with EM can result in alveolar echinococcosis, a serious disease. If untreated the mortality exceeds 90% within 10 years, if treated the survival rate after five years increased to 88% [3].


Combining information from surveys of several species to estimate the probability of freedom from Echinococcus multilocularis in Sweden, Finland and mainland Norway.

Wahlström H, Isomursu M, Hallgren G, Christensson D, Cedersmyg M, Wallensten A, Hjertqvist M, Davidson RK, Uhlhorn H, Hopp P - Acta Vet. Scand. (2011)

Life cycle of Echinococcus multilocularis.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3049754&req=5

Figure 1: Life cycle of Echinococcus multilocularis.
Mentions: The fox tape worm Echinococcus multilocularis (EM) is a parasite of public health significance. The life cycle involves foxes and other canids as definitive hosts and rodents as intermediate hosts [1] although many other mammals species can be aberrant intermediate hosts (Figure 1). Humans become infected via the oral route, probably via contaminated hands after handling infected canids, contaminated plants or soil or through eating contaminated berries [1,2]. Human infection with EM can result in alveolar echinococcosis, a serious disease. If untreated the mortality exceeds 90% within 10 years, if treated the survival rate after five years increased to 88% [3].

Bottom Line: Results from the model confirm that there is a high probability that in 2009 the countries were free from E. multilocularis.The sensitivity analyses showed that the choice of the design prevalences in different infected populations was influential.Therefore more knowledge on expected prevalences for E. multilocularis in infected populations of different species is desirable to reduce residual uncertainty of the results.

View Article: PubMed Central - HTML - PubMed

Affiliation: National Veterinary Institute, 752 89 Uppsala, Sweden. helene.wahlstrom@sva.se

ABSTRACT

Background: The fox tapeworm Echinococcus multilocularis has foxes and other canids as definitive host and rodents as intermediate hosts. However, most mammals can be accidental intermediate hosts and the larval stage may cause serious disease in humans. The parasite has never been detected in Sweden, Finland and mainland Norway. All three countries require currently an anthelminthic treatment for dogs and cats prior to entry in order to prevent introduction of the parasite. Documentation of freedom from E. multilocularis is necessary for justification of the present import requirements.

Methods: The probability that Sweden, Finland and mainland Norway were free from E. multilocularis and the sensitivity of the surveillance systems were estimated using scenario trees. Surveillance data from five animal species were included in the study: red fox (Vulpes vulpes), raccoon dog (Nyctereutes procyonoides), domestic pig, wild boar (Sus scrofa) and voles and lemmings (Arvicolinae).

Results: The cumulative probability of freedom from EM in December 2009 was high in all three countries, 0.98 (95% CI 0.96-0.99) in Finland and 0.99 (0.97-0.995) in Sweden and 0.98 (0.95-0.99) in Norway.

Conclusions: Results from the model confirm that there is a high probability that in 2009 the countries were free from E. multilocularis. The sensitivity analyses showed that the choice of the design prevalences in different infected populations was influential. Therefore more knowledge on expected prevalences for E. multilocularis in infected populations of different species is desirable to reduce residual uncertainty of the results.

Show MeSH
Related in: MedlinePlus