Limits...
Neurologic manifestation as initial presentation in a case of hereditary haemorrhagic telangiectasia.

Teo YK, Kor AC - Clin Med Insights Case Rep (2010)

Bottom Line: Hereditary Haemorrhagic Telangiectasia (HHT), or Osler-Weber-Rendu syndrome is an uncommon autosomal dominant multi-organ condition of vascular dysplasias.We describe a 19 year old Indian female who presented with cerebral abscess secondary to paradoxical emboli from pulmonary arteriovenous malformations (PAVMs) associated with HHT.Cerebral, pulmonary, hepatic and gastrointestinal involvement can be life-threatening and it is important to have lifelong follow-ups on these patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.

ABSTRACT
Hereditary Haemorrhagic Telangiectasia (HHT), or Osler-Weber-Rendu syndrome is an uncommon autosomal dominant multi-organ condition of vascular dysplasias. We describe a 19 year old Indian female who presented with cerebral abscess secondary to paradoxical emboli from pulmonary arteriovenous malformations (PAVMs) associated with HHT. Cerebral, pulmonary, hepatic and gastrointestinal involvement can be life-threatening and it is important to have lifelong follow-ups on these patients.

No MeSH data available.


Related in: MedlinePlus

Transcather embolisation with a metallic coil (black arrow) into a PAVM (white arrow) located in the right lung.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC3046015&req=5

f4-ccrep-2010-015: Transcather embolisation with a metallic coil (black arrow) into a PAVM (white arrow) located in the right lung.

Mentions: Further investigations were performed to exclude AVMs in other sites of the body. MRI of the brain did not reveal any AVMs. CT liver did not reveal any AVMs. Transcatheter embolisation of the PAVMs was performed on 2 separate occasions. Left pulmonary angiogram (Fig. 4) showed 2 lower lobe PAVMs about 1 cm in diameter and multiple embolic coils inserted successfully. Right pulmonary angiogram revealed 4 PAVMs about 1 cm in diameter and embolisation of 3 lesions were done. One PAVM was inaccessible. She was followed up yearly to screen for new development of PAVMs and AVMs from other sites.


Neurologic manifestation as initial presentation in a case of hereditary haemorrhagic telangiectasia.

Teo YK, Kor AC - Clin Med Insights Case Rep (2010)

Transcather embolisation with a metallic coil (black arrow) into a PAVM (white arrow) located in the right lung.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3046015&req=5

f4-ccrep-2010-015: Transcather embolisation with a metallic coil (black arrow) into a PAVM (white arrow) located in the right lung.
Mentions: Further investigations were performed to exclude AVMs in other sites of the body. MRI of the brain did not reveal any AVMs. CT liver did not reveal any AVMs. Transcatheter embolisation of the PAVMs was performed on 2 separate occasions. Left pulmonary angiogram (Fig. 4) showed 2 lower lobe PAVMs about 1 cm in diameter and multiple embolic coils inserted successfully. Right pulmonary angiogram revealed 4 PAVMs about 1 cm in diameter and embolisation of 3 lesions were done. One PAVM was inaccessible. She was followed up yearly to screen for new development of PAVMs and AVMs from other sites.

Bottom Line: Hereditary Haemorrhagic Telangiectasia (HHT), or Osler-Weber-Rendu syndrome is an uncommon autosomal dominant multi-organ condition of vascular dysplasias.We describe a 19 year old Indian female who presented with cerebral abscess secondary to paradoxical emboli from pulmonary arteriovenous malformations (PAVMs) associated with HHT.Cerebral, pulmonary, hepatic and gastrointestinal involvement can be life-threatening and it is important to have lifelong follow-ups on these patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.

ABSTRACT
Hereditary Haemorrhagic Telangiectasia (HHT), or Osler-Weber-Rendu syndrome is an uncommon autosomal dominant multi-organ condition of vascular dysplasias. We describe a 19 year old Indian female who presented with cerebral abscess secondary to paradoxical emboli from pulmonary arteriovenous malformations (PAVMs) associated with HHT. Cerebral, pulmonary, hepatic and gastrointestinal involvement can be life-threatening and it is important to have lifelong follow-ups on these patients.

No MeSH data available.


Related in: MedlinePlus