Limits...
Neurologic manifestation as initial presentation in a case of hereditary haemorrhagic telangiectasia.

Teo YK, Kor AC - Clin Med Insights Case Rep (2010)

Bottom Line: Hereditary Haemorrhagic Telangiectasia (HHT), or Osler-Weber-Rendu syndrome is an uncommon autosomal dominant multi-organ condition of vascular dysplasias.We describe a 19 year old Indian female who presented with cerebral abscess secondary to paradoxical emboli from pulmonary arteriovenous malformations (PAVMs) associated with HHT.Cerebral, pulmonary, hepatic and gastrointestinal involvement can be life-threatening and it is important to have lifelong follow-ups on these patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.

ABSTRACT
Hereditary Haemorrhagic Telangiectasia (HHT), or Osler-Weber-Rendu syndrome is an uncommon autosomal dominant multi-organ condition of vascular dysplasias. We describe a 19 year old Indian female who presented with cerebral abscess secondary to paradoxical emboli from pulmonary arteriovenous malformations (PAVMs) associated with HHT. Cerebral, pulmonary, hepatic and gastrointestinal involvement can be life-threatening and it is important to have lifelong follow-ups on these patients.

No MeSH data available.


Related in: MedlinePlus

Shows a focal nodular appearance of pulmonary vessels (arrow), representing one of the arteriovenous malfomations in the right lung.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC3046015&req=5

f3-ccrep-2010-015: Shows a focal nodular appearance of pulmonary vessels (arrow), representing one of the arteriovenous malfomations in the right lung.

Mentions: Various investigations were performed to determine the source of the cerebral abscess. Dental review was normal, 2-dimensional trans-thoracic echocardiography did not show any infective endocarditis and otolaryngologist assessment was normal. While recovering in the general ward, the patient had an episode of oxygen desaturation. A CT pulmonary angiogram was done (Fig. 3) to look for pulmonary embolism which was absent. Instead, the scan revealed multiple PAVMs in both lungs. It was postulated that the PAVMs allow right-to-left shunting of paradoxical emboli, resulting in the cerebral abscess.


Neurologic manifestation as initial presentation in a case of hereditary haemorrhagic telangiectasia.

Teo YK, Kor AC - Clin Med Insights Case Rep (2010)

Shows a focal nodular appearance of pulmonary vessels (arrow), representing one of the arteriovenous malfomations in the right lung.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3046015&req=5

f3-ccrep-2010-015: Shows a focal nodular appearance of pulmonary vessels (arrow), representing one of the arteriovenous malfomations in the right lung.
Mentions: Various investigations were performed to determine the source of the cerebral abscess. Dental review was normal, 2-dimensional trans-thoracic echocardiography did not show any infective endocarditis and otolaryngologist assessment was normal. While recovering in the general ward, the patient had an episode of oxygen desaturation. A CT pulmonary angiogram was done (Fig. 3) to look for pulmonary embolism which was absent. Instead, the scan revealed multiple PAVMs in both lungs. It was postulated that the PAVMs allow right-to-left shunting of paradoxical emboli, resulting in the cerebral abscess.

Bottom Line: Hereditary Haemorrhagic Telangiectasia (HHT), or Osler-Weber-Rendu syndrome is an uncommon autosomal dominant multi-organ condition of vascular dysplasias.We describe a 19 year old Indian female who presented with cerebral abscess secondary to paradoxical emboli from pulmonary arteriovenous malformations (PAVMs) associated with HHT.Cerebral, pulmonary, hepatic and gastrointestinal involvement can be life-threatening and it is important to have lifelong follow-ups on these patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.

ABSTRACT
Hereditary Haemorrhagic Telangiectasia (HHT), or Osler-Weber-Rendu syndrome is an uncommon autosomal dominant multi-organ condition of vascular dysplasias. We describe a 19 year old Indian female who presented with cerebral abscess secondary to paradoxical emboli from pulmonary arteriovenous malformations (PAVMs) associated with HHT. Cerebral, pulmonary, hepatic and gastrointestinal involvement can be life-threatening and it is important to have lifelong follow-ups on these patients.

No MeSH data available.


Related in: MedlinePlus