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A case of rheumatoid arthritis with bucillamine-induced yellow nail syndrome initially manifesting as pulmonary disease.

Isozaki T, Yajima N, Sato M, Takahashi R, Wakabayashi K, Miwa Y, Negishi M, Ide H, Kasama T - Clin Med Insights Case Rep (2010)

Bottom Line: We report a case of a 67-year-old woman with rheumatoid arthritis with yellow nail syndrome (YNS) that was caused by bucillamine.All three signs (yellow fingernails, lymphatic edema, and bronchiectasis) of YNS manifested, with characteristic timing, first with the nails turning yellow after when bronchiectasis was noticed.We reviewed 10 case reports from Japan and compared the periods until the appearance of yellow nails after starting bucillamine treatment, as well as those until lung disease and leg edema appeared.

View Article: PubMed Central - PubMed

Affiliation: Division of Rheumatology, Department of Medicine, Showa University School of Medicine, Tokyo 142-8666, Japan.

ABSTRACT
We report a case of a 67-year-old woman with rheumatoid arthritis with yellow nail syndrome (YNS) that was caused by bucillamine. All three signs (yellow fingernails, lymphatic edema, and bronchiectasis) of YNS manifested, with characteristic timing, first with the nails turning yellow after when bronchiectasis was noticed. We reviewed 10 case reports from Japan and compared the periods until the appearance of yellow nails after starting bucillamine treatment, as well as those until lung disease and leg edema appeared.

No MeSH data available.


Related in: MedlinePlus

Appearance of nails. All of the patient’s nails were yellow. July 2004 (A), and February 2010 (B).
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f2-ccrep-2010-063: Appearance of nails. All of the patient’s nails were yellow. July 2004 (A), and February 2010 (B).

Mentions: The patient’s temperature was 35.1 °C, blood pressure 132/78 mmHg, and pulse 78 bpm. Her heart sounds were normal, but her breath sounds were decreased on the left. All of her nails were yellow (Fig. 2A). Nonpitting edema of both lower limbs was noted (Fig. 3A). There was no apparent swelling or tenderness of the joints.


A case of rheumatoid arthritis with bucillamine-induced yellow nail syndrome initially manifesting as pulmonary disease.

Isozaki T, Yajima N, Sato M, Takahashi R, Wakabayashi K, Miwa Y, Negishi M, Ide H, Kasama T - Clin Med Insights Case Rep (2010)

Appearance of nails. All of the patient’s nails were yellow. July 2004 (A), and February 2010 (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3046014&req=5

f2-ccrep-2010-063: Appearance of nails. All of the patient’s nails were yellow. July 2004 (A), and February 2010 (B).
Mentions: The patient’s temperature was 35.1 °C, blood pressure 132/78 mmHg, and pulse 78 bpm. Her heart sounds were normal, but her breath sounds were decreased on the left. All of her nails were yellow (Fig. 2A). Nonpitting edema of both lower limbs was noted (Fig. 3A). There was no apparent swelling or tenderness of the joints.

Bottom Line: We report a case of a 67-year-old woman with rheumatoid arthritis with yellow nail syndrome (YNS) that was caused by bucillamine.All three signs (yellow fingernails, lymphatic edema, and bronchiectasis) of YNS manifested, with characteristic timing, first with the nails turning yellow after when bronchiectasis was noticed.We reviewed 10 case reports from Japan and compared the periods until the appearance of yellow nails after starting bucillamine treatment, as well as those until lung disease and leg edema appeared.

View Article: PubMed Central - PubMed

Affiliation: Division of Rheumatology, Department of Medicine, Showa University School of Medicine, Tokyo 142-8666, Japan.

ABSTRACT
We report a case of a 67-year-old woman with rheumatoid arthritis with yellow nail syndrome (YNS) that was caused by bucillamine. All three signs (yellow fingernails, lymphatic edema, and bronchiectasis) of YNS manifested, with characteristic timing, first with the nails turning yellow after when bronchiectasis was noticed. We reviewed 10 case reports from Japan and compared the periods until the appearance of yellow nails after starting bucillamine treatment, as well as those until lung disease and leg edema appeared.

No MeSH data available.


Related in: MedlinePlus