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A Randomized, Prospective Study of the Treatment of Superficial Partial-Thickness Burns: AWBAT-S Versus Biobrane.

Greenwood JE - Eplasty (2011)

Bottom Line: The aim of this study was to prospectively evaluate AWBAT-S in comparison with Biobrane for the treatment of superficial partial-thickness burns using the patient as his or her own control.Primary outcome measures included length of hospital inpatient stay and patient-reported perception of pain.Secondary outcome measures included time to healing, clinical outcome of burn sites (scarring) and a comparison of cost of care for patients treated with AWBAT-S versus Biobrane.

View Article: PubMed Central - PubMed

Affiliation: Adult Burn Service, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia, Australia.

ABSTRACT
The aim of this study was to prospectively evaluate AWBAT-S in comparison with Biobrane for the treatment of superficial partial-thickness burns using the patient as his or her own control. Primary outcome measures included length of hospital inpatient stay and patient-reported perception of pain. Secondary outcome measures included time to healing, clinical outcome of burn sites (scarring) and a comparison of cost of care for patients treated with AWBAT-S versus Biobrane.

No MeSH data available.


Related in: MedlinePlus

Patient number 10 developed pigmented scars at the pore sites of Biobrane                        which persisted at 12 months.
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Figure 4: Patient number 10 developed pigmented scars at the pore sites of Biobrane which persisted at 12 months.

Mentions: A final issue relates to pore marks. This is a subject of collaborative investigation close to publication and I do not want to reveal too much about mechanism here; however, pore marks were seen in 5 of the 12 patients at the AWBAT-S treatment area compared with 4 of the 12 Biobrane site pore marks. Patient number 2 developed AWBAT-S pore marks that became prominent between 6 and 12 months and left raised pore scars at 12 months. Patient number 3, had a particularly unusual AWBAT-S pore-mark reaction, with raised prominences that persisted, leaving regular and frequent raised white scars (Figs 3a and 3b). In all but one patient (number 10), the Biobrane pore marks faded completely (2 by 3 months, 1 by 6 months); patient number 10 had pore scars from Biobrane at 12 months (Fig 4). Patient number 12 completely healed a thigh burn in AWBAT-S without any visible marks, and then developed blisters at the site of the pores after irritation while wearing nylon track pants (Fig 5). These subsequently healed without scarring. It is obvious that the pore-mark phenomenon in Biobrane is not a feature of the discontinuity of the nylon matrix at the pore site, but the discontinuity of the silicone layer. Since AWBAT-S has larger and more frequent pores, the phenomenon appears to persist for longer, and more frequently result in pore scars, than when using Biobrane. Finally, the pink colouration of the healed wound faded more quickly in AWBAT-S–treated areas than Biobrane-treated areas.


A Randomized, Prospective Study of the Treatment of Superficial Partial-Thickness Burns: AWBAT-S Versus Biobrane.

Greenwood JE - Eplasty (2011)

Patient number 10 developed pigmented scars at the pore sites of Biobrane                        which persisted at 12 months.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3045219&req=5

Figure 4: Patient number 10 developed pigmented scars at the pore sites of Biobrane which persisted at 12 months.
Mentions: A final issue relates to pore marks. This is a subject of collaborative investigation close to publication and I do not want to reveal too much about mechanism here; however, pore marks were seen in 5 of the 12 patients at the AWBAT-S treatment area compared with 4 of the 12 Biobrane site pore marks. Patient number 2 developed AWBAT-S pore marks that became prominent between 6 and 12 months and left raised pore scars at 12 months. Patient number 3, had a particularly unusual AWBAT-S pore-mark reaction, with raised prominences that persisted, leaving regular and frequent raised white scars (Figs 3a and 3b). In all but one patient (number 10), the Biobrane pore marks faded completely (2 by 3 months, 1 by 6 months); patient number 10 had pore scars from Biobrane at 12 months (Fig 4). Patient number 12 completely healed a thigh burn in AWBAT-S without any visible marks, and then developed blisters at the site of the pores after irritation while wearing nylon track pants (Fig 5). These subsequently healed without scarring. It is obvious that the pore-mark phenomenon in Biobrane is not a feature of the discontinuity of the nylon matrix at the pore site, but the discontinuity of the silicone layer. Since AWBAT-S has larger and more frequent pores, the phenomenon appears to persist for longer, and more frequently result in pore scars, than when using Biobrane. Finally, the pink colouration of the healed wound faded more quickly in AWBAT-S–treated areas than Biobrane-treated areas.

Bottom Line: The aim of this study was to prospectively evaluate AWBAT-S in comparison with Biobrane for the treatment of superficial partial-thickness burns using the patient as his or her own control.Primary outcome measures included length of hospital inpatient stay and patient-reported perception of pain.Secondary outcome measures included time to healing, clinical outcome of burn sites (scarring) and a comparison of cost of care for patients treated with AWBAT-S versus Biobrane.

View Article: PubMed Central - PubMed

Affiliation: Adult Burn Service, Royal Adelaide Hospital, North Terrace, Adelaide, South Australia, Australia.

ABSTRACT
The aim of this study was to prospectively evaluate AWBAT-S in comparison with Biobrane for the treatment of superficial partial-thickness burns using the patient as his or her own control. Primary outcome measures included length of hospital inpatient stay and patient-reported perception of pain. Secondary outcome measures included time to healing, clinical outcome of burn sites (scarring) and a comparison of cost of care for patients treated with AWBAT-S versus Biobrane.

No MeSH data available.


Related in: MedlinePlus