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Correlation of the ratio of metastatic to non-metastatic cancer cases with the degree of socioeconomic deprivation among Texas counties.

Philips BU, Gong G, Hargrave KA, Belasco E, Lyford CP - Int J Health Geogr (2011)

Bottom Line: The ten socioeconomic status variables were subjected to the principal component analysis, and the first principal component scores were grouped into deciles for the WI (1 to 10) and the 254 Texas counties were classified into 10 corresponding groups.The ratios of metastatic to non-metastatic cases of all-type, female genital system and lung cancers at diagnosis were statistically correlated with socioeconomic deprivation.Potential mediators for the correlation warrant further investigation in order to reduce health disparities associated with socioeconomic inequality.

View Article: PubMed Central - HTML - PubMed

Affiliation: F, Marie Hall Institute for Rural Community Health, Texas Tech University Health Science Center, Lubbock, Texas 79430, USA. billy.philips@ttuhsc.edu

ABSTRACT

Background: Previous studies have demonstrated that cancer registrations and hospital discharge rate are closely correlated with census data-based socioeconomic deprivation indices. We hypothesized that communities with higher degrees of socioeconomic deprivation tend to have a higher ratio of metastatic to non-metastatic cancer cases (lung, breast, prostate, female genital system, colorectal cancers or all types of cancers combined). In this study, we investigate the potential link between this ratio and the Wellbeing Index (WI) among Texas counties.

Results: Cancer data in 2000 were provided by the Texas Cancer Registry, while data on the ten socioeconomic variables among the 254 Texas counties in 2000 for building the WI were obtained from U.S. Census Bureau. The ten socioeconomic status variables were subjected to the principal component analysis, and the first principal component scores were grouped into deciles for the WI (1 to 10) and the 254 Texas counties were classified into 10 corresponding groups. Weighted linear regression analyses and a Cochran-Armitage trend test were performed to determine the relationship between the ratio of age-adjusted metastatic to non-metastatic cancer incidence cases and WI. The ratios of metastatic to non-metastatic cases of female genital system cancer (r2 = 0.84, p = 0.0002), all-type cancers (r2= 0.73, p = 0.0017) and lung cancer (r2= 0.54, p = 0.0156) at diagnosis were positively correlated with WI.

Conclusions: The ratios of metastatic to non-metastatic cases of all-type, female genital system and lung cancers at diagnosis were statistically correlated with socioeconomic deprivation. Potential mediators for the correlation warrant further investigation in order to reduce health disparities associated with socioeconomic inequality.

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Geographic distribution of counties with different WI in Texas in 2000.
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Figure 1: Geographic distribution of counties with different WI in Texas in 2000.

Mentions: Table 1 presents variables that were used to build the WI and the percentages of variance explained by each variable in its correlation with the first principal component are shown. The first principal component of the ten variables accounts for 51% of the overall variance. Figure 1 shows the geographic distribution of Texas counties with different WI based on the 2000 Census information. A large proportion of counties with WI 8-10 were distributed along the U.S.-Mexico border.


Correlation of the ratio of metastatic to non-metastatic cancer cases with the degree of socioeconomic deprivation among Texas counties.

Philips BU, Gong G, Hargrave KA, Belasco E, Lyford CP - Int J Health Geogr (2011)

Geographic distribution of counties with different WI in Texas in 2000.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3044097&req=5

Figure 1: Geographic distribution of counties with different WI in Texas in 2000.
Mentions: Table 1 presents variables that were used to build the WI and the percentages of variance explained by each variable in its correlation with the first principal component are shown. The first principal component of the ten variables accounts for 51% of the overall variance. Figure 1 shows the geographic distribution of Texas counties with different WI based on the 2000 Census information. A large proportion of counties with WI 8-10 were distributed along the U.S.-Mexico border.

Bottom Line: The ten socioeconomic status variables were subjected to the principal component analysis, and the first principal component scores were grouped into deciles for the WI (1 to 10) and the 254 Texas counties were classified into 10 corresponding groups.The ratios of metastatic to non-metastatic cases of all-type, female genital system and lung cancers at diagnosis were statistically correlated with socioeconomic deprivation.Potential mediators for the correlation warrant further investigation in order to reduce health disparities associated with socioeconomic inequality.

View Article: PubMed Central - HTML - PubMed

Affiliation: F, Marie Hall Institute for Rural Community Health, Texas Tech University Health Science Center, Lubbock, Texas 79430, USA. billy.philips@ttuhsc.edu

ABSTRACT

Background: Previous studies have demonstrated that cancer registrations and hospital discharge rate are closely correlated with census data-based socioeconomic deprivation indices. We hypothesized that communities with higher degrees of socioeconomic deprivation tend to have a higher ratio of metastatic to non-metastatic cancer cases (lung, breast, prostate, female genital system, colorectal cancers or all types of cancers combined). In this study, we investigate the potential link between this ratio and the Wellbeing Index (WI) among Texas counties.

Results: Cancer data in 2000 were provided by the Texas Cancer Registry, while data on the ten socioeconomic variables among the 254 Texas counties in 2000 for building the WI were obtained from U.S. Census Bureau. The ten socioeconomic status variables were subjected to the principal component analysis, and the first principal component scores were grouped into deciles for the WI (1 to 10) and the 254 Texas counties were classified into 10 corresponding groups. Weighted linear regression analyses and a Cochran-Armitage trend test were performed to determine the relationship between the ratio of age-adjusted metastatic to non-metastatic cancer incidence cases and WI. The ratios of metastatic to non-metastatic cases of female genital system cancer (r2 = 0.84, p = 0.0002), all-type cancers (r2= 0.73, p = 0.0017) and lung cancer (r2= 0.54, p = 0.0156) at diagnosis were positively correlated with WI.

Conclusions: The ratios of metastatic to non-metastatic cases of all-type, female genital system and lung cancers at diagnosis were statistically correlated with socioeconomic deprivation. Potential mediators for the correlation warrant further investigation in order to reduce health disparities associated with socioeconomic inequality.

Show MeSH
Related in: MedlinePlus