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Cortical modulation of the transient visual response at thalamic level: a TMS study.

Espinosa N, Mariño J, de Labra C, Cudeiro J - PLoS ONE (2011)

Bottom Line: The results show that rTMS@1Hz modulates the firing mode of Y cells, inducing an increase in burst spikes and a decrease in tonic firing.On the other hand, rTMS@1Hz modifies the spatiotemporal characteristics of receptive fields of X cells, inducing a delay and a decrease of the peak response, and a change of the surround/center amplitude ratio of RF profiles.These results indicate that V1 controls the activity of the visual thalamus in a different way in the X and Y pathways, and that this feedback control is consistent with functional roles associated with each cell type.

View Article: PubMed Central - PubMed

Affiliation: Neuroscience and Motor Control Group (NEUROcom) and Biomedical Institute of A Coruña (INIBIC), University of A Coruña, A Coruña, Spain.

ABSTRACT
The transient visual response of feline dorsal lateral geniculate nucleus (dLGN) cells was studied under control conditions and during the application of repetitive transcranial magnetic stimulation at 1 Hz (rTMS@1Hz) on the primary visual cortex (V1). The results show that rTMS@1Hz modulates the firing mode of Y cells, inducing an increase in burst spikes and a decrease in tonic firing. On the other hand, rTMS@1Hz modifies the spatiotemporal characteristics of receptive fields of X cells, inducing a delay and a decrease of the peak response, and a change of the surround/center amplitude ratio of RF profiles. These results indicate that V1 controls the activity of the visual thalamus in a different way in the X and Y pathways, and that this feedback control is consistent with functional roles associated with each cell type.

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Percentage of spikes in burst mode for X cells.A, Distribution of the percentage of spikes in burst for the response of X dLGN cells. B, In these cells, the percentage of spikes in burst remained unaltered with rTMS@1Hz.
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pone-0017041-g001: Percentage of spikes in burst mode for X cells.A, Distribution of the percentage of spikes in burst for the response of X dLGN cells. B, In these cells, the percentage of spikes in burst remained unaltered with rTMS@1Hz.

Mentions: Figure 1A shows the distribution of the percentage of spikes in burst during control condition. Statistical analysis revealed that rTMS@1Hz did not alter either the burst or tonic response, as it is shown in Figure 1B for spikes in burst.


Cortical modulation of the transient visual response at thalamic level: a TMS study.

Espinosa N, Mariño J, de Labra C, Cudeiro J - PLoS ONE (2011)

Percentage of spikes in burst mode for X cells.A, Distribution of the percentage of spikes in burst for the response of X dLGN cells. B, In these cells, the percentage of spikes in burst remained unaltered with rTMS@1Hz.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC3037393&req=5

pone-0017041-g001: Percentage of spikes in burst mode for X cells.A, Distribution of the percentage of spikes in burst for the response of X dLGN cells. B, In these cells, the percentage of spikes in burst remained unaltered with rTMS@1Hz.
Mentions: Figure 1A shows the distribution of the percentage of spikes in burst during control condition. Statistical analysis revealed that rTMS@1Hz did not alter either the burst or tonic response, as it is shown in Figure 1B for spikes in burst.

Bottom Line: The results show that rTMS@1Hz modulates the firing mode of Y cells, inducing an increase in burst spikes and a decrease in tonic firing.On the other hand, rTMS@1Hz modifies the spatiotemporal characteristics of receptive fields of X cells, inducing a delay and a decrease of the peak response, and a change of the surround/center amplitude ratio of RF profiles.These results indicate that V1 controls the activity of the visual thalamus in a different way in the X and Y pathways, and that this feedback control is consistent with functional roles associated with each cell type.

View Article: PubMed Central - PubMed

Affiliation: Neuroscience and Motor Control Group (NEUROcom) and Biomedical Institute of A Coruña (INIBIC), University of A Coruña, A Coruña, Spain.

ABSTRACT
The transient visual response of feline dorsal lateral geniculate nucleus (dLGN) cells was studied under control conditions and during the application of repetitive transcranial magnetic stimulation at 1 Hz (rTMS@1Hz) on the primary visual cortex (V1). The results show that rTMS@1Hz modulates the firing mode of Y cells, inducing an increase in burst spikes and a decrease in tonic firing. On the other hand, rTMS@1Hz modifies the spatiotemporal characteristics of receptive fields of X cells, inducing a delay and a decrease of the peak response, and a change of the surround/center amplitude ratio of RF profiles. These results indicate that V1 controls the activity of the visual thalamus in a different way in the X and Y pathways, and that this feedback control is consistent with functional roles associated with each cell type.

Show MeSH