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Emphysematous polycystic renal infection.

Sooraj YS, Nainan GK, Joseph F, Thara P - Indian J Nephrol (2010)

Bottom Line: Autosomal dominant polycystic kidney disease (ADPKD) is one of the commonest hereditary disorders.Urinary tract infection is a common complication of this disease.However emphysematous infections in ADPKD have seldom been reported.

View Article: PubMed Central - PubMed

Affiliation: Department of Nephrology, Lakeshore Hospital and Research Centre, Nettur PO, Kochi, India.

ABSTRACT
Autosomal dominant polycystic kidney disease (ADPKD) is one of the commonest hereditary disorders. Urinary tract infection is a common complication of this disease. However emphysematous infections in ADPKD have seldom been reported. We report a case of emphysematous polycystic renal infection with Gram negative (Escherichia coli) septicemia in a nondiabetic patient with ADPKD who succumbed to his illness despite aggressive management including early nephrectomy.

No MeSH data available.


Related in: MedlinePlus

CT abdomen of the patient showing bilateral enlarged kidneys with multiple cysts. One of the cysts in the right kidney shows an air bubble (see circle)
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Figure 0001: CT abdomen of the patient showing bilateral enlarged kidneys with multiple cysts. One of the cysts in the right kidney shows an air bubble (see circle)

Mentions: A 57-year-old gentleman presented with history of high-grade fever with chills and rigors. He was recently detected to have ADPKD with hypertension and ESKD, and was on conservative management. He did not suffer from diabetes mellitus. Clinical evaluation revealed the presence of bilateral nodular abdominal masses. His pulse rate was 110/min and blood pressure was 100/70 mmHg. Investigations revealed a hemoglobin level of 4.7 g/dL, total leucocyte count of 27,000/cmm with 82% neutrophils. His blood urea was 230 mg/dL and serum creatinine was 8 mg/dL. Blood and urine cultures grew Escherichia coli. Ultrasonogram of the abdomen revealed grossly enlarged kidneys with multiple cysts. CT scan of the abdomen revealed bilateral polycystic kidneys with small calculi. One of the cysts in the lower pole of the right kidney showed an air bubble [Figure 1]. A diagnosis of Emphysematous polycystic renal infection (EPRI) was made. He was treated with higher antibiotics and underwent emergency nephrectomy. He also underwent continuous renal replacement therapy. Cutsection of the resected kidney revealed the presence of numerous cysts with serous hemorrhagic material and pus. The pus culture grew E. coli. However he did not recover and succumbed to his illness.


Emphysematous polycystic renal infection.

Sooraj YS, Nainan GK, Joseph F, Thara P - Indian J Nephrol (2010)

CT abdomen of the patient showing bilateral enlarged kidneys with multiple cysts. One of the cysts in the right kidney shows an air bubble (see circle)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3008950&req=5

Figure 0001: CT abdomen of the patient showing bilateral enlarged kidneys with multiple cysts. One of the cysts in the right kidney shows an air bubble (see circle)
Mentions: A 57-year-old gentleman presented with history of high-grade fever with chills and rigors. He was recently detected to have ADPKD with hypertension and ESKD, and was on conservative management. He did not suffer from diabetes mellitus. Clinical evaluation revealed the presence of bilateral nodular abdominal masses. His pulse rate was 110/min and blood pressure was 100/70 mmHg. Investigations revealed a hemoglobin level of 4.7 g/dL, total leucocyte count of 27,000/cmm with 82% neutrophils. His blood urea was 230 mg/dL and serum creatinine was 8 mg/dL. Blood and urine cultures grew Escherichia coli. Ultrasonogram of the abdomen revealed grossly enlarged kidneys with multiple cysts. CT scan of the abdomen revealed bilateral polycystic kidneys with small calculi. One of the cysts in the lower pole of the right kidney showed an air bubble [Figure 1]. A diagnosis of Emphysematous polycystic renal infection (EPRI) was made. He was treated with higher antibiotics and underwent emergency nephrectomy. He also underwent continuous renal replacement therapy. Cutsection of the resected kidney revealed the presence of numerous cysts with serous hemorrhagic material and pus. The pus culture grew E. coli. However he did not recover and succumbed to his illness.

Bottom Line: Autosomal dominant polycystic kidney disease (ADPKD) is one of the commonest hereditary disorders.Urinary tract infection is a common complication of this disease.However emphysematous infections in ADPKD have seldom been reported.

View Article: PubMed Central - PubMed

Affiliation: Department of Nephrology, Lakeshore Hospital and Research Centre, Nettur PO, Kochi, India.

ABSTRACT
Autosomal dominant polycystic kidney disease (ADPKD) is one of the commonest hereditary disorders. Urinary tract infection is a common complication of this disease. However emphysematous infections in ADPKD have seldom been reported. We report a case of emphysematous polycystic renal infection with Gram negative (Escherichia coli) septicemia in a nondiabetic patient with ADPKD who succumbed to his illness despite aggressive management including early nephrectomy.

No MeSH data available.


Related in: MedlinePlus