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Long-term survival of living donor renal transplants: A single center study.

Hassanzadeh J, Hashiani AA, Rajaeefard A, Salahi H, Khedmati E, Kakaei F, Nikeghbalian S, Malek-Hossein A - Indian J Nephrol (2010)

Bottom Line: Mean follow-up was 53.07 ± 34.61 months.Allograft survival rates at 1, 3, 5, 7, and 10 years were 98.3, 96.4, 92.5, 90.8, and 89.2%, respectively.Using Cox proportional hazard model, the age and gender of the donors along with the creatinine level of the patients at discharge were shown to have a significant influence on survival.

View Article: PubMed Central - PubMed

Affiliation: Department of Epidemiology, School of Health and Nutrition, Shiraz University of Medical Sciences, Shiraz, Iran.

ABSTRACT
Kidney transplantation is the treatment of choice for end-stage renal disease. The aim of this study was to determine the ten-year graft survival rate of renal transplantation in patients who have been transplanted from live donors. This is a historical cohort study designed to determine the organ survival rate after kidney transplantation from live donor during a 10-year period (from March 1999 to March 2009) on 843 patients receiving kidney transplant in the transplantation center of Namazi hospital in Shiraz, Iran. Kaplan-Meier method was used to determine the survival rate, log-rank test was used to compare survival curves, and Cox proportional hazard model was used to multivariate analysis. Mean follow-up was 53.07 ± 34.61 months. Allograft survival rates at 1, 3, 5, 7, and 10 years were 98.3, 96.4, 92.5, 90.8, and 89.2%, respectively. Using Cox proportional hazard model, the age and gender of the donors along with the creatinine level of the patients at discharge were shown to have a significant influence on survival. The 10-year graft survival rate of renal transplantation from living donor in this center is 89.2%, and graft survival rate in our cohort is satisfactory and comparable with reports from large centers in the world.

No MeSH data available.


Related in: MedlinePlus

Assessment of proportionality of hazard ratio assumption using the method of predicted and observed values based on donor’s sex
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Figure 0003: Assessment of proportionality of hazard ratio assumption using the method of predicted and observed values based on donor’s sex

Mentions: Testing the AHRP using goodness of fit method showed that this assumption was true for variables. Graphic methods have been done for assessing this assumption for all variables, but because of space limitations of this article, these methods have been shown only for variables of donor’s age [Figure 2] and donor’s sex [Figure 3] as examples.


Long-term survival of living donor renal transplants: A single center study.

Hassanzadeh J, Hashiani AA, Rajaeefard A, Salahi H, Khedmati E, Kakaei F, Nikeghbalian S, Malek-Hossein A - Indian J Nephrol (2010)

Assessment of proportionality of hazard ratio assumption using the method of predicted and observed values based on donor’s sex
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC3008945&req=5

Figure 0003: Assessment of proportionality of hazard ratio assumption using the method of predicted and observed values based on donor’s sex
Mentions: Testing the AHRP using goodness of fit method showed that this assumption was true for variables. Graphic methods have been done for assessing this assumption for all variables, but because of space limitations of this article, these methods have been shown only for variables of donor’s age [Figure 2] and donor’s sex [Figure 3] as examples.

Bottom Line: Mean follow-up was 53.07 ± 34.61 months.Allograft survival rates at 1, 3, 5, 7, and 10 years were 98.3, 96.4, 92.5, 90.8, and 89.2%, respectively.Using Cox proportional hazard model, the age and gender of the donors along with the creatinine level of the patients at discharge were shown to have a significant influence on survival.

View Article: PubMed Central - PubMed

Affiliation: Department of Epidemiology, School of Health and Nutrition, Shiraz University of Medical Sciences, Shiraz, Iran.

ABSTRACT
Kidney transplantation is the treatment of choice for end-stage renal disease. The aim of this study was to determine the ten-year graft survival rate of renal transplantation in patients who have been transplanted from live donors. This is a historical cohort study designed to determine the organ survival rate after kidney transplantation from live donor during a 10-year period (from March 1999 to March 2009) on 843 patients receiving kidney transplant in the transplantation center of Namazi hospital in Shiraz, Iran. Kaplan-Meier method was used to determine the survival rate, log-rank test was used to compare survival curves, and Cox proportional hazard model was used to multivariate analysis. Mean follow-up was 53.07 ± 34.61 months. Allograft survival rates at 1, 3, 5, 7, and 10 years were 98.3, 96.4, 92.5, 90.8, and 89.2%, respectively. Using Cox proportional hazard model, the age and gender of the donors along with the creatinine level of the patients at discharge were shown to have a significant influence on survival. The 10-year graft survival rate of renal transplantation from living donor in this center is 89.2%, and graft survival rate in our cohort is satisfactory and comparable with reports from large centers in the world.

No MeSH data available.


Related in: MedlinePlus