Limits...
Progression rate of total, and upper and lower visual field defects in open-angle glaucoma patients.

Fukuchi T, Yoshino T, Sawada H, Seki M, Togano T, Tanaka T, Ueda J, Abe H - Clin Ophthalmol (2010)

Bottom Line: The mean deviation (MD) and total deviation (TD) for both the upper and lower slopes on the Humphrey Field Analyzer were calculated and compared in high-tension glaucoma (>21 mmHg) and normal-tension glaucoma (≤21 mmHg).Comparing high-tension glaucoma and normal-tension glaucoma, the upper TD slope was similar for both types of glaucoma, but the MD and lower TD slopes in high-tension glaucoma were significantly lower than those in normal-tension glaucoma.The progression rates in lower visual field defects in high-tension glaucoma might be faster than those in normal-tension glaucoma.

View Article: PubMed Central - PubMed

Affiliation: Division of Ophthalmology and Visual Science, Graduated School of Medical and Dental Sciences, Niigata University, Niigata, Japan.

ABSTRACT

Purpose: We evaluated the progression rate of total, and upper and lower visual field defects in treated open-angle glaucoma patients.

Patients and methods: This study was a retrospective, nonrandomized, comparative study. Five-hundred forty-four eyes from 315 Japanese open-angle glaucoma patients were examined. The mean deviation (MD) and total deviation (TD) for both the upper and lower slopes on the Humphrey Field Analyzer were calculated and compared in high-tension glaucoma (>21 mmHg) and normal-tension glaucoma (≤21 mmHg).

Results: Patients with over -20 dB of MD and over -23 dB of upper or lower TD were enrolled into each analysis. Patients with -7.75 ± 5.30 (mean ± standard deviation) dB of MD, -9.16 ± 10.80 dB of upper TD, or -7.11 ± 6.02 dB of lower TD were followed up for 4-19 years. The mean MD slope was -0.41 ± 0.50 dB/year, the upper TD slope was -0.46 ± 0.65 dB/year, and the lower TD slope was -0.32 ± 0.53 dB/year. Comparing high-tension glaucoma and normal-tension glaucoma, the upper TD slope was similar for both types of glaucoma, but the MD and lower TD slopes in high-tension glaucoma were significantly lower than those in normal-tension glaucoma.

Conclusions: The progression rates in lower visual field defects in high-tension glaucoma might be faster than those in normal-tension glaucoma. The results of this study might be used to predict the prognosis of visual field defects, as well as the quality of vision in patients with open-angle glaucoma.

No MeSH data available.


Related in: MedlinePlus

Frequency distributions of mean deviation (MD) slope A), upper total deviation (upper TD) slope B) and lower total deviation (lower TD) slope C) in the patients with HTG (black bar) and NTG (gray bar).
© Copyright Policy
Related In: Results  -  Collection


getmorefigures.php?uid=PMC2993106&req=5

f1-opth-4-1315: Frequency distributions of mean deviation (MD) slope A), upper total deviation (upper TD) slope B) and lower total deviation (lower TD) slope C) in the patients with HTG (black bar) and NTG (gray bar).

Mentions: The frequency distribution of the MD slope for hightension glaucoma and normal-tension glaucoma is shown in Figure 1A. In both the high-tension glaucoma and normaltension glaucoma groups, eyes with an MD slope between 0 and −0.5 dB/year were seen most frequently. The frequency of an MD slope between 0 and −0.5 dB/year was greater in normal-tension glaucoma than in high-tension glaucoma. In the cases studied for MD slope evaluation, the mean follow-up term; initial age; initial MD; MD slope; and number of eyes with statistical progression, rapid progression, or moderate progression in open-angle glaucoma, high-tension glaucoma, and normal-tension glaucoma are shown in Table 2. There was no statistically significant difference in mean follow-up duration and initial MD between high-tension and normal-tension glaucoma. The prevalence of statistical progression was similar between the two groups. However, the mean MD slope was lower and there were more eyes with moderate or rapid progression in the high-tension glaucoma group than in the normal-tension glaucoma group.


Progression rate of total, and upper and lower visual field defects in open-angle glaucoma patients.

Fukuchi T, Yoshino T, Sawada H, Seki M, Togano T, Tanaka T, Ueda J, Abe H - Clin Ophthalmol (2010)

Frequency distributions of mean deviation (MD) slope A), upper total deviation (upper TD) slope B) and lower total deviation (lower TD) slope C) in the patients with HTG (black bar) and NTG (gray bar).
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2993106&req=5

f1-opth-4-1315: Frequency distributions of mean deviation (MD) slope A), upper total deviation (upper TD) slope B) and lower total deviation (lower TD) slope C) in the patients with HTG (black bar) and NTG (gray bar).
Mentions: The frequency distribution of the MD slope for hightension glaucoma and normal-tension glaucoma is shown in Figure 1A. In both the high-tension glaucoma and normaltension glaucoma groups, eyes with an MD slope between 0 and −0.5 dB/year were seen most frequently. The frequency of an MD slope between 0 and −0.5 dB/year was greater in normal-tension glaucoma than in high-tension glaucoma. In the cases studied for MD slope evaluation, the mean follow-up term; initial age; initial MD; MD slope; and number of eyes with statistical progression, rapid progression, or moderate progression in open-angle glaucoma, high-tension glaucoma, and normal-tension glaucoma are shown in Table 2. There was no statistically significant difference in mean follow-up duration and initial MD between high-tension and normal-tension glaucoma. The prevalence of statistical progression was similar between the two groups. However, the mean MD slope was lower and there were more eyes with moderate or rapid progression in the high-tension glaucoma group than in the normal-tension glaucoma group.

Bottom Line: The mean deviation (MD) and total deviation (TD) for both the upper and lower slopes on the Humphrey Field Analyzer were calculated and compared in high-tension glaucoma (>21 mmHg) and normal-tension glaucoma (≤21 mmHg).Comparing high-tension glaucoma and normal-tension glaucoma, the upper TD slope was similar for both types of glaucoma, but the MD and lower TD slopes in high-tension glaucoma were significantly lower than those in normal-tension glaucoma.The progression rates in lower visual field defects in high-tension glaucoma might be faster than those in normal-tension glaucoma.

View Article: PubMed Central - PubMed

Affiliation: Division of Ophthalmology and Visual Science, Graduated School of Medical and Dental Sciences, Niigata University, Niigata, Japan.

ABSTRACT

Purpose: We evaluated the progression rate of total, and upper and lower visual field defects in treated open-angle glaucoma patients.

Patients and methods: This study was a retrospective, nonrandomized, comparative study. Five-hundred forty-four eyes from 315 Japanese open-angle glaucoma patients were examined. The mean deviation (MD) and total deviation (TD) for both the upper and lower slopes on the Humphrey Field Analyzer were calculated and compared in high-tension glaucoma (>21 mmHg) and normal-tension glaucoma (≤21 mmHg).

Results: Patients with over -20 dB of MD and over -23 dB of upper or lower TD were enrolled into each analysis. Patients with -7.75 ± 5.30 (mean ± standard deviation) dB of MD, -9.16 ± 10.80 dB of upper TD, or -7.11 ± 6.02 dB of lower TD were followed up for 4-19 years. The mean MD slope was -0.41 ± 0.50 dB/year, the upper TD slope was -0.46 ± 0.65 dB/year, and the lower TD slope was -0.32 ± 0.53 dB/year. Comparing high-tension glaucoma and normal-tension glaucoma, the upper TD slope was similar for both types of glaucoma, but the MD and lower TD slopes in high-tension glaucoma were significantly lower than those in normal-tension glaucoma.

Conclusions: The progression rates in lower visual field defects in high-tension glaucoma might be faster than those in normal-tension glaucoma. The results of this study might be used to predict the prognosis of visual field defects, as well as the quality of vision in patients with open-angle glaucoma.

No MeSH data available.


Related in: MedlinePlus