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Orbital metastatic angiosarcoma.

Hassane S, Fouad E, Said I, Karim R, Asmae N, Houcine C, Abdelbar O - Korean J Ophthalmol (2010)

Bottom Line: A 48-year-old man was first sent to us for a check up of proptosis of the left eye.A left orbital tumor was recognized on orbital computed tomography scans.In summary, we believed that the orbital tumour was an initial symptom of the metastasis ensuing from the lung angiosarcoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Mohammed V Military Teaching Hospital, University of King Mohammed V-Souissi, Rabat, Morocco.

ABSTRACT
We report a case of a 48-year-old man who developed metastatic angiosarcoma in her left orbit. A 48-year-old man was first sent to us for a check up of proptosis of the left eye. A left orbital tumor was recognized on orbital computed tomography scans. The open biopsy showed angiosarcoma. Chest X-ray films and thoracic computed tomography showed an abnormal mass in the left inferior lung field. Angiosarcoma was confirmed by transbronchial lung biopsy. In summary, we believed that the orbital tumour was an initial symptom of the metastasis ensuing from the lung angiosarcoma.

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Tumoral cells are staining by factor VIII.
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Figure 5: Tumoral cells are staining by factor VIII.

Mentions: Computed tomography (CT) showed a left superior orbital mass causing bone destruction, was extended to brain (Fig. 2), the radiologist suspected a metastasis with unknown primary site. Therefore, a more thorough systemic evaluation was started to detect primary malignancy. The immunohistologic staining of the incisional biopsy specimen showed angiosarcoma, the tumor cells were positive for factor VIII and CD31 (Figs. 3-5). The biopsy was complicated by inflammatory edema of the orbit (Fig. 6). A chest X-ray film completed by thoracic CT has shown an abnormal mass in the left posterior and inferior lung field (Fig. 7). Angiosarcoma has been diagnosed by transbronchial lung biopsy in immunohistological study (Fig. 8). The left orbital tumor was thought to be a metastasis caused by the lung cancer.


Orbital metastatic angiosarcoma.

Hassane S, Fouad E, Said I, Karim R, Asmae N, Houcine C, Abdelbar O - Korean J Ophthalmol (2010)

Tumoral cells are staining by factor VIII.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2992565&req=5

Figure 5: Tumoral cells are staining by factor VIII.
Mentions: Computed tomography (CT) showed a left superior orbital mass causing bone destruction, was extended to brain (Fig. 2), the radiologist suspected a metastasis with unknown primary site. Therefore, a more thorough systemic evaluation was started to detect primary malignancy. The immunohistologic staining of the incisional biopsy specimen showed angiosarcoma, the tumor cells were positive for factor VIII and CD31 (Figs. 3-5). The biopsy was complicated by inflammatory edema of the orbit (Fig. 6). A chest X-ray film completed by thoracic CT has shown an abnormal mass in the left posterior and inferior lung field (Fig. 7). Angiosarcoma has been diagnosed by transbronchial lung biopsy in immunohistological study (Fig. 8). The left orbital tumor was thought to be a metastasis caused by the lung cancer.

Bottom Line: A 48-year-old man was first sent to us for a check up of proptosis of the left eye.A left orbital tumor was recognized on orbital computed tomography scans.In summary, we believed that the orbital tumour was an initial symptom of the metastasis ensuing from the lung angiosarcoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Mohammed V Military Teaching Hospital, University of King Mohammed V-Souissi, Rabat, Morocco.

ABSTRACT
We report a case of a 48-year-old man who developed metastatic angiosarcoma in her left orbit. A 48-year-old man was first sent to us for a check up of proptosis of the left eye. A left orbital tumor was recognized on orbital computed tomography scans. The open biopsy showed angiosarcoma. Chest X-ray films and thoracic computed tomography showed an abnormal mass in the left inferior lung field. Angiosarcoma was confirmed by transbronchial lung biopsy. In summary, we believed that the orbital tumour was an initial symptom of the metastasis ensuing from the lung angiosarcoma.

Show MeSH
Related in: MedlinePlus