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Characterization of peripapillary atrophy using spectral domain optical coherence tomography.

Na JH, Moon BG, Sung KR, Lee Y, Kook MS - Korean J Ophthalmol (2010)

Bottom Line: The BRL was incomplete or showed posterior bowing in the β-zone of five eyes.The common findings in the PPA β-zone were that the RNFL was present, but the photoreceptor layer was absent.Presence of the BRL was variable in the β-zone areas.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

ABSTRACT

Purpose: To characterize the features of peripapillary atrophy (PPA), as imaged by spectral-domain optical coherence tomography (SD-OCT).

Methods: SD-OCT imaging of the optic disc was performed on healthy eyes, eyes suspected of having glaucoma, and eyes diagnosed with glaucoma. From the peripheral β-zone, the retinal nerve fiber layer (RNFL), the junction of the inner and outer segments (IS/OS) of the photoreceptor layer, and the Bruch's membrane/retinal pigment epithelium complex layer (BRL) were visualized.

Results: Nineteen consecutive eyes of 10 subjects were imaged. The RNFL was observed in the PPA β-zone of all eyes, and no eye showed an IS/OS complex in the β-zone. The BRL was absent in the β-zone of two eyes. The BRL was incomplete or showed posterior bowing in the β-zone of five eyes.

Conclusions: The common findings in the PPA β-zone were that the RNFL was present, but the photoreceptor layer was absent. Presence of the BRL was variable in the β-zone areas.

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Related in: MedlinePlus

(A) The optic disc image acquired in the fast optic disc mode of the Stratus optical coherence tomography (OCT). The posterior boundary of the retina was shown as a single thick hyper-reflective red-colored band, displayed in false color (black arrow). This posterior boundary has been interpreted as the complex of the retinal pigment epithelium (RPE) and the junction between the inner and outer segment (IS/OS) of photoreceptor layer. The white arrow indicates peripapillary retinal nerve fiber layer (RNFL). (B) Spectralis OCT images showed posterior retinal boundaries as composed of at least two layers, one thick and one thin layer. The red arrow indicates peripapillary RNFL, and the inner thinner layer has been defined as the junction between the IS/OS of the photoreceptor layer (yellow arrow), whereas the outer thicker layer has been considered to represent the Bruch's membrane/RPE border (blue arrow).
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Figure 1: (A) The optic disc image acquired in the fast optic disc mode of the Stratus optical coherence tomography (OCT). The posterior boundary of the retina was shown as a single thick hyper-reflective red-colored band, displayed in false color (black arrow). This posterior boundary has been interpreted as the complex of the retinal pigment epithelium (RPE) and the junction between the inner and outer segment (IS/OS) of photoreceptor layer. The white arrow indicates peripapillary retinal nerve fiber layer (RNFL). (B) Spectralis OCT images showed posterior retinal boundaries as composed of at least two layers, one thick and one thin layer. The red arrow indicates peripapillary RNFL, and the inner thinner layer has been defined as the junction between the IS/OS of the photoreceptor layer (yellow arrow), whereas the outer thicker layer has been considered to represent the Bruch's membrane/RPE border (blue arrow).

Mentions: Optic disc scan images acquired by the Spectralis OCT show the detailed configuration of the retinal layer posterior boundary. With the Stratus OCT, the optic disc image acquired in the fast mode, featuring 128 A scans, shows the posterior boundary as a single thick hyper-reflective red-colored band, displayed in false color (Fig. 1A, black arrow). This posterior boundary has been interpreted as the complex of the RPE and the junction between the inner and outer segment (IS/OS) of the photoreceptor layer. In Fig. 1A, a white arrow indicates peripapillary RNFL.


Characterization of peripapillary atrophy using spectral domain optical coherence tomography.

Na JH, Moon BG, Sung KR, Lee Y, Kook MS - Korean J Ophthalmol (2010)

(A) The optic disc image acquired in the fast optic disc mode of the Stratus optical coherence tomography (OCT). The posterior boundary of the retina was shown as a single thick hyper-reflective red-colored band, displayed in false color (black arrow). This posterior boundary has been interpreted as the complex of the retinal pigment epithelium (RPE) and the junction between the inner and outer segment (IS/OS) of photoreceptor layer. The white arrow indicates peripapillary retinal nerve fiber layer (RNFL). (B) Spectralis OCT images showed posterior retinal boundaries as composed of at least two layers, one thick and one thin layer. The red arrow indicates peripapillary RNFL, and the inner thinner layer has been defined as the junction between the IS/OS of the photoreceptor layer (yellow arrow), whereas the outer thicker layer has been considered to represent the Bruch's membrane/RPE border (blue arrow).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2992563&req=5

Figure 1: (A) The optic disc image acquired in the fast optic disc mode of the Stratus optical coherence tomography (OCT). The posterior boundary of the retina was shown as a single thick hyper-reflective red-colored band, displayed in false color (black arrow). This posterior boundary has been interpreted as the complex of the retinal pigment epithelium (RPE) and the junction between the inner and outer segment (IS/OS) of photoreceptor layer. The white arrow indicates peripapillary retinal nerve fiber layer (RNFL). (B) Spectralis OCT images showed posterior retinal boundaries as composed of at least two layers, one thick and one thin layer. The red arrow indicates peripapillary RNFL, and the inner thinner layer has been defined as the junction between the IS/OS of the photoreceptor layer (yellow arrow), whereas the outer thicker layer has been considered to represent the Bruch's membrane/RPE border (blue arrow).
Mentions: Optic disc scan images acquired by the Spectralis OCT show the detailed configuration of the retinal layer posterior boundary. With the Stratus OCT, the optic disc image acquired in the fast mode, featuring 128 A scans, shows the posterior boundary as a single thick hyper-reflective red-colored band, displayed in false color (Fig. 1A, black arrow). This posterior boundary has been interpreted as the complex of the RPE and the junction between the inner and outer segment (IS/OS) of the photoreceptor layer. In Fig. 1A, a white arrow indicates peripapillary RNFL.

Bottom Line: The BRL was incomplete or showed posterior bowing in the β-zone of five eyes.The common findings in the PPA β-zone were that the RNFL was present, but the photoreceptor layer was absent.Presence of the BRL was variable in the β-zone areas.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

ABSTRACT

Purpose: To characterize the features of peripapillary atrophy (PPA), as imaged by spectral-domain optical coherence tomography (SD-OCT).

Methods: SD-OCT imaging of the optic disc was performed on healthy eyes, eyes suspected of having glaucoma, and eyes diagnosed with glaucoma. From the peripheral β-zone, the retinal nerve fiber layer (RNFL), the junction of the inner and outer segments (IS/OS) of the photoreceptor layer, and the Bruch's membrane/retinal pigment epithelium complex layer (BRL) were visualized.

Results: Nineteen consecutive eyes of 10 subjects were imaged. The RNFL was observed in the PPA β-zone of all eyes, and no eye showed an IS/OS complex in the β-zone. The BRL was absent in the β-zone of two eyes. The BRL was incomplete or showed posterior bowing in the β-zone of five eyes.

Conclusions: The common findings in the PPA β-zone were that the RNFL was present, but the photoreceptor layer was absent. Presence of the BRL was variable in the β-zone areas.

Show MeSH
Related in: MedlinePlus