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Lack of awareness of erectile dysfunction in many men with risk factors for erectile dysfunction.

Shabsigh R, Kaufman J, Magee M, Creanga D, Russell D, Budhwani M - BMC Urol (2010)

Bottom Line: Of 1084 men screened, 1053 answered the screening question and also had IIEF-EF scores.Of 139 answering "yes," 526 answering "unsure," and 388 answering "no," 96%, 90%, and 36%, respectively, had some degree of erectile dysfunction.The mean±SD (range) number of risk factors was 2.9 ± 1.7 (3-8) in the "yes" group, 3.2 ± 1.7 (3-9) in the "unsure" group, and 2.6 ± 1.5 (2-8) in the "no" group.

View Article: PubMed Central - HTML - PubMed

Affiliation: Maimonides Medical Center, Brooklyn, NY, and Columbia University, New York, NY, USA.

ABSTRACT

Background: Men with erectile dysfunction often have concurrent medical conditions. Conversely, men with these conditions may also have underlying erectile dysfunction. The prevalence of unrecognized erectile dysfunction in men with comorbidities commonly associated with erectile dysfunction was determined in men invited to participate in a double-blind, randomized, placebo-controlled trial of sildenafil citrate.

Methods: Men ≥30 years old presenting with ≥1 erectile dysfunction risk factor (controlled hypertension, hypercholesterolemia, smoking, metabolic syndrome, stable coronary artery disease, diabetes, depression, lower urinary tract symptoms, obesity [body mass index ≥30 kg/m2] or waist circumference ≥40 inches), and not previously diagnosed with erectile dysfunction were evaluated. The screening question, "Do you have erectile dysfunction?," with responses of "no," "yes," and "unsure," and the Erectile Function domain of the International Index of Erectile Function (IIEF-EF) were administered.

Results: Of 1084 men screened, 1053 answered the screening question and also had IIEF-EF scores. IIEF-EF scores indicating erectile dysfunction occurred in 71% (744/1053), of whom 54% (399/744) had moderate or severe erectile dysfunction. Of 139 answering "yes," 526 answering "unsure," and 388 answering "no," 96%, 90%, and 36%, respectively, had some degree of erectile dysfunction. The mean±SD (range) number of risk factors was 2.9 ± 1.7 (3-8) in the "yes" group, 3.2 ± 1.7 (3-9) in the "unsure" group, and 2.6 ± 1.5 (2-8) in the "no" group.

Conclusion: Although awareness of having erectile dysfunction was low, most men with risk factors had IIEF-EF scores indicating erectile dysfunction. Erectile dysfunction should be suspected and assessed in men with risk factors, regardless of their apparent level of awareness of erectile dysfunction.

Trial registration: ClinicalTrials.gov Identifier NCT00343200.

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Related in: MedlinePlus

Comparison of erectile dysfunction severity in comorbidity subgroups by screening question response. LUTS = lower urinary tract symptoms. Erectile Function domain of the International Index of Erectile Function severity categories are no ED (score ≥26 out of 30), mild (score 22-25), mild-to-moderate (score 17-21), moderate (score 11-16), and severe (score ≤10)[13,14].
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Figure 3: Comparison of erectile dysfunction severity in comorbidity subgroups by screening question response. LUTS = lower urinary tract symptoms. Erectile Function domain of the International Index of Erectile Function severity categories are no ED (score ≥26 out of 30), mild (score 22-25), mild-to-moderate (score 17-21), moderate (score 11-16), and severe (score ≤10)[13,14].

Mentions: The erectile dysfunction severity profiles for each response group for the individual comorbidities generally reflected the pattern observed in the overall population; most men who answered "no" to the screening question had no erectile dysfunction or mild erectile dysfunction, those who answered "yes" had mostly moderate and severe erectile dysfunction, and those who answered "unsure" had erectile dysfunction severity that was almost equally distributed across the erectile dysfunction severity categories (Figure 3). However, in the subgroups of men with coronary artery disease and those with diabetes, a higher proportion of men in the "unsure" groups had severe erectile dysfunction compared with the other comorbidities.


Lack of awareness of erectile dysfunction in many men with risk factors for erectile dysfunction.

Shabsigh R, Kaufman J, Magee M, Creanga D, Russell D, Budhwani M - BMC Urol (2010)

Comparison of erectile dysfunction severity in comorbidity subgroups by screening question response. LUTS = lower urinary tract symptoms. Erectile Function domain of the International Index of Erectile Function severity categories are no ED (score ≥26 out of 30), mild (score 22-25), mild-to-moderate (score 17-21), moderate (score 11-16), and severe (score ≤10)[13,14].
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2991280&req=5

Figure 3: Comparison of erectile dysfunction severity in comorbidity subgroups by screening question response. LUTS = lower urinary tract symptoms. Erectile Function domain of the International Index of Erectile Function severity categories are no ED (score ≥26 out of 30), mild (score 22-25), mild-to-moderate (score 17-21), moderate (score 11-16), and severe (score ≤10)[13,14].
Mentions: The erectile dysfunction severity profiles for each response group for the individual comorbidities generally reflected the pattern observed in the overall population; most men who answered "no" to the screening question had no erectile dysfunction or mild erectile dysfunction, those who answered "yes" had mostly moderate and severe erectile dysfunction, and those who answered "unsure" had erectile dysfunction severity that was almost equally distributed across the erectile dysfunction severity categories (Figure 3). However, in the subgroups of men with coronary artery disease and those with diabetes, a higher proportion of men in the "unsure" groups had severe erectile dysfunction compared with the other comorbidities.

Bottom Line: Of 1084 men screened, 1053 answered the screening question and also had IIEF-EF scores.Of 139 answering "yes," 526 answering "unsure," and 388 answering "no," 96%, 90%, and 36%, respectively, had some degree of erectile dysfunction.The mean±SD (range) number of risk factors was 2.9 ± 1.7 (3-8) in the "yes" group, 3.2 ± 1.7 (3-9) in the "unsure" group, and 2.6 ± 1.5 (2-8) in the "no" group.

View Article: PubMed Central - HTML - PubMed

Affiliation: Maimonides Medical Center, Brooklyn, NY, and Columbia University, New York, NY, USA.

ABSTRACT

Background: Men with erectile dysfunction often have concurrent medical conditions. Conversely, men with these conditions may also have underlying erectile dysfunction. The prevalence of unrecognized erectile dysfunction in men with comorbidities commonly associated with erectile dysfunction was determined in men invited to participate in a double-blind, randomized, placebo-controlled trial of sildenafil citrate.

Methods: Men ≥30 years old presenting with ≥1 erectile dysfunction risk factor (controlled hypertension, hypercholesterolemia, smoking, metabolic syndrome, stable coronary artery disease, diabetes, depression, lower urinary tract symptoms, obesity [body mass index ≥30 kg/m2] or waist circumference ≥40 inches), and not previously diagnosed with erectile dysfunction were evaluated. The screening question, "Do you have erectile dysfunction?," with responses of "no," "yes," and "unsure," and the Erectile Function domain of the International Index of Erectile Function (IIEF-EF) were administered.

Results: Of 1084 men screened, 1053 answered the screening question and also had IIEF-EF scores. IIEF-EF scores indicating erectile dysfunction occurred in 71% (744/1053), of whom 54% (399/744) had moderate or severe erectile dysfunction. Of 139 answering "yes," 526 answering "unsure," and 388 answering "no," 96%, 90%, and 36%, respectively, had some degree of erectile dysfunction. The mean±SD (range) number of risk factors was 2.9 ± 1.7 (3-8) in the "yes" group, 3.2 ± 1.7 (3-9) in the "unsure" group, and 2.6 ± 1.5 (2-8) in the "no" group.

Conclusion: Although awareness of having erectile dysfunction was low, most men with risk factors had IIEF-EF scores indicating erectile dysfunction. Erectile dysfunction should be suspected and assessed in men with risk factors, regardless of their apparent level of awareness of erectile dysfunction.

Trial registration: ClinicalTrials.gov Identifier NCT00343200.

Show MeSH
Related in: MedlinePlus