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Central aortic valve coaptation area during diastole as seen by 64-multidetector computed tomography (MDCT).

Zeb I, Mao SS, Hamirani YS, Raina S, Kadakia J, Elamir S, Budoff MJ - Int J Cardiovasc Imaging (2010)

Bottom Line: The aortic valve coaptation area (mm(2)) measurement in patients without AR was: 4.90 ± 0.17 and in patients with AR: 10.53 ± 0.26 (P ≤ 0.05).On Bland-Altman analysis a very good correlation between central aortic valve coaptation area and central ROA was found (r = 0.80, P ≤ 0.001).Central aortic valve coaptation area is a central area present at the coaptation of nodules of arantius of aortic cusps during diastole; it is incompetent and increased in size in patients with aortic regurgitation.

View Article: PubMed Central - PubMed

Affiliation: Los Angeles Biomedical Research Institute at Harbor-UCLA, Torrance, CA 90502, USA.

ABSTRACT
As multiple new procedures now require better visualization of the aortic valve, we sought to better define the central aortic valve coaptation area seen during diastole on multi-detector row cardiac computed tomography (MDCT). 64-MDCT images of 384 symptomatic consecutive patients referred for coronary artery disease evaluation were included in the study. Planimetric measurements of this area were performed on cross-sectional views of the aortic valve at 75% phase of the cardiac cycle. Planimetric measurement of central regurgitation orifice area (ROA) seen in patients with aortic regurgitation and Hounsfield units of the central aortic valve coaptation area were performed. Mean area of the central aortic valve coaptation area was 5.34 ± 5.19 mm(2) and Hounsfield units in this area were 123.69 ± 31.31 HU. The aortic valve coaptation area (mm(2)) measurement in patients without AR was: 4.90 ± 0.17 and in patients with AR: 10.53 ± 0.26 (P ≤ 0.05). On Bland-Altman analysis a very good correlation between central aortic valve coaptation area and central ROA was found (r = 0.80, P ≤ 0.001). Central aortic valve coaptation area is a central area present at the coaptation of nodules of arantius of aortic cusps during diastole; it is incompetent and increased in size in patients with aortic regurgitation.

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Bland Altman correlation between central aortic valve coaptation area and aortic regurgitation orifice area
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Fig3: Bland Altman correlation between central aortic valve coaptation area and aortic regurgitation orifice area

Mentions: General characteristics of the patient population are given in the Table 1. Mean area of the central aortic valve coaptation area on planimetric measurement was 5.34 ± 5.19 mm2. Mean Hounsfield units in this area were 123.69 ± 31.31 HU. Incomplete co-aptation of the aortic valve cusps as ROA was noticed on 29 patients. We followed trans-thoracic echocardiography (TTE) reports on these 29 patients and all of them were found to have aortic regurgitation of various severities on TTE. Mean central aortic valve coaptation area (mm2) in patients with aortic regurgitation was 10.53 ± 0.26 and in patients without aortic regurgitation were 4.90 ± 0.17. There was correlation found between central aortic valve coaptation area and central ROA using Bland–Altman correlation which showed that with increase in ROA area, the central aortic valve coaptation area also increases in size (r = 0.80, P = <0.001) (Fig. 3). The average aortic valve calcium score in the whole cohort was 8.49 ± 64.45 AU.Table 1


Central aortic valve coaptation area during diastole as seen by 64-multidetector computed tomography (MDCT).

Zeb I, Mao SS, Hamirani YS, Raina S, Kadakia J, Elamir S, Budoff MJ - Int J Cardiovasc Imaging (2010)

Bland Altman correlation between central aortic valve coaptation area and aortic regurgitation orifice area
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2991237&req=5

Fig3: Bland Altman correlation between central aortic valve coaptation area and aortic regurgitation orifice area
Mentions: General characteristics of the patient population are given in the Table 1. Mean area of the central aortic valve coaptation area on planimetric measurement was 5.34 ± 5.19 mm2. Mean Hounsfield units in this area were 123.69 ± 31.31 HU. Incomplete co-aptation of the aortic valve cusps as ROA was noticed on 29 patients. We followed trans-thoracic echocardiography (TTE) reports on these 29 patients and all of them were found to have aortic regurgitation of various severities on TTE. Mean central aortic valve coaptation area (mm2) in patients with aortic regurgitation was 10.53 ± 0.26 and in patients without aortic regurgitation were 4.90 ± 0.17. There was correlation found between central aortic valve coaptation area and central ROA using Bland–Altman correlation which showed that with increase in ROA area, the central aortic valve coaptation area also increases in size (r = 0.80, P = <0.001) (Fig. 3). The average aortic valve calcium score in the whole cohort was 8.49 ± 64.45 AU.Table 1

Bottom Line: The aortic valve coaptation area (mm(2)) measurement in patients without AR was: 4.90 ± 0.17 and in patients with AR: 10.53 ± 0.26 (P ≤ 0.05).On Bland-Altman analysis a very good correlation between central aortic valve coaptation area and central ROA was found (r = 0.80, P ≤ 0.001).Central aortic valve coaptation area is a central area present at the coaptation of nodules of arantius of aortic cusps during diastole; it is incompetent and increased in size in patients with aortic regurgitation.

View Article: PubMed Central - PubMed

Affiliation: Los Angeles Biomedical Research Institute at Harbor-UCLA, Torrance, CA 90502, USA.

ABSTRACT
As multiple new procedures now require better visualization of the aortic valve, we sought to better define the central aortic valve coaptation area seen during diastole on multi-detector row cardiac computed tomography (MDCT). 64-MDCT images of 384 symptomatic consecutive patients referred for coronary artery disease evaluation were included in the study. Planimetric measurements of this area were performed on cross-sectional views of the aortic valve at 75% phase of the cardiac cycle. Planimetric measurement of central regurgitation orifice area (ROA) seen in patients with aortic regurgitation and Hounsfield units of the central aortic valve coaptation area were performed. Mean area of the central aortic valve coaptation area was 5.34 ± 5.19 mm(2) and Hounsfield units in this area were 123.69 ± 31.31 HU. The aortic valve coaptation area (mm(2)) measurement in patients without AR was: 4.90 ± 0.17 and in patients with AR: 10.53 ± 0.26 (P ≤ 0.05). On Bland-Altman analysis a very good correlation between central aortic valve coaptation area and central ROA was found (r = 0.80, P ≤ 0.001). Central aortic valve coaptation area is a central area present at the coaptation of nodules of arantius of aortic cusps during diastole; it is incompetent and increased in size in patients with aortic regurgitation.

Show MeSH
Related in: MedlinePlus