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Primary pulmonary plasmacytoma with diffuse alveolar consolidation: a case report.

Mohammad Taheri Z, Mohammadi F, Karbasi M, Seyfollahi L, Kahkoei S, Ghadiany M, Fayazi N, Mansouri D - Patholog Res Int (2010)

Bottom Line: Solitary extramedullary plasmacytomas are plasma cell tumors that tend to develop in mucosa-associated lymphoid tissues including the sinonasal or nasopharyngeal regions.Primary plasmacytoma of the lung is exceedingly rare and often presents as a solitary mass or nodule in mid-lung or hilar areas and diagnosed after resection.Herein, we report a case of primary pulmonary plasmacytoma that presented with diffuse alveolar consolidation and diagnosed by transbronchial lung biopsy.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, National Research Institute of Tuberculosis and Lung Disease, Tehran 19569, Iran.

ABSTRACT
Solitary extramedullary plasmacytomas are plasma cell tumors that tend to develop in mucosa-associated lymphoid tissues including the sinonasal or nasopharyngeal regions. Primary plasmacytoma of the lung is exceedingly rare and often presents as a solitary mass or nodule in mid-lung or hilar areas and diagnosed after resection. Herein, we report a case of primary pulmonary plasmacytoma that presented with diffuse alveolar consolidation and diagnosed by transbronchial lung biopsy.

No MeSH data available.


Related in: MedlinePlus

The proliferated cells showing strong positivity for CD138 in Immunohistochemistry staining.
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fig4: The proliferated cells showing strong positivity for CD138 in Immunohistochemistry staining.

Mentions: Transbronchial lung biopsy was done and pathologic examination of the specimen demonstrated diffuse plasmacytoid cell proliferation in the alveolar spaces and interstitium. The plasma cells had fine chromatin with mild pleomorphism and mitotic activity without evidence of fibrosis or any other inflammatory cell infiltration. Immunohistochemistry (IHC) revealed diffuse reactivity with CD79a and CD138 and was negative for CD20 and cytokeratin (CK) (Figures 3 and 4).


Primary pulmonary plasmacytoma with diffuse alveolar consolidation: a case report.

Mohammad Taheri Z, Mohammadi F, Karbasi M, Seyfollahi L, Kahkoei S, Ghadiany M, Fayazi N, Mansouri D - Patholog Res Int (2010)

The proliferated cells showing strong positivity for CD138 in Immunohistochemistry staining.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2990464&req=5

fig4: The proliferated cells showing strong positivity for CD138 in Immunohistochemistry staining.
Mentions: Transbronchial lung biopsy was done and pathologic examination of the specimen demonstrated diffuse plasmacytoid cell proliferation in the alveolar spaces and interstitium. The plasma cells had fine chromatin with mild pleomorphism and mitotic activity without evidence of fibrosis or any other inflammatory cell infiltration. Immunohistochemistry (IHC) revealed diffuse reactivity with CD79a and CD138 and was negative for CD20 and cytokeratin (CK) (Figures 3 and 4).

Bottom Line: Solitary extramedullary plasmacytomas are plasma cell tumors that tend to develop in mucosa-associated lymphoid tissues including the sinonasal or nasopharyngeal regions.Primary plasmacytoma of the lung is exceedingly rare and often presents as a solitary mass or nodule in mid-lung or hilar areas and diagnosed after resection.Herein, we report a case of primary pulmonary plasmacytoma that presented with diffuse alveolar consolidation and diagnosed by transbronchial lung biopsy.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, National Research Institute of Tuberculosis and Lung Disease, Tehran 19569, Iran.

ABSTRACT
Solitary extramedullary plasmacytomas are plasma cell tumors that tend to develop in mucosa-associated lymphoid tissues including the sinonasal or nasopharyngeal regions. Primary plasmacytoma of the lung is exceedingly rare and often presents as a solitary mass or nodule in mid-lung or hilar areas and diagnosed after resection. Herein, we report a case of primary pulmonary plasmacytoma that presented with diffuse alveolar consolidation and diagnosed by transbronchial lung biopsy.

No MeSH data available.


Related in: MedlinePlus