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Mixed hepatoblastoma in a young male adult: a case report and literature review.

Fiaschetti V, Fiori R, Gaspari E, Crusco S, Simonetti G - Case Rep Med (2010)

Bottom Line: Most of these tumours arise in the embryo; hence it seems to be unusual that hepatoblastoma occurs in adults and is an exceptional cause of primary malignant liver tumour in adult patients.The diagnosis is often overlooked, and patients might be diagnosed at late stages of the disease at risk of increased mortality.The MRI detects tumor features as size, margins, and ratio with neighboring organs in order to get the best surgical approach.

View Article: PubMed Central - PubMed

Affiliation: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Policlinico Universitario "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.

ABSTRACT
Hepatoblastoma (HB) is a rare malignant tumour of the liver and usually occurs in the first three years of life. Most of these tumours arise in the embryo; hence it seems to be unusual that hepatoblastoma occurs in adults and is an exceptional cause of primary malignant liver tumour in adult patients. The diagnosis is often overlooked, and patients might be diagnosed at late stages of the disease at risk of increased mortality. In this paper we report a case of a 30-year-old man with mixed hepatoblastoma and abdominal pain, hepatomegaly and fever. The patient under went noninvasive diagnostic methods: duplex scanning, Computed Tomography (CT), and Magnetic Resonance imaging (MRI). In our experience, despite the important role of histological sample provided by biopsy in defining the diagnosis, very important was the role of MRI, more than ultrasonography and enhanced CT. The MRI detects tumor features as size, margins, and ratio with neighboring organs in order to get the best surgical approach.

No MeSH data available.


Related in: MedlinePlus

Microscopic examination of mass was composed by a combination of mesenchymal and epithelial elements. The surgical diagnosis confirmed the mixed hepatoblastoma.
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fig4: Microscopic examination of mass was composed by a combination of mesenchymal and epithelial elements. The surgical diagnosis confirmed the mixed hepatoblastoma.

Mentions: Subsequent diagnostic imaging phase, a bioptic sample was obtained with a CT-guided biopsy with 18 G tru-cut needle. Histopathologic examination revealed the presence of mesenchymal and epithelial cells in bioptic specimen and confirmed the diagnosis of a mixed hepatoblastoma (Figure 4).


Mixed hepatoblastoma in a young male adult: a case report and literature review.

Fiaschetti V, Fiori R, Gaspari E, Crusco S, Simonetti G - Case Rep Med (2010)

Microscopic examination of mass was composed by a combination of mesenchymal and epithelial elements. The surgical diagnosis confirmed the mixed hepatoblastoma.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2990241&req=5

fig4: Microscopic examination of mass was composed by a combination of mesenchymal and epithelial elements. The surgical diagnosis confirmed the mixed hepatoblastoma.
Mentions: Subsequent diagnostic imaging phase, a bioptic sample was obtained with a CT-guided biopsy with 18 G tru-cut needle. Histopathologic examination revealed the presence of mesenchymal and epithelial cells in bioptic specimen and confirmed the diagnosis of a mixed hepatoblastoma (Figure 4).

Bottom Line: Most of these tumours arise in the embryo; hence it seems to be unusual that hepatoblastoma occurs in adults and is an exceptional cause of primary malignant liver tumour in adult patients.The diagnosis is often overlooked, and patients might be diagnosed at late stages of the disease at risk of increased mortality.The MRI detects tumor features as size, margins, and ratio with neighboring organs in order to get the best surgical approach.

View Article: PubMed Central - PubMed

Affiliation: Dipartimento di Diagnostica per Immagini, Imaging Molecolare, Radiologia Interventistica e Radioterapia, Policlinico Universitario "Tor Vergata", Viale Oxford 81, 00133 Roma, Italy.

ABSTRACT
Hepatoblastoma (HB) is a rare malignant tumour of the liver and usually occurs in the first three years of life. Most of these tumours arise in the embryo; hence it seems to be unusual that hepatoblastoma occurs in adults and is an exceptional cause of primary malignant liver tumour in adult patients. The diagnosis is often overlooked, and patients might be diagnosed at late stages of the disease at risk of increased mortality. In this paper we report a case of a 30-year-old man with mixed hepatoblastoma and abdominal pain, hepatomegaly and fever. The patient under went noninvasive diagnostic methods: duplex scanning, Computed Tomography (CT), and Magnetic Resonance imaging (MRI). In our experience, despite the important role of histological sample provided by biopsy in defining the diagnosis, very important was the role of MRI, more than ultrasonography and enhanced CT. The MRI detects tumor features as size, margins, and ratio with neighboring organs in order to get the best surgical approach.

No MeSH data available.


Related in: MedlinePlus