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Implementation and validation of a commercial portal dosimetry software for intensity-modulated radiation therapy pre-treatment verification.

Varatharaj C, Moretti E, Ravikumar M, Malisan MR, Supe SS, Padovani R - J Med Phys (2010)

Bottom Line: The mean γ values are found to be 0.42 (SD: 0.06) and 0.44 (SD: 0.06) for the EPIDose and MapCHECK(™), respectively.The average γ∆ for EPIDose and MapCHECK(™) are found as 0.51 (SD: 0.06) and 0.53 (SD: 0.07), respectively.Based on our results obtained with EPIDose and strong agreement with MapCHECK(™), we may conclude that the EPIDose portal dosimetry system has been successfully implemented and validated with our routine 2D array detector.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Physics, University Hospital, Udine - 33100, India.

ABSTRACT
Electronic portal imaging devices (EPIDs) are extensively used for obtaining dosimetric information of pre-treatment field verification and in-vivo dosimetry for intensity-modulated radiotherapy (IMRT). In the present study, we have implemented the newly developed portal dosimetry software using independent dose prediction algorithm EPIDose(™) and evaluated this new tool for the pre-treatment IMRT plan quality assurance of Whole Pelvis with Simultaneous Integrated Boost (WP-SIB-IMRT) of prostate cases by comparing with routine two-dimensional (2D) array detector system (MapCHECK(™)). We have investigated 104 split fields using γ -distributions in terms of predefined γ frequency parameters. The mean γ values are found to be 0.42 (SD: 0.06) and 0.44 (SD: 0.06) for the EPIDose and MapCHECK(™), respectively. The average γ∆ for EPIDose and MapCHECK(™) are found as 0.51 (SD: 0.06) and 0.53 (SD: 0.07), respectively. Furthermore, the percentage of points with γ < 1, γ < 1.5, and γ > 2 are 97.4%, 99.3%, and 0.56%, respectively for EPIDose and 96.4%, 99.0% and 0.62% for MapCHECK(™). Based on our results obtained with EPIDose and strong agreement with MapCHECK(™), we may conclude that the EPIDose portal dosimetry system has been successfully implemented and validated with our routine 2D array detector.

No MeSH data available.


Related in: MedlinePlus

Linear regression analysis between MapCHECK and EPIDose in terms of percentage of points with γ < 1 using 3 mm and 3% criteria for the 104 analyzed fields. The dotted diagonal line represents the ideal match between the data. The inner legend shows the correlation equation and coefficient
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Figure 0005: Linear regression analysis between MapCHECK and EPIDose in terms of percentage of points with γ < 1 using 3 mm and 3% criteria for the 104 analyzed fields. The dotted diagonal line represents the ideal match between the data. The inner legend shows the correlation equation and coefficient

Mentions: We have quantified the agreement between the two dosimetric verification methods by determining the correlation of the two set of results. For statistical analysis, we applied the linear regression test by Pearson (SYSTAT 10, Systat Software, Inc., Chicago, IL, USA). Figures 4, 5, and 6 show the statistical analysis between the overall values obtained from the measurements of two detector systems in terms of mean γ, percentage of points with γ < 1 and γ < 1.5, respectively. The correlation coefficient were 0.949, 0.999, and 1.000, respectively for the repopulation of mean γ, percentage of points with γ < 1 and γ < 1.5.


Implementation and validation of a commercial portal dosimetry software for intensity-modulated radiation therapy pre-treatment verification.

Varatharaj C, Moretti E, Ravikumar M, Malisan MR, Supe SS, Padovani R - J Med Phys (2010)

Linear regression analysis between MapCHECK and EPIDose in terms of percentage of points with γ < 1 using 3 mm and 3% criteria for the 104 analyzed fields. The dotted diagonal line represents the ideal match between the data. The inner legend shows the correlation equation and coefficient
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2990112&req=5

Figure 0005: Linear regression analysis between MapCHECK and EPIDose in terms of percentage of points with γ < 1 using 3 mm and 3% criteria for the 104 analyzed fields. The dotted diagonal line represents the ideal match between the data. The inner legend shows the correlation equation and coefficient
Mentions: We have quantified the agreement between the two dosimetric verification methods by determining the correlation of the two set of results. For statistical analysis, we applied the linear regression test by Pearson (SYSTAT 10, Systat Software, Inc., Chicago, IL, USA). Figures 4, 5, and 6 show the statistical analysis between the overall values obtained from the measurements of two detector systems in terms of mean γ, percentage of points with γ < 1 and γ < 1.5, respectively. The correlation coefficient were 0.949, 0.999, and 1.000, respectively for the repopulation of mean γ, percentage of points with γ < 1 and γ < 1.5.

Bottom Line: The mean γ values are found to be 0.42 (SD: 0.06) and 0.44 (SD: 0.06) for the EPIDose and MapCHECK(™), respectively.The average γ∆ for EPIDose and MapCHECK(™) are found as 0.51 (SD: 0.06) and 0.53 (SD: 0.07), respectively.Based on our results obtained with EPIDose and strong agreement with MapCHECK(™), we may conclude that the EPIDose portal dosimetry system has been successfully implemented and validated with our routine 2D array detector.

View Article: PubMed Central - PubMed

Affiliation: Department of Medical Physics, University Hospital, Udine - 33100, India.

ABSTRACT
Electronic portal imaging devices (EPIDs) are extensively used for obtaining dosimetric information of pre-treatment field verification and in-vivo dosimetry for intensity-modulated radiotherapy (IMRT). In the present study, we have implemented the newly developed portal dosimetry software using independent dose prediction algorithm EPIDose(™) and evaluated this new tool for the pre-treatment IMRT plan quality assurance of Whole Pelvis with Simultaneous Integrated Boost (WP-SIB-IMRT) of prostate cases by comparing with routine two-dimensional (2D) array detector system (MapCHECK(™)). We have investigated 104 split fields using γ -distributions in terms of predefined γ frequency parameters. The mean γ values are found to be 0.42 (SD: 0.06) and 0.44 (SD: 0.06) for the EPIDose and MapCHECK(™), respectively. The average γ∆ for EPIDose and MapCHECK(™) are found as 0.51 (SD: 0.06) and 0.53 (SD: 0.07), respectively. Furthermore, the percentage of points with γ < 1, γ < 1.5, and γ > 2 are 97.4%, 99.3%, and 0.56%, respectively for EPIDose and 96.4%, 99.0% and 0.62% for MapCHECK(™). Based on our results obtained with EPIDose and strong agreement with MapCHECK(™), we may conclude that the EPIDose portal dosimetry system has been successfully implemented and validated with our routine 2D array detector.

No MeSH data available.


Related in: MedlinePlus