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Is Vibrio fluvialis emerging as a pathogen with epidemic potential in coastal region of eastern India following cyclone Aila?

Bhattacharjee S, Bhattacharjee S, Bal B, Pal R, Niyogi SK, Sarkar K - J Health Popul Nutr (2010)

Bottom Line: The attack rate and the severity of the cases were significantly higher in Pakhirala village compared to other affected villages.The laboratory results revealed that Vibrio fluvialis was the predominant pathogen in Pakhirala village (5 of 6 laboratory-confirmed organisms) whereas Vibrio cholerae O1 Ogawa was the predominant pathogen in other villages of Gosaba block (7 of 9 bacteriologically-confirmed organisms).This result indicates that V fluvialis behaves more aggressively than V cholerae O1 in an epidemic situation with a higher attack rate and a different clinical picture.

View Article: PubMed Central - PubMed

Affiliation: Tagore Society for Rural Development, Rangabelia, South 24 Parganas, India.

ABSTRACT
An isolated area with diarrhoea epidemic was explored at Pakhirala village of the Sundarbans, a coastal region of South 24 Parganas district of West Bengal, eastern India. The Pakhirala village was surrounded by other villages affected by a similar epidemic. The affected villages experienced this epidemic following the cyclone Aila, which had hit the coastal region of the Sundarbans in eastern India. In Pakhirala, the situation was the worst. Within a span of six weeks (5 June-20 July 2009), 3,529 (91.2%) of 3,871 residents were affected by watery diarrhoea. Of all the cases (n = 3,529), 918 (26%) were affected by moderate to severe diarrhoea. In other villages, 28,550 (70%) of the 40,786 people were affected; of them, 3,997 (14%) had moderate to severe watery diarrhoea. The attack rate and the severity of the cases were significantly higher in Pakhirala village compared to other affected villages. The laboratory results revealed that Vibrio fluvialis was the predominant pathogen in Pakhirala village (5 of 6 laboratory-confirmed organisms) whereas Vibrio cholerae O1 Ogawa was the predominant pathogen in other villages of Gosaba block (7 of 9 bacteriologically-confirmed organisms). This result indicates that V fluvialis behaves more aggressively than V cholerae O1 in an epidemic situation with a higher attack rate and a different clinical picture. An in-depth study is required to explore its pathogenicity in detail, geographical distribution, and possible control measures, including development of specific vaccine preparation and determination of its efficacy.

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Age and sex distribution of reported moderate to severe cases (n=100) at Pakhirala village, Gosaba block, Sundarbans area, 5 June–20 July 2009
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Figure 3: Age and sex distribution of reported moderate to severe cases (n=100) at Pakhirala village, Gosaba block, Sundarbans area, 5 June–20 July 2009

Mentions: Figure 3 shows age and sex distribution of the cases in Pakhirala village. The disease was distributed mostly in extremes of ages. Males and females appeared to be equally susceptible in all age-groups, except in the age-groups of 20-25 years and 35-40 years, where all the affected were female.


Is Vibrio fluvialis emerging as a pathogen with epidemic potential in coastal region of eastern India following cyclone Aila?

Bhattacharjee S, Bhattacharjee S, Bal B, Pal R, Niyogi SK, Sarkar K - J Health Popul Nutr (2010)

Age and sex distribution of reported moderate to severe cases (n=100) at Pakhirala village, Gosaba block, Sundarbans area, 5 June–20 July 2009
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2965321&req=5

Figure 3: Age and sex distribution of reported moderate to severe cases (n=100) at Pakhirala village, Gosaba block, Sundarbans area, 5 June–20 July 2009
Mentions: Figure 3 shows age and sex distribution of the cases in Pakhirala village. The disease was distributed mostly in extremes of ages. Males and females appeared to be equally susceptible in all age-groups, except in the age-groups of 20-25 years and 35-40 years, where all the affected were female.

Bottom Line: The attack rate and the severity of the cases were significantly higher in Pakhirala village compared to other affected villages.The laboratory results revealed that Vibrio fluvialis was the predominant pathogen in Pakhirala village (5 of 6 laboratory-confirmed organisms) whereas Vibrio cholerae O1 Ogawa was the predominant pathogen in other villages of Gosaba block (7 of 9 bacteriologically-confirmed organisms).This result indicates that V fluvialis behaves more aggressively than V cholerae O1 in an epidemic situation with a higher attack rate and a different clinical picture.

View Article: PubMed Central - PubMed

Affiliation: Tagore Society for Rural Development, Rangabelia, South 24 Parganas, India.

ABSTRACT
An isolated area with diarrhoea epidemic was explored at Pakhirala village of the Sundarbans, a coastal region of South 24 Parganas district of West Bengal, eastern India. The Pakhirala village was surrounded by other villages affected by a similar epidemic. The affected villages experienced this epidemic following the cyclone Aila, which had hit the coastal region of the Sundarbans in eastern India. In Pakhirala, the situation was the worst. Within a span of six weeks (5 June-20 July 2009), 3,529 (91.2%) of 3,871 residents were affected by watery diarrhoea. Of all the cases (n = 3,529), 918 (26%) were affected by moderate to severe diarrhoea. In other villages, 28,550 (70%) of the 40,786 people were affected; of them, 3,997 (14%) had moderate to severe watery diarrhoea. The attack rate and the severity of the cases were significantly higher in Pakhirala village compared to other affected villages. The laboratory results revealed that Vibrio fluvialis was the predominant pathogen in Pakhirala village (5 of 6 laboratory-confirmed organisms) whereas Vibrio cholerae O1 Ogawa was the predominant pathogen in other villages of Gosaba block (7 of 9 bacteriologically-confirmed organisms). This result indicates that V fluvialis behaves more aggressively than V cholerae O1 in an epidemic situation with a higher attack rate and a different clinical picture. An in-depth study is required to explore its pathogenicity in detail, geographical distribution, and possible control measures, including development of specific vaccine preparation and determination of its efficacy.

Show MeSH
Related in: MedlinePlus