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Investigating an airborne tularemia outbreak, Germany.

Hauri AM, Hofstetter I, Seibold E, Kaysser P, Eckert J, Neubauer H, Splettstoesser WD - Emerging Infect. Dis. (2010)

Bottom Line: Previously reported tularemia outbreaks in Germany dated back to the 1950s.Swabs taken at the game chamber and water samples were PCR negative for F. tularensis.Eleven of 14 hare parts showed low-level concentrations of F. tularensis, compatible with cross-contamination.

View Article: PubMed Central - PubMed

Affiliation: Hesse State Health Office, Dillenburg, Germany. anja.hauri@hlpug.hessen.de

ABSTRACT
In November 2005, an outbreak of tularemia occurred among 39 participants in a hare hunt in Hesse, Germany. Previously reported tularemia outbreaks in Germany dated back to the 1950s. We conducted a retrospective cohort study among participants and investigated the environment to identify risk factors for infection. Ten participants had serologic evidence of acute Francisella tularensis infection; 1 other participant died before laboratory confirmation was obtained. Presence within 5 meters of the place where disemboweled hares were rinsed with a water hose was the risk factor most strongly associated with infection (risk ratio 22.1; 95% confidence interval 13.2-154.3). Swabs taken at the game chamber and water samples were PCR negative for F. tularensis. Eleven of 14 hare parts showed low-level concentrations of F. tularensis, compatible with cross-contamination. More than half of case-patients may have acquired infection through inhalation of aerosolized droplets containing F. tularensis generated during rinsing of infected hares.

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Related in: MedlinePlus

Sampling at the game chamber, Hesse, Germany, December 2005.
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Related In: Results  -  Collection


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Figure 1: Sampling at the game chamber, Hesse, Germany, December 2005.

Mentions: Starting in early December 2005, we visited the outbreak area 3 times. We obtained data on elevation, regional mean annual air temperature, precipitation, and sunshine hours (1961–2004) from the Federal Meteorological Service (Offenbach am Main, Germany). Water samples were obtained from a small creek near the hunting lodge and from the water hose used to rinse disemboweled hares. Additionally, 28 samples were taken at the game chamber (Table 1; Figure 1). All samples were stored at 4°C.


Investigating an airborne tularemia outbreak, Germany.

Hauri AM, Hofstetter I, Seibold E, Kaysser P, Eckert J, Neubauer H, Splettstoesser WD - Emerging Infect. Dis. (2010)

Sampling at the game chamber, Hesse, Germany, December 2005.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2957990&req=5

Figure 1: Sampling at the game chamber, Hesse, Germany, December 2005.
Mentions: Starting in early December 2005, we visited the outbreak area 3 times. We obtained data on elevation, regional mean annual air temperature, precipitation, and sunshine hours (1961–2004) from the Federal Meteorological Service (Offenbach am Main, Germany). Water samples were obtained from a small creek near the hunting lodge and from the water hose used to rinse disemboweled hares. Additionally, 28 samples were taken at the game chamber (Table 1; Figure 1). All samples were stored at 4°C.

Bottom Line: Previously reported tularemia outbreaks in Germany dated back to the 1950s.Swabs taken at the game chamber and water samples were PCR negative for F. tularensis.Eleven of 14 hare parts showed low-level concentrations of F. tularensis, compatible with cross-contamination.

View Article: PubMed Central - PubMed

Affiliation: Hesse State Health Office, Dillenburg, Germany. anja.hauri@hlpug.hessen.de

ABSTRACT
In November 2005, an outbreak of tularemia occurred among 39 participants in a hare hunt in Hesse, Germany. Previously reported tularemia outbreaks in Germany dated back to the 1950s. We conducted a retrospective cohort study among participants and investigated the environment to identify risk factors for infection. Ten participants had serologic evidence of acute Francisella tularensis infection; 1 other participant died before laboratory confirmation was obtained. Presence within 5 meters of the place where disemboweled hares were rinsed with a water hose was the risk factor most strongly associated with infection (risk ratio 22.1; 95% confidence interval 13.2-154.3). Swabs taken at the game chamber and water samples were PCR negative for F. tularensis. Eleven of 14 hare parts showed low-level concentrations of F. tularensis, compatible with cross-contamination. More than half of case-patients may have acquired infection through inhalation of aerosolized droplets containing F. tularensis generated during rinsing of infected hares.

Show MeSH
Related in: MedlinePlus