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Clonal distribution of invasive pneumococci, Czech Republic, 1996-2003.

Zemlickova H, Urbaskova P, Jakubu V, Motlova J, Musilek M, Prochazka B - Emerging Infect. Dis. (2010)

Bottom Line: We conducted surveillance on invasive pneumococci isolated from adults in the Czech Republic during 1996-2003.The 7 most prevalent serotypes were characterized.Coverage with the 7-valent pneumococcal conjugate vaccine was low.

View Article: PubMed Central - PubMed

Affiliation: National Institute of Public Health, Prague, Czech Republic.

ABSTRACT
We conducted surveillance on invasive pneumococci isolated from adults in the Czech Republic during 1996-2003. The 7 most prevalent serotypes were characterized. Coverage with the 7-valent pneumococcal conjugate vaccine was low. Our observations confirm that detection methods may have modified the expected effect of this vaccine.

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Related in: MedlinePlus

A) Invasive pneumococcal isolates from blood and cerebrospinal fluid (CSF) and B) frequency of Streptococcus pneumoniae serotypes 1, 3, and 4 among adults, Czech Republic, 1996–2003.
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Figure 1: A) Invasive pneumococcal isolates from blood and cerebrospinal fluid (CSF) and B) frequency of Streptococcus pneumoniae serotypes 1, 3, and 4 among adults, Czech Republic, 1996–2003.

Mentions: During 1996–2003, a total of 446 (64.7%) isolates were obtained from adults 18–64 years of age and 243 (35.3%) isolates were obtained from adults >65 years of age. A progressive increase in recovery of isolates from blood was observed from 44 during 1996–1997 to 199 during 2002–2003 (p = 0.009) (Figure 1). Serotyping identified 48 serotypes; 10 of these serotypes included >30 isolates. Half of all strains belonged to serotypes 3 (12.7%), 4 (8.6%), 8 (7%), 1 (5.8%), 19F (5.5%), 14 (5.5%), and 9V (5.2%) (Figure 2). Serotype coverage rates by PCV7, PCV10, PCV13, and 23-valent polysaccharide vaccine were 32.5%, 44.2%, 62.3%, and 82.1%, respectively, among adults 18–64 years of age and 35.4%, 42.8%, 61.3%, and 85.6%, respectively, among adults >65 years of age.


Clonal distribution of invasive pneumococci, Czech Republic, 1996-2003.

Zemlickova H, Urbaskova P, Jakubu V, Motlova J, Musilek M, Prochazka B - Emerging Infect. Dis. (2010)

A) Invasive pneumococcal isolates from blood and cerebrospinal fluid (CSF) and B) frequency of Streptococcus pneumoniae serotypes 1, 3, and 4 among adults, Czech Republic, 1996–2003.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2957987&req=5

Figure 1: A) Invasive pneumococcal isolates from blood and cerebrospinal fluid (CSF) and B) frequency of Streptococcus pneumoniae serotypes 1, 3, and 4 among adults, Czech Republic, 1996–2003.
Mentions: During 1996–2003, a total of 446 (64.7%) isolates were obtained from adults 18–64 years of age and 243 (35.3%) isolates were obtained from adults >65 years of age. A progressive increase in recovery of isolates from blood was observed from 44 during 1996–1997 to 199 during 2002–2003 (p = 0.009) (Figure 1). Serotyping identified 48 serotypes; 10 of these serotypes included >30 isolates. Half of all strains belonged to serotypes 3 (12.7%), 4 (8.6%), 8 (7%), 1 (5.8%), 19F (5.5%), 14 (5.5%), and 9V (5.2%) (Figure 2). Serotype coverage rates by PCV7, PCV10, PCV13, and 23-valent polysaccharide vaccine were 32.5%, 44.2%, 62.3%, and 82.1%, respectively, among adults 18–64 years of age and 35.4%, 42.8%, 61.3%, and 85.6%, respectively, among adults >65 years of age.

Bottom Line: We conducted surveillance on invasive pneumococci isolated from adults in the Czech Republic during 1996-2003.The 7 most prevalent serotypes were characterized.Coverage with the 7-valent pneumococcal conjugate vaccine was low.

View Article: PubMed Central - PubMed

Affiliation: National Institute of Public Health, Prague, Czech Republic.

ABSTRACT
We conducted surveillance on invasive pneumococci isolated from adults in the Czech Republic during 1996-2003. The 7 most prevalent serotypes were characterized. Coverage with the 7-valent pneumococcal conjugate vaccine was low. Our observations confirm that detection methods may have modified the expected effect of this vaccine.

Show MeSH
Related in: MedlinePlus