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Uncontrolled asthma: assessing quality of life and productivity of children and their caregivers using a cross-sectional Internet-based survey.

Dean BB, Calimlim BC, Sacco P, Aguilar D, Maykut R, Tinkelman D - Health Qual Life Outcomes (2010)

Bottom Line: Children's health-related quality of life (HRQOL) and caregivers' quality of life (QOL) were assessed using the Child Health Questionnaire Parent Form 28 (CHQ-PF28) and caregiver's work productivity using a modified Work Productivity and Activity Impairment Questionnaire.They were more likely to miss school (5.5 vs 2.2 days), arrive late or leave early (26.7 vs 7.1%), miss school-related activities (40.6 vs 6.2%), use a rescue inhaler at school (64.2 vs 31.0%), and visit the health office or school nurse (22.5 vs 8.8%).Caregivers of children with uncontrolled asthma reported significantly greater work and activity impairment and lower QOL for emotional, time-related and family activities.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cerner LifeSciences, Beverly Hills, CA, USA. bdean@cerner.com

ABSTRACT

Background: Results of a national survey of asthmatic children that evaluated management goals established in 2004 by the National Asthma Education and Prevention Program (NAEPP) indicated that asthma symptom control fell short on nearly every goal.

Methods: An Internet-based survey was administered to adult caregivers of children aged 6-12 years with moderate to severe asthma. Asthma was categorized as uncontrolled when the caregiver reported pre-specified criteria for daytime symptoms, nighttime awakening, activity limitation, or rescue medication based on the NAEPP guidelines. Children's health-related quality of life (HRQOL) and caregivers' quality of life (QOL) were assessed using the Child Health Questionnaire Parent Form 28 (CHQ-PF28) and caregiver's work productivity using a modified Work Productivity and Activity Impairment Questionnaire. Children with uncontrolled vs. controlled asthma were compared.

Results: 360 caregivers of children with uncontrolled asthma and 113 of children with controlled asthma completed the survey. Children with uncontrolled asthma had significantly lower CHQ-PF28 physical (mean 38.1 vs 49.8, uncontrolled vs controlled, respectively) and psychosocial (48.2 vs 53.8) summary measure scores. They were more likely to miss school (5.5 vs 2.2 days), arrive late or leave early (26.7 vs 7.1%), miss school-related activities (40.6 vs 6.2%), use a rescue inhaler at school (64.2 vs 31.0%), and visit the health office or school nurse (22.5 vs 8.8%). Caregivers of children with uncontrolled asthma reported significantly greater work and activity impairment and lower QOL for emotional, time-related and family activities.

Conclusions: Poorly controlled asthma symptoms impair HRQOL of children, QOL of their caregivers, and productivity of both. Proper treatment and management to improve symptom control may reduce humanistic and economic burdens on asthmatic children and their caregivers.

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Related in: MedlinePlus

CHQ-PF28 Scores by Asthma Symptom Control. All values are displayed as mean (SD). ‡P ≤ 0.005. §P ≤ 0.0001
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Figure 2: CHQ-PF28 Scores by Asthma Symptom Control. All values are displayed as mean (SD). ‡P ≤ 0.005. §P ≤ 0.0001

Mentions: Among the nine domains evaluating the HRQOL of the child, children with uncontrolled asthma had significantly worse CHQ-PF28 measures across seven (PF, REB, RP, BP, BE, MH, and SE) when compared with children with controlled asthma (Figure 2). No significant difference was observed in the remaining two scales of change in health and general health. Significant differences were observed in both summary measures; lower mean physical and psychosocial summary measure scores were observed for children with uncontrolled asthma as compared to those whose asthma was controlled by 11.7 points (SE = 1.2, RS = 2.4) and 5.6 points (SE = 1.1, RS = 0.7), respectively (Figure 2). Standardized mean summary scores for children with controlled asthma were within the expected range of population norms (mean = 50, SD = 10) and were within the range for most domains of those scores reported for a large sample of children with no conditions. The mean physical summary scale score for children with uncontrolled asthma was greater than one standard deviation below expected population norms.


Uncontrolled asthma: assessing quality of life and productivity of children and their caregivers using a cross-sectional Internet-based survey.

Dean BB, Calimlim BC, Sacco P, Aguilar D, Maykut R, Tinkelman D - Health Qual Life Outcomes (2010)

CHQ-PF28 Scores by Asthma Symptom Control. All values are displayed as mean (SD). ‡P ≤ 0.005. §P ≤ 0.0001
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2944345&req=5

Figure 2: CHQ-PF28 Scores by Asthma Symptom Control. All values are displayed as mean (SD). ‡P ≤ 0.005. §P ≤ 0.0001
Mentions: Among the nine domains evaluating the HRQOL of the child, children with uncontrolled asthma had significantly worse CHQ-PF28 measures across seven (PF, REB, RP, BP, BE, MH, and SE) when compared with children with controlled asthma (Figure 2). No significant difference was observed in the remaining two scales of change in health and general health. Significant differences were observed in both summary measures; lower mean physical and psychosocial summary measure scores were observed for children with uncontrolled asthma as compared to those whose asthma was controlled by 11.7 points (SE = 1.2, RS = 2.4) and 5.6 points (SE = 1.1, RS = 0.7), respectively (Figure 2). Standardized mean summary scores for children with controlled asthma were within the expected range of population norms (mean = 50, SD = 10) and were within the range for most domains of those scores reported for a large sample of children with no conditions. The mean physical summary scale score for children with uncontrolled asthma was greater than one standard deviation below expected population norms.

Bottom Line: Children's health-related quality of life (HRQOL) and caregivers' quality of life (QOL) were assessed using the Child Health Questionnaire Parent Form 28 (CHQ-PF28) and caregiver's work productivity using a modified Work Productivity and Activity Impairment Questionnaire.They were more likely to miss school (5.5 vs 2.2 days), arrive late or leave early (26.7 vs 7.1%), miss school-related activities (40.6 vs 6.2%), use a rescue inhaler at school (64.2 vs 31.0%), and visit the health office or school nurse (22.5 vs 8.8%).Caregivers of children with uncontrolled asthma reported significantly greater work and activity impairment and lower QOL for emotional, time-related and family activities.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cerner LifeSciences, Beverly Hills, CA, USA. bdean@cerner.com

ABSTRACT

Background: Results of a national survey of asthmatic children that evaluated management goals established in 2004 by the National Asthma Education and Prevention Program (NAEPP) indicated that asthma symptom control fell short on nearly every goal.

Methods: An Internet-based survey was administered to adult caregivers of children aged 6-12 years with moderate to severe asthma. Asthma was categorized as uncontrolled when the caregiver reported pre-specified criteria for daytime symptoms, nighttime awakening, activity limitation, or rescue medication based on the NAEPP guidelines. Children's health-related quality of life (HRQOL) and caregivers' quality of life (QOL) were assessed using the Child Health Questionnaire Parent Form 28 (CHQ-PF28) and caregiver's work productivity using a modified Work Productivity and Activity Impairment Questionnaire. Children with uncontrolled vs. controlled asthma were compared.

Results: 360 caregivers of children with uncontrolled asthma and 113 of children with controlled asthma completed the survey. Children with uncontrolled asthma had significantly lower CHQ-PF28 physical (mean 38.1 vs 49.8, uncontrolled vs controlled, respectively) and psychosocial (48.2 vs 53.8) summary measure scores. They were more likely to miss school (5.5 vs 2.2 days), arrive late or leave early (26.7 vs 7.1%), miss school-related activities (40.6 vs 6.2%), use a rescue inhaler at school (64.2 vs 31.0%), and visit the health office or school nurse (22.5 vs 8.8%). Caregivers of children with uncontrolled asthma reported significantly greater work and activity impairment and lower QOL for emotional, time-related and family activities.

Conclusions: Poorly controlled asthma symptoms impair HRQOL of children, QOL of their caregivers, and productivity of both. Proper treatment and management to improve symptom control may reduce humanistic and economic burdens on asthmatic children and their caregivers.

Show MeSH
Related in: MedlinePlus