Limits...
Central odontogenic fibroma: a case report with long-term follow-up.

Brazão-Silva MT, Fernandes AV, Durighetto-Júnior AF, Cardoso SV, Loyola AM - Head Face Med (2010)

Bottom Line: An osteolytic tumour of the mandible with prominent expansive growth on the alveolar ridge and displacement of the involved teeth is described in a 28-year-old man.The lesion was diagnosed as a central odontogenic fibroma, an uncommon benign neoplasm derived from dental apparatus, and was removed by curettage.The patient remains asymptomatic after thirteen years of follow-up, which supports the claimed indolent behavior of this poorly documented disease and the adequacy of a conservative surgical treatment.

View Article: PubMed Central - HTML - PubMed

Affiliation: General Pathology master degree program, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.

ABSTRACT
An osteolytic tumour of the mandible with prominent expansive growth on the alveolar ridge and displacement of the involved teeth is described in a 28-year-old man. The lesion was diagnosed as a central odontogenic fibroma, an uncommon benign neoplasm derived from dental apparatus, and was removed by curettage. The patient remains asymptomatic after thirteen years of follow-up, which supports the claimed indolent behavior of this poorly documented disease and the adequacy of a conservative surgical treatment.

Show MeSH

Related in: MedlinePlus

Microscopic view demonstrating a lesion constituted by fibrous connective tissue and abundant nests and strands of inactive-looking OE usually surrounded by basophilic extra-cellular substance (1000×, hematoxilin-eosin).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC2927520&req=5

Figure 2: Microscopic view demonstrating a lesion constituted by fibrous connective tissue and abundant nests and strands of inactive-looking OE usually surrounded by basophilic extra-cellular substance (1000×, hematoxilin-eosin).

Mentions: Microscopically, the sample consisted in a fibrous connective tissue alternated with more vacuolated myxomatous areas. Individual nuclear morphology of the fibroblasts varied from spindle shaped to stellate. Abundant nests and strands of odontogenic epithelium were found, often with a clear or vacuolated cytoplasm, sometimes surrounded by juxtaepithelial hyalinization (Figure 2). Calcification, inflammatory cells and mitotic activity were not observed. Correlation of clinical, radiographic and histopathological features leaded to the diagnosis of central odontogenic fibroma.


Central odontogenic fibroma: a case report with long-term follow-up.

Brazão-Silva MT, Fernandes AV, Durighetto-Júnior AF, Cardoso SV, Loyola AM - Head Face Med (2010)

Microscopic view demonstrating a lesion constituted by fibrous connective tissue and abundant nests and strands of inactive-looking OE usually surrounded by basophilic extra-cellular substance (1000×, hematoxilin-eosin).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2927520&req=5

Figure 2: Microscopic view demonstrating a lesion constituted by fibrous connective tissue and abundant nests and strands of inactive-looking OE usually surrounded by basophilic extra-cellular substance (1000×, hematoxilin-eosin).
Mentions: Microscopically, the sample consisted in a fibrous connective tissue alternated with more vacuolated myxomatous areas. Individual nuclear morphology of the fibroblasts varied from spindle shaped to stellate. Abundant nests and strands of odontogenic epithelium were found, often with a clear or vacuolated cytoplasm, sometimes surrounded by juxtaepithelial hyalinization (Figure 2). Calcification, inflammatory cells and mitotic activity were not observed. Correlation of clinical, radiographic and histopathological features leaded to the diagnosis of central odontogenic fibroma.

Bottom Line: An osteolytic tumour of the mandible with prominent expansive growth on the alveolar ridge and displacement of the involved teeth is described in a 28-year-old man.The lesion was diagnosed as a central odontogenic fibroma, an uncommon benign neoplasm derived from dental apparatus, and was removed by curettage.The patient remains asymptomatic after thirteen years of follow-up, which supports the claimed indolent behavior of this poorly documented disease and the adequacy of a conservative surgical treatment.

View Article: PubMed Central - HTML - PubMed

Affiliation: General Pathology master degree program, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil.

ABSTRACT
An osteolytic tumour of the mandible with prominent expansive growth on the alveolar ridge and displacement of the involved teeth is described in a 28-year-old man. The lesion was diagnosed as a central odontogenic fibroma, an uncommon benign neoplasm derived from dental apparatus, and was removed by curettage. The patient remains asymptomatic after thirteen years of follow-up, which supports the claimed indolent behavior of this poorly documented disease and the adequacy of a conservative surgical treatment.

Show MeSH
Related in: MedlinePlus