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Listening for recollection: a multi-voxel pattern analysis of recognition memory retrieval strategies.

Quamme JR, Weiss DJ, Norman KA - Front Hum Neurosci (2010)

Bottom Line: We looked for brain regions that met the following criteria: (1) Distinct neural patterns should be present when subjects are instructed to rely on recollection vs. familiarity, and (2) fluctuations in these neural patterns should be related to recognition behavior in the manner predicted by dual-process theories of recognition: Specifically, the presence of the recollection pattern during the pre-stimulus interval (indicating that subjects are "listening for recollection" at that moment) should be associated with a selective decrease in false alarms to related lures.We found that pre-stimulus activity in the right supramarginal gyrus met all of these criteria, suggesting that this region proactively establishes an internally directed attentional state that fosters recollection.We also found other regions (e.g., left middle temporal gyrus) where the pattern of neural activity was related to subjects' responding to related lures after stimulus onset (but not before), suggesting that these regions implement processes that are engaged in a reactive fashion to boost recollection.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychology, Grand Valley State University Allendale, MI, USA.

ABSTRACT
Recent studies of recognition memory indicate that subjects can strategically vary how much they rely on recollection of specific details vs. feelings of familiarity when making recognition judgments. One possible explanation of these results is that subjects can establish an internally directed attentional state ("listening for recollection") that enhances retrieval of studied details; fluctuations in this attentional state over time should be associated with fluctuations in subjects' recognition behavior. In this study, we used multi-voxel pattern analysis of fMRI data to identify brain regions that are involved in listening for recollection. We looked for brain regions that met the following criteria: (1) Distinct neural patterns should be present when subjects are instructed to rely on recollection vs. familiarity, and (2) fluctuations in these neural patterns should be related to recognition behavior in the manner predicted by dual-process theories of recognition: Specifically, the presence of the recollection pattern during the pre-stimulus interval (indicating that subjects are "listening for recollection" at that moment) should be associated with a selective decrease in false alarms to related lures. We found that pre-stimulus activity in the right supramarginal gyrus met all of these criteria, suggesting that this region proactively establishes an internally directed attentional state that fosters recollection. We also found other regions (e.g., left middle temporal gyrus) where the pattern of neural activity was related to subjects' responding to related lures after stimulus onset (but not before), suggesting that these regions implement processes that are engaged in a reactive fashion to boost recollection.

No MeSH data available.


Related in: MedlinePlus

Classifier output as a function of recognition behavior in the right supramarginal gyrus/BA 40 for four time windows around the trial onset. The values shown here were computed by averaging classifier output from all of the spheres belonging to the cluster. The left panel shows MVPA results and the right panel shows AVG results. Each panel shows DRL (the classifier output difference for related-lure correct rejections vs. false alarms) in red and DSTUDIED (the classifier output difference for studied-item misses vs. hits) in blue. For both measures, positive values indicate greater use of recollection (according to the classifier) for “no” responses (correct rejections and misses) than for “yes” responses (false alarms and hits). Asterisks indicate time windows where the relationship between classifier output and behavior was significant (according to the non-parametric statistical tests described in the text). Error bars show the standard error of the mean across subjects.
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Figure 6: Classifier output as a function of recognition behavior in the right supramarginal gyrus/BA 40 for four time windows around the trial onset. The values shown here were computed by averaging classifier output from all of the spheres belonging to the cluster. The left panel shows MVPA results and the right panel shows AVG results. Each panel shows DRL (the classifier output difference for related-lure correct rejections vs. false alarms) in red and DSTUDIED (the classifier output difference for studied-item misses vs. hits) in blue. For both measures, positive values indicate greater use of recollection (according to the classifier) for “no” responses (correct rejections and misses) than for “yes” responses (false alarms and hits). Asterisks indicate time windows where the relationship between classifier output and behavior was significant (according to the non-parametric statistical tests described in the text). Error bars show the standard error of the mean across subjects.

Mentions: The significant MVPA effect in the right supramarginal gyrus is illustrated in Figure 6. The figure consists of two panels, with MVPA on the left and AVG analysis on the right. Each panel plots the mean DRL value (the difference in classifier output for related lure correct rejections and false alarms) and DSTUDIED value (the difference in classifier output for misses and hits) across spheres in the significant cluster. All metrics are plotted across each of the four time windows. The figure shows that, for the Window 1 MVPA analysis, DRL was well above 0 (indicating that use of recollection, as indexed by the classifier, was greater for related-lure correct rejections than false alarms) but DSTUDIED was close to 0 (indicating that use of recollection, as indexed by the classifier, was similar for misses and hits). The same qualitative pattern was also present for Window 2 in the MVPA analysis, but it did not reach significance.


Listening for recollection: a multi-voxel pattern analysis of recognition memory retrieval strategies.

Quamme JR, Weiss DJ, Norman KA - Front Hum Neurosci (2010)

Classifier output as a function of recognition behavior in the right supramarginal gyrus/BA 40 for four time windows around the trial onset. The values shown here were computed by averaging classifier output from all of the spheres belonging to the cluster. The left panel shows MVPA results and the right panel shows AVG results. Each panel shows DRL (the classifier output difference for related-lure correct rejections vs. false alarms) in red and DSTUDIED (the classifier output difference for studied-item misses vs. hits) in blue. For both measures, positive values indicate greater use of recollection (according to the classifier) for “no” responses (correct rejections and misses) than for “yes” responses (false alarms and hits). Asterisks indicate time windows where the relationship between classifier output and behavior was significant (according to the non-parametric statistical tests described in the text). Error bars show the standard error of the mean across subjects.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2927239&req=5

Figure 6: Classifier output as a function of recognition behavior in the right supramarginal gyrus/BA 40 for four time windows around the trial onset. The values shown here were computed by averaging classifier output from all of the spheres belonging to the cluster. The left panel shows MVPA results and the right panel shows AVG results. Each panel shows DRL (the classifier output difference for related-lure correct rejections vs. false alarms) in red and DSTUDIED (the classifier output difference for studied-item misses vs. hits) in blue. For both measures, positive values indicate greater use of recollection (according to the classifier) for “no” responses (correct rejections and misses) than for “yes” responses (false alarms and hits). Asterisks indicate time windows where the relationship between classifier output and behavior was significant (according to the non-parametric statistical tests described in the text). Error bars show the standard error of the mean across subjects.
Mentions: The significant MVPA effect in the right supramarginal gyrus is illustrated in Figure 6. The figure consists of two panels, with MVPA on the left and AVG analysis on the right. Each panel plots the mean DRL value (the difference in classifier output for related lure correct rejections and false alarms) and DSTUDIED value (the difference in classifier output for misses and hits) across spheres in the significant cluster. All metrics are plotted across each of the four time windows. The figure shows that, for the Window 1 MVPA analysis, DRL was well above 0 (indicating that use of recollection, as indexed by the classifier, was greater for related-lure correct rejections than false alarms) but DSTUDIED was close to 0 (indicating that use of recollection, as indexed by the classifier, was similar for misses and hits). The same qualitative pattern was also present for Window 2 in the MVPA analysis, but it did not reach significance.

Bottom Line: We looked for brain regions that met the following criteria: (1) Distinct neural patterns should be present when subjects are instructed to rely on recollection vs. familiarity, and (2) fluctuations in these neural patterns should be related to recognition behavior in the manner predicted by dual-process theories of recognition: Specifically, the presence of the recollection pattern during the pre-stimulus interval (indicating that subjects are "listening for recollection" at that moment) should be associated with a selective decrease in false alarms to related lures.We found that pre-stimulus activity in the right supramarginal gyrus met all of these criteria, suggesting that this region proactively establishes an internally directed attentional state that fosters recollection.We also found other regions (e.g., left middle temporal gyrus) where the pattern of neural activity was related to subjects' responding to related lures after stimulus onset (but not before), suggesting that these regions implement processes that are engaged in a reactive fashion to boost recollection.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychology, Grand Valley State University Allendale, MI, USA.

ABSTRACT
Recent studies of recognition memory indicate that subjects can strategically vary how much they rely on recollection of specific details vs. feelings of familiarity when making recognition judgments. One possible explanation of these results is that subjects can establish an internally directed attentional state ("listening for recollection") that enhances retrieval of studied details; fluctuations in this attentional state over time should be associated with fluctuations in subjects' recognition behavior. In this study, we used multi-voxel pattern analysis of fMRI data to identify brain regions that are involved in listening for recollection. We looked for brain regions that met the following criteria: (1) Distinct neural patterns should be present when subjects are instructed to rely on recollection vs. familiarity, and (2) fluctuations in these neural patterns should be related to recognition behavior in the manner predicted by dual-process theories of recognition: Specifically, the presence of the recollection pattern during the pre-stimulus interval (indicating that subjects are "listening for recollection" at that moment) should be associated with a selective decrease in false alarms to related lures. We found that pre-stimulus activity in the right supramarginal gyrus met all of these criteria, suggesting that this region proactively establishes an internally directed attentional state that fosters recollection. We also found other regions (e.g., left middle temporal gyrus) where the pattern of neural activity was related to subjects' responding to related lures after stimulus onset (but not before), suggesting that these regions implement processes that are engaged in a reactive fashion to boost recollection.

No MeSH data available.


Related in: MedlinePlus