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Prevalence, detection, and management of the metabolic syndrome in patients with acute myocardial infarction: role of an obesity-centric definition.

Prasad SB, Fahrtash F, Malaiapan Y, Meredith IT, Cameron J - Cardiol Res Pract (2010)

Bottom Line: Results.Conclusion.Despite the high prevalence, MS was under-recognized and under-treated in this population.

View Article: PubMed Central - PubMed

Affiliation: Monash Heart and Monash Cardiovascular Research Centre, Monash Medical Centre, 246 Clayton Road, Clayton, Melbourne, Victoria 3168, Australia.

ABSTRACT
Background. We sought to determine and compare the prevalence of the Metabolic Syndrome (MS) in patients with acute myocardial infarction (AMI) utilizing the new International Diabetes Federation (IDF) definition with the older National Cholesterol Education Program (NCEP) definition. We also examined the clinical utility of MS in this context. Methods. A total of 107 consecutive patients with AMI were prospectively evaluated for MS. Fasting lipids obtained at admission and fasting glucose at discharge were used. A postdischarge folder audit verified rates of discharge coding and implementation of specific management strategies for MS. Results. Baseline patient characteristics included: mean age 59 +/- 13 years; males 80%; diabetes 19%; mean BMI 29.7 +/- 8.4 kg/m(2). MS prevalence was 54% by the IDF definition and 49% by the NCEP definition, with good agreement between definitions: kappa = 0.664, P < .001. Factors predictive of MS after multivariate analysis included: hypertension, fasting glucose, waist circumference, and serum HDL (all P < .05). Despite the high prevalence, MS was recognized at discharge in only 1 patient, and referral for exercise and/or weight-loss programs was undertaken in 5 patients. Conclusion. There is a high prevalence of MS utilizing contemporary definitions in patients with AMI: 54% by the IDF definition and 49% by NCEP criteria. Despite the high prevalence, MS was under-recognized and under-treated in this population.

No MeSH data available.


Related in: MedlinePlus

Prevalence of the metabolic syndrome according to different definitions.
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Related In: Results  -  Collection


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fig1: Prevalence of the metabolic syndrome according to different definitions.

Mentions: The agreement between definitions for the presence of MS is illustrated in Figure 1. Out of the 64 patients (60%) who had MS by either definition, 46 patients (72%) had MS by both definitions, 12 patients (19%) had MS by the IDF definition only, and 6 patients (9%) had MS by the NCEP definition only. The number of patients without MS by either definition was 43 (40%). Cohen's Kappa for the agreement between the 2 definitions for the presence of MS was κ = 0.664, P < .001, suggestive of a moderately high degree of agreement between these two contemporary definitions.


Prevalence, detection, and management of the metabolic syndrome in patients with acute myocardial infarction: role of an obesity-centric definition.

Prasad SB, Fahrtash F, Malaiapan Y, Meredith IT, Cameron J - Cardiol Res Pract (2010)

Prevalence of the metabolic syndrome according to different definitions.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2926676&req=5

fig1: Prevalence of the metabolic syndrome according to different definitions.
Mentions: The agreement between definitions for the presence of MS is illustrated in Figure 1. Out of the 64 patients (60%) who had MS by either definition, 46 patients (72%) had MS by both definitions, 12 patients (19%) had MS by the IDF definition only, and 6 patients (9%) had MS by the NCEP definition only. The number of patients without MS by either definition was 43 (40%). Cohen's Kappa for the agreement between the 2 definitions for the presence of MS was κ = 0.664, P < .001, suggestive of a moderately high degree of agreement between these two contemporary definitions.

Bottom Line: Results.Conclusion.Despite the high prevalence, MS was under-recognized and under-treated in this population.

View Article: PubMed Central - PubMed

Affiliation: Monash Heart and Monash Cardiovascular Research Centre, Monash Medical Centre, 246 Clayton Road, Clayton, Melbourne, Victoria 3168, Australia.

ABSTRACT
Background. We sought to determine and compare the prevalence of the Metabolic Syndrome (MS) in patients with acute myocardial infarction (AMI) utilizing the new International Diabetes Federation (IDF) definition with the older National Cholesterol Education Program (NCEP) definition. We also examined the clinical utility of MS in this context. Methods. A total of 107 consecutive patients with AMI were prospectively evaluated for MS. Fasting lipids obtained at admission and fasting glucose at discharge were used. A postdischarge folder audit verified rates of discharge coding and implementation of specific management strategies for MS. Results. Baseline patient characteristics included: mean age 59 +/- 13 years; males 80%; diabetes 19%; mean BMI 29.7 +/- 8.4 kg/m(2). MS prevalence was 54% by the IDF definition and 49% by the NCEP definition, with good agreement between definitions: kappa = 0.664, P < .001. Factors predictive of MS after multivariate analysis included: hypertension, fasting glucose, waist circumference, and serum HDL (all P < .05). Despite the high prevalence, MS was recognized at discharge in only 1 patient, and referral for exercise and/or weight-loss programs was undertaken in 5 patients. Conclusion. There is a high prevalence of MS utilizing contemporary definitions in patients with AMI: 54% by the IDF definition and 49% by NCEP criteria. Despite the high prevalence, MS was under-recognized and under-treated in this population.

No MeSH data available.


Related in: MedlinePlus