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Non-functional paraganglioma of the urinary bladder: a case report.

Xu DF, Chen M, Liu YS, Gao Y, Cui XG - J Med Case Rep (2010)

Bottom Line: A 55-year-old Chinese woman presenting with the sole complaint of lower abdominal pain for one month was admitted to our hospital.Ultrasound and computed tomography revealed a mass on the dome of the bladder measuring 4.0 x 3.0 cm.The tumor was completed removed by laparoscopic partial cystectomy.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Urology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China. charlessmmu@hotmail.com.

ABSTRACT

Introduction: Paragangliomas that originate from the urinary bladder are extremely rare. In most series, bladder paragangliomas often cause micturitional attacks. Treatment modalities include transurethral resection and cystectomy (partial or total). Prognosis of bladder paraganglioma is similar to that of adrenal pheochromocytoma.

Case presentation: A 55-year-old Chinese woman presenting with the sole complaint of lower abdominal pain for one month was admitted to our hospital. Ultrasound and computed tomography revealed a mass on the dome of the bladder measuring 4.0 x 3.0 cm. The tumor was completed removed by laparoscopic partial cystectomy. Histological examination of the tumor indicated paraganglioma of the urinary bladder. The clinical features, diagnosis, management and pathological findings of paraganglioma of the urinary bladder are discussed.

Conclusions: Bladder paraganglioma should be considered as a differential diagnosis to neoplasm in the urinary bladder, although there is no characteristic symptom. Laparoscopic partial cystectomy may be the first choice in treating paraganglioma of the urinary bladder, offering several advantages such as less invasion, rapid recovery and early discharge from the hospital.

No MeSH data available.


Related in: MedlinePlus

The tumor cells invade the muscular layer (hematoxylin and eosin ×100).
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Figure 3: The tumor cells invade the muscular layer (hematoxylin and eosin ×100).

Mentions: Pathological evaluation revealed paraganglioma to be the final diagnosis. On histopathologic examination, the tumor cells were arranged in a nested pattern (Figure 2). The tumor had invaded the muscular wall of the bladder (Figure 3). The tumor cells showed strong positive enhancement with synaptophysin (Figure 4) and neuron-specific enolase (NSE) (Figure 5), while immunostaining for chromogranin was negative.


Non-functional paraganglioma of the urinary bladder: a case report.

Xu DF, Chen M, Liu YS, Gao Y, Cui XG - J Med Case Rep (2010)

The tumor cells invade the muscular layer (hematoxylin and eosin ×100).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2913981&req=5

Figure 3: The tumor cells invade the muscular layer (hematoxylin and eosin ×100).
Mentions: Pathological evaluation revealed paraganglioma to be the final diagnosis. On histopathologic examination, the tumor cells were arranged in a nested pattern (Figure 2). The tumor had invaded the muscular wall of the bladder (Figure 3). The tumor cells showed strong positive enhancement with synaptophysin (Figure 4) and neuron-specific enolase (NSE) (Figure 5), while immunostaining for chromogranin was negative.

Bottom Line: A 55-year-old Chinese woman presenting with the sole complaint of lower abdominal pain for one month was admitted to our hospital.Ultrasound and computed tomography revealed a mass on the dome of the bladder measuring 4.0 x 3.0 cm.The tumor was completed removed by laparoscopic partial cystectomy.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Urology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China. charlessmmu@hotmail.com.

ABSTRACT

Introduction: Paragangliomas that originate from the urinary bladder are extremely rare. In most series, bladder paragangliomas often cause micturitional attacks. Treatment modalities include transurethral resection and cystectomy (partial or total). Prognosis of bladder paraganglioma is similar to that of adrenal pheochromocytoma.

Case presentation: A 55-year-old Chinese woman presenting with the sole complaint of lower abdominal pain for one month was admitted to our hospital. Ultrasound and computed tomography revealed a mass on the dome of the bladder measuring 4.0 x 3.0 cm. The tumor was completed removed by laparoscopic partial cystectomy. Histological examination of the tumor indicated paraganglioma of the urinary bladder. The clinical features, diagnosis, management and pathological findings of paraganglioma of the urinary bladder are discussed.

Conclusions: Bladder paraganglioma should be considered as a differential diagnosis to neoplasm in the urinary bladder, although there is no characteristic symptom. Laparoscopic partial cystectomy may be the first choice in treating paraganglioma of the urinary bladder, offering several advantages such as less invasion, rapid recovery and early discharge from the hospital.

No MeSH data available.


Related in: MedlinePlus