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Automated volumetric evaluation of stereoscopic disc photography.

Xu J, Ishikawa H, Wollstein G, Bilonick RA, Kagemann L, Craig JE, Mackey DA, Hewitt AW, Schuman JS - Opt Express (2010)

Bottom Line: Disc area, rim area, cup area, cup/disc area ratio, vertical cup/disc ratio, rim volume and cup volume were automatically computed by the algorithm.AP had better reproducibility for disc area and cup volume and worse reproducibility for cup/disc area ratio and vertical cup/disc ratio, when the measurements were compared to the MP, SLO and OCT methods.AP provides a useful technique for an objective quantitative assessment of 3D ONH structures.

View Article: PubMed Central - PubMed

Affiliation: UPMC Eye Center, Ophthalmology and Visual Science Research Center, Eye and Ear Institute, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

ABSTRACT

Purpose: To develop a fully automated algorithm (AP) to perform a volumetric measure of the optic disc using conventional stereoscopic optic nerve head (ONH) photographs, and to compare algorithm-produced parameters with manual photogrammetry (MP), scanning laser ophthalmoscope (SLO) and optical coherence tomography (OCT) measurements.

Methods: One hundred twenty-two stereoscopic optic disc photographs (61 subjects) were analyzed. Disc area, rim area, cup area, cup/disc area ratio, vertical cup/disc ratio, rim volume and cup volume were automatically computed by the algorithm. Latent variable measurement error models were used to assess measurement reproducibility for the four techniques.

Results: AP had better reproducibility for disc area and cup volume and worse reproducibility for cup/disc area ratio and vertical cup/disc ratio, when the measurements were compared to the MP, SLO and OCT methods.

Conclusion: AP provides a useful technique for an objective quantitative assessment of 3D ONH structures.

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Related in: MedlinePlus

Comparison between automatically photogrammetric algorithm and manual disc demarcation. (A) A successful example of disc demarcation. (B) An example of failure in disc demarcation due to prominent peripapillary atrophy.
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g005: Comparison between automatically photogrammetric algorithm and manual disc demarcation. (A) A successful example of disc demarcation. (B) An example of failure in disc demarcation due to prominent peripapillary atrophy.

Mentions: The mean age of the 61 participants in the study was 56.8 ± 9.6. Twenty-nine eyes (22 subjects) out of the 122 eyes (23.8%) were labeled as no-success by the automated quality assessment of AP. Examples of algorithm success and failure appear in Fig. 5Fig. 5


Automated volumetric evaluation of stereoscopic disc photography.

Xu J, Ishikawa H, Wollstein G, Bilonick RA, Kagemann L, Craig JE, Mackey DA, Hewitt AW, Schuman JS - Opt Express (2010)

Comparison between automatically photogrammetric algorithm and manual disc demarcation. (A) A successful example of disc demarcation. (B) An example of failure in disc demarcation due to prominent peripapillary atrophy.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2913866&req=5

g005: Comparison between automatically photogrammetric algorithm and manual disc demarcation. (A) A successful example of disc demarcation. (B) An example of failure in disc demarcation due to prominent peripapillary atrophy.
Mentions: The mean age of the 61 participants in the study was 56.8 ± 9.6. Twenty-nine eyes (22 subjects) out of the 122 eyes (23.8%) were labeled as no-success by the automated quality assessment of AP. Examples of algorithm success and failure appear in Fig. 5Fig. 5

Bottom Line: Disc area, rim area, cup area, cup/disc area ratio, vertical cup/disc ratio, rim volume and cup volume were automatically computed by the algorithm.AP had better reproducibility for disc area and cup volume and worse reproducibility for cup/disc area ratio and vertical cup/disc ratio, when the measurements were compared to the MP, SLO and OCT methods.AP provides a useful technique for an objective quantitative assessment of 3D ONH structures.

View Article: PubMed Central - PubMed

Affiliation: UPMC Eye Center, Ophthalmology and Visual Science Research Center, Eye and Ear Institute, Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

ABSTRACT

Purpose: To develop a fully automated algorithm (AP) to perform a volumetric measure of the optic disc using conventional stereoscopic optic nerve head (ONH) photographs, and to compare algorithm-produced parameters with manual photogrammetry (MP), scanning laser ophthalmoscope (SLO) and optical coherence tomography (OCT) measurements.

Methods: One hundred twenty-two stereoscopic optic disc photographs (61 subjects) were analyzed. Disc area, rim area, cup area, cup/disc area ratio, vertical cup/disc ratio, rim volume and cup volume were automatically computed by the algorithm. Latent variable measurement error models were used to assess measurement reproducibility for the four techniques.

Results: AP had better reproducibility for disc area and cup volume and worse reproducibility for cup/disc area ratio and vertical cup/disc ratio, when the measurements were compared to the MP, SLO and OCT methods.

Conclusion: AP provides a useful technique for an objective quantitative assessment of 3D ONH structures.

Show MeSH
Related in: MedlinePlus