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A road map for the global elimination of congenital syphilis.

Kamb ML, Newman LM, Riley PL, Mark J, Hawkes SJ, Malik T, Broutet N - Obstet Gynecol Int (2010)

Bottom Line: Congenital syphilis is the oldest recognized congenital infection, and continues to account for extensive global perinatal morbidity and mortality today.Serious adverse pregnancy outcomes caused by maternal syphilis infection are prevented with screening early in pregnancy and prompt treatment of women testing positive.Intramuscular penicillin, an inexpensive antibiotic on the essential medicine list of nations all over the world, effectively cures infection and prevents congenital syphilis.

View Article: PubMed Central - PubMed

Affiliation: Division of STD Prevention (DSTDP), International Activities Unit, U.S. Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd, NE, MS E-02, Atlanta, GA 30333, USA.

ABSTRACT
Congenital syphilis is the oldest recognized congenital infection, and continues to account for extensive global perinatal morbidity and mortality today. Serious adverse pregnancy outcomes caused by maternal syphilis infection are prevented with screening early in pregnancy and prompt treatment of women testing positive. Intramuscular penicillin, an inexpensive antibiotic on the essential medicine list of nations all over the world, effectively cures infection and prevents congenital syphilis. In fact, at a cost of $11-15 per disability adjusted life year (DALY) averted, maternal syphilis screening and treatment is among the most cost-effective public health interventions in existence. Yet implementation of this basic public health intervention is sporadic in countries with highest congenital syphilis burden. We discuss the global burden of this devastating disease, current progress and ongoing challenges for its elimination in countries with highest prevalence, and next steps in ensuring a world free of preventable perinatal deaths caused by syphilis.

No MeSH data available.


Related in: MedlinePlus

The four pillar strategy for elimination Congenital Syphilis.
© Copyright Policy - open-access
Related In: Results  -  Collection


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fig1: The four pillar strategy for elimination Congenital Syphilis.

Mentions: At a country level, WHO outlined a strategy consisting of four pillars with corresponding specific objectives of actions to be undertaken (Figure 1). The pillars are the following:


A road map for the global elimination of congenital syphilis.

Kamb ML, Newman LM, Riley PL, Mark J, Hawkes SJ, Malik T, Broutet N - Obstet Gynecol Int (2010)

The four pillar strategy for elimination Congenital Syphilis.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2913802&req=5

fig1: The four pillar strategy for elimination Congenital Syphilis.
Mentions: At a country level, WHO outlined a strategy consisting of four pillars with corresponding specific objectives of actions to be undertaken (Figure 1). The pillars are the following:

Bottom Line: Congenital syphilis is the oldest recognized congenital infection, and continues to account for extensive global perinatal morbidity and mortality today.Serious adverse pregnancy outcomes caused by maternal syphilis infection are prevented with screening early in pregnancy and prompt treatment of women testing positive.Intramuscular penicillin, an inexpensive antibiotic on the essential medicine list of nations all over the world, effectively cures infection and prevents congenital syphilis.

View Article: PubMed Central - PubMed

Affiliation: Division of STD Prevention (DSTDP), International Activities Unit, U.S. Centers for Disease Control and Prevention (CDC), 1600 Clifton Rd, NE, MS E-02, Atlanta, GA 30333, USA.

ABSTRACT
Congenital syphilis is the oldest recognized congenital infection, and continues to account for extensive global perinatal morbidity and mortality today. Serious adverse pregnancy outcomes caused by maternal syphilis infection are prevented with screening early in pregnancy and prompt treatment of women testing positive. Intramuscular penicillin, an inexpensive antibiotic on the essential medicine list of nations all over the world, effectively cures infection and prevents congenital syphilis. In fact, at a cost of $11-15 per disability adjusted life year (DALY) averted, maternal syphilis screening and treatment is among the most cost-effective public health interventions in existence. Yet implementation of this basic public health intervention is sporadic in countries with highest congenital syphilis burden. We discuss the global burden of this devastating disease, current progress and ongoing challenges for its elimination in countries with highest prevalence, and next steps in ensuring a world free of preventable perinatal deaths caused by syphilis.

No MeSH data available.


Related in: MedlinePlus