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Extramedullary plasmacytoma of the tonsil with nodal involvement.

Bazaadut S, Soodin D, Singh P, Khalafallah A, Withers S, Taylor S, Fernando R - Int J Otolaryngol (2010)

Bottom Line: A 58-year-old Caucasian male presented with a solitary 3 cm x 3 cm jugulodigastric lymph node and was found to have an ipsilateral tonsillar swelling.The involved tonsil and lymph node were surgically resected after two inconclusive fine-needle aspirates, and plasmacytoma was confirmed histologically and by immunocytochemistry.We also highlight the challenges of diagnosis when fine-needle aspiration is inconclusive and the need for careful planning before surgery.

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology, Launceston General Hospital, Tasmania, Australia.

ABSTRACT
We present a rare case of extramedullary plasmacytoma of the palatine tonsil with cervical lymph node involvement treated by surgical resection. A 58-year-old Caucasian male presented with a solitary 3 cm x 3 cm jugulodigastric lymph node and was found to have an ipsilateral tonsillar swelling. The involved tonsil and lymph node were surgically resected after two inconclusive fine-needle aspirates, and plasmacytoma was confirmed histologically and by immunocytochemistry. Adjuvant radiotherapy was not indicated as adequate resection was achieved at surgery. We also highlight the challenges of diagnosis when fine-needle aspiration is inconclusive and the need for careful planning before surgery.

No MeSH data available.


Related in: MedlinePlus

Tonsillar tissue with intact surface squamous epithelium (arrow) and underlying diffuse infiltrate of neoplastic plasma cells (H & E stain, x10).
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fig3: Tonsillar tissue with intact surface squamous epithelium (arrow) and underlying diffuse infiltrate of neoplastic plasma cells (H & E stain, x10).

Mentions: Histologies of both the tonsillar mass and the lymph node were similar, showing effacement of normal architecture and extensive infiltration with diffuse sheets of neoplastic cells possessing plasmacytoid morphology with eccentric nuclei exhibiting “clock-faced” nuclear chromatin pattern that typically represent plasma cells. Binucleate and multinucleate forms were also present (Figure 2). The tonsillar lesion was fairly circumscribed and the epithelium was not infiltrated (Figure 3).


Extramedullary plasmacytoma of the tonsil with nodal involvement.

Bazaadut S, Soodin D, Singh P, Khalafallah A, Withers S, Taylor S, Fernando R - Int J Otolaryngol (2010)

Tonsillar tissue with intact surface squamous epithelium (arrow) and underlying diffuse infiltrate of neoplastic plasma cells (H & E stain, x10).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2913787&req=5

fig3: Tonsillar tissue with intact surface squamous epithelium (arrow) and underlying diffuse infiltrate of neoplastic plasma cells (H & E stain, x10).
Mentions: Histologies of both the tonsillar mass and the lymph node were similar, showing effacement of normal architecture and extensive infiltration with diffuse sheets of neoplastic cells possessing plasmacytoid morphology with eccentric nuclei exhibiting “clock-faced” nuclear chromatin pattern that typically represent plasma cells. Binucleate and multinucleate forms were also present (Figure 2). The tonsillar lesion was fairly circumscribed and the epithelium was not infiltrated (Figure 3).

Bottom Line: A 58-year-old Caucasian male presented with a solitary 3 cm x 3 cm jugulodigastric lymph node and was found to have an ipsilateral tonsillar swelling.The involved tonsil and lymph node were surgically resected after two inconclusive fine-needle aspirates, and plasmacytoma was confirmed histologically and by immunocytochemistry.We also highlight the challenges of diagnosis when fine-needle aspiration is inconclusive and the need for careful planning before surgery.

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology, Launceston General Hospital, Tasmania, Australia.

ABSTRACT
We present a rare case of extramedullary plasmacytoma of the palatine tonsil with cervical lymph node involvement treated by surgical resection. A 58-year-old Caucasian male presented with a solitary 3 cm x 3 cm jugulodigastric lymph node and was found to have an ipsilateral tonsillar swelling. The involved tonsil and lymph node were surgically resected after two inconclusive fine-needle aspirates, and plasmacytoma was confirmed histologically and by immunocytochemistry. Adjuvant radiotherapy was not indicated as adequate resection was achieved at surgery. We also highlight the challenges of diagnosis when fine-needle aspiration is inconclusive and the need for careful planning before surgery.

No MeSH data available.


Related in: MedlinePlus