6-hydroxydopamine-mediated release of norepinephrine increases faecal excretion of Salmonella enterica serovar Typhimurium in pigs.
Bottom Line: The stress-related catecholamine norepinephrine (NE) has been reported to activate growth and virulence factor expression in Salmonella; however the extent to which NE contributes to stress-associated salmonellosis is unclear.Salmonella has been proposed to sense and respond to NE via a homologue of the adrenergic sensor kinase QseC.Our data support the notion that stress-related catecholamines modulate the interaction of enteric bacterial pathogens with their hosts.
Affiliation: Enteric Bacterial Pathogens Laboratory, Institute for Animal Health, Compton, Berkshire RG20 7NN, United Kingdom.Show MeSH
Related in: MedlinePlus
Affiliation: Enteric Bacterial Pathogens Laboratory, Institute for Animal Health, Compton, Berkshire RG20 7NN, United Kingdom.