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The relationship between optical coherence tomography and scanning laser polarimetry measurements in glaucoma.

Chung YS, Sohn YH - Korean J Ophthalmol (2006)

Bottom Line: First, parameters of the Stratus OCT (average thickness, superior/inferior average) and GDx VCC (TSNIT average, nerve fiber indicator (NFI), superior/inferior average) were correlated using the Pearson's correlation coefficient (r).The following parameters were found to be significantly correlated (P < 0.005).TSNIT average/average thickness (r = 0.673), NFI/average thickness (r = -0.742), superior average (r = 0.841), and inferior average (r = 0.736).

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Hallym University College of Medicine, Anyang, Korea.

ABSTRACT

Purpose: To investigate the relationship between optical coherence tomography (OCT) and scanning laser polarimetry (SLP) in measuring peripapillary retinal nerve fiber layer (RNFL) thickness in glaucomatous eyes.

Methods: Fifty glaucomatous eyes were evaluated in this study. Evaluations were analyzed two ways. First, parameters of the Stratus OCT (average thickness, superior/inferior average) and GDx VCC (TSNIT average, nerve fiber indicator (NFI), superior/inferior average) were correlated using the Pearson's correlation coefficient (r). Secondly, comparison (r) of these parameters was completed using the mean deviation (MD) of visual field defect.

Results: The following parameters were found to be significantly correlated (P < 0.005). TSNIT average/average thickness (r = 0.673), NFI/average thickness (r = -0.742), superior average (r = 0.841), and inferior average (r = 0.736). In the correlation analysis using the severity of visual field defect, all these parameters had statistically meaningful correlations (P < 0.005).

Conclusions: GDx VCC and Stratus OCT are highly correlated in glaucomatous eyes. Therefore, peripapillary RNFL thickness measured by Stratus OCT and GDx VCC may be equally helpful in the diagnosis of glaucoma.

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Scatterplot of TSNIT average versus average thickness.
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Figure 1: Scatterplot of TSNIT average versus average thickness.

Mentions: The relationships between GDx VCC and Stratus OCT parameters are graphically represented in Figs. 1, 2, 3, and 4. Statistically significant correlations were observed in each parameter (P<0.005). Pearson coefficients were as follows: 0.673 for TSNIT average/average thickness (Fig. 1), -0.742 for NFI/average thickness (Fig. 2), 0.841 for superior average (Fig. 3), and 0.736 for inferior average (Fig. 4). All parameters had positive correlations except for the NFI because NFI has a higher positive value in glaucoma.


The relationship between optical coherence tomography and scanning laser polarimetry measurements in glaucoma.

Chung YS, Sohn YH - Korean J Ophthalmol (2006)

Scatterplot of TSNIT average versus average thickness.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2908856&req=5

Figure 1: Scatterplot of TSNIT average versus average thickness.
Mentions: The relationships between GDx VCC and Stratus OCT parameters are graphically represented in Figs. 1, 2, 3, and 4. Statistically significant correlations were observed in each parameter (P<0.005). Pearson coefficients were as follows: 0.673 for TSNIT average/average thickness (Fig. 1), -0.742 for NFI/average thickness (Fig. 2), 0.841 for superior average (Fig. 3), and 0.736 for inferior average (Fig. 4). All parameters had positive correlations except for the NFI because NFI has a higher positive value in glaucoma.

Bottom Line: First, parameters of the Stratus OCT (average thickness, superior/inferior average) and GDx VCC (TSNIT average, nerve fiber indicator (NFI), superior/inferior average) were correlated using the Pearson's correlation coefficient (r).The following parameters were found to be significantly correlated (P < 0.005).TSNIT average/average thickness (r = 0.673), NFI/average thickness (r = -0.742), superior average (r = 0.841), and inferior average (r = 0.736).

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Hallym University College of Medicine, Anyang, Korea.

ABSTRACT

Purpose: To investigate the relationship between optical coherence tomography (OCT) and scanning laser polarimetry (SLP) in measuring peripapillary retinal nerve fiber layer (RNFL) thickness in glaucomatous eyes.

Methods: Fifty glaucomatous eyes were evaluated in this study. Evaluations were analyzed two ways. First, parameters of the Stratus OCT (average thickness, superior/inferior average) and GDx VCC (TSNIT average, nerve fiber indicator (NFI), superior/inferior average) were correlated using the Pearson's correlation coefficient (r). Secondly, comparison (r) of these parameters was completed using the mean deviation (MD) of visual field defect.

Results: The following parameters were found to be significantly correlated (P < 0.005). TSNIT average/average thickness (r = 0.673), NFI/average thickness (r = -0.742), superior average (r = 0.841), and inferior average (r = 0.736). In the correlation analysis using the severity of visual field defect, all these parameters had statistically meaningful correlations (P < 0.005).

Conclusions: GDx VCC and Stratus OCT are highly correlated in glaucomatous eyes. Therefore, peripapillary RNFL thickness measured by Stratus OCT and GDx VCC may be equally helpful in the diagnosis of glaucoma.

Show MeSH
Related in: MedlinePlus