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Trends in deceased organ donation and utilization in Korea: 2000-2009.

Min SI, Kim SY, Park YJ, Min SK, Kim YS, Ahn C, Kim SJ, Ha J - J. Korean Med. Sci. (2010)

Bottom Line: Therefore, the percentage of standard criteria donors (SCD) has been declining significantly, from 94% in 2000 to 79.2% in 2009.This decline may be attributable to increases in the number and percentage of extended criteria donors (ECD) and donors after cardiac death (DCD), since the OTPD was 2.25 for DCD, 2.5 for ECD, and 3.09 for SCD in 2009.In summary, the makeup of donors has changed significantly.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.

ABSTRACT
Continuous efforts have been made by the organ donation and transplantation community in Korea to increase organ donation by the deceased. The authors detailed trends of organ donation and utilization over the past 10 yr using data provided by the KONOS. The yearly number of deceased donors has grown gradually since 2003. The number and percentage of old donors (> or = 50 yr) and donors dying from intracranial hemorrhage has increased continuously. Therefore, the percentage of standard criteria donors (SCD) has been declining significantly, from 94% in 2000 to 79.2% in 2009. The number of organs transplanted per donor (OTPD) has also declined slightly since 2007, from 3.28 in 2007 to 2.95 in 2009. This decline may be attributable to increases in the number and percentage of extended criteria donors (ECD) and donors after cardiac death (DCD), since the OTPD was 2.25 for DCD, 2.5 for ECD, and 3.09 for SCD in 2009. In summary, the makeup of donors has changed significantly. There is an urgent need for establishment of an institutional framework including an independent organ procurement organization and for improvement for the National Transplant Act to increase deceased donor pool and to optimize management of ECD and DCD.

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Related in: MedlinePlus

Organs transplanted per donor (OTPD) by donor type and organs transplanted. (A) Kidney, (B) Liver, (C) Pancreas and (D) Heart.
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Figure 5: Organs transplanted per donor (OTPD) by donor type and organs transplanted. (A) Kidney, (B) Liver, (C) Pancreas and (D) Heart.

Mentions: Changes in the numbers of specific organs per donor type are illustrated in Fig. 5. The number of kidneys transplanted per SCD has not changed dramatically over the past 10 yr (2.0 in 2000 and 1.95 in 2009). However, with increases in ECD, the number of kidneys transplanted per ECD has dropped, from 2.0 to 1.85 over that period. DCD did not affect the numbers of transplanted kidneys. As the ECD numbers increase and begin to account for a larger fraction of the percentage of national deceased donors, its impact on OTPD increases. Although the current definition of ECD is specific for the kidney and many groups have attempted to define the ECD for other organs (10), their guidelines have yet to be generally accepted. Considering this lack of definition for 'expanded criteria' livers, pancreata, and hearts, the authors compared the numbers of these organs transplanted per donor providing organs after brain death (DBD) to the numbers of donors providing organs after cardiac death (DCD). The numbers of other solid organs (livers, pancreata, and hearts) transplanted per DBD have not changed markedly. The utilization of livers has increased slightly, with the number of livers transplanted per DBD increasing from 0.62 in 2000 to 0.8 in 2009. Pancreas and heart utilization from DBD has remained relatively stable, at approximately 0.1 to 0.2 pancreata or hearts transplanted per DBD donor. However, that number per DCD donor is relatively low. The number of livers transplanted per DCD donor was only 0.25 in 2009. Neither pancreata nor hearts have been procured and transplanted from DCD.


Trends in deceased organ donation and utilization in Korea: 2000-2009.

Min SI, Kim SY, Park YJ, Min SK, Kim YS, Ahn C, Kim SJ, Ha J - J. Korean Med. Sci. (2010)

Organs transplanted per donor (OTPD) by donor type and organs transplanted. (A) Kidney, (B) Liver, (C) Pancreas and (D) Heart.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2908778&req=5

Figure 5: Organs transplanted per donor (OTPD) by donor type and organs transplanted. (A) Kidney, (B) Liver, (C) Pancreas and (D) Heart.
Mentions: Changes in the numbers of specific organs per donor type are illustrated in Fig. 5. The number of kidneys transplanted per SCD has not changed dramatically over the past 10 yr (2.0 in 2000 and 1.95 in 2009). However, with increases in ECD, the number of kidneys transplanted per ECD has dropped, from 2.0 to 1.85 over that period. DCD did not affect the numbers of transplanted kidneys. As the ECD numbers increase and begin to account for a larger fraction of the percentage of national deceased donors, its impact on OTPD increases. Although the current definition of ECD is specific for the kidney and many groups have attempted to define the ECD for other organs (10), their guidelines have yet to be generally accepted. Considering this lack of definition for 'expanded criteria' livers, pancreata, and hearts, the authors compared the numbers of these organs transplanted per donor providing organs after brain death (DBD) to the numbers of donors providing organs after cardiac death (DCD). The numbers of other solid organs (livers, pancreata, and hearts) transplanted per DBD have not changed markedly. The utilization of livers has increased slightly, with the number of livers transplanted per DBD increasing from 0.62 in 2000 to 0.8 in 2009. Pancreas and heart utilization from DBD has remained relatively stable, at approximately 0.1 to 0.2 pancreata or hearts transplanted per DBD donor. However, that number per DCD donor is relatively low. The number of livers transplanted per DCD donor was only 0.25 in 2009. Neither pancreata nor hearts have been procured and transplanted from DCD.

Bottom Line: Therefore, the percentage of standard criteria donors (SCD) has been declining significantly, from 94% in 2000 to 79.2% in 2009.This decline may be attributable to increases in the number and percentage of extended criteria donors (ECD) and donors after cardiac death (DCD), since the OTPD was 2.25 for DCD, 2.5 for ECD, and 3.09 for SCD in 2009.In summary, the makeup of donors has changed significantly.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.

ABSTRACT
Continuous efforts have been made by the organ donation and transplantation community in Korea to increase organ donation by the deceased. The authors detailed trends of organ donation and utilization over the past 10 yr using data provided by the KONOS. The yearly number of deceased donors has grown gradually since 2003. The number and percentage of old donors (> or = 50 yr) and donors dying from intracranial hemorrhage has increased continuously. Therefore, the percentage of standard criteria donors (SCD) has been declining significantly, from 94% in 2000 to 79.2% in 2009. The number of organs transplanted per donor (OTPD) has also declined slightly since 2007, from 3.28 in 2007 to 2.95 in 2009. This decline may be attributable to increases in the number and percentage of extended criteria donors (ECD) and donors after cardiac death (DCD), since the OTPD was 2.25 for DCD, 2.5 for ECD, and 3.09 for SCD in 2009. In summary, the makeup of donors has changed significantly. There is an urgent need for establishment of an institutional framework including an independent organ procurement organization and for improvement for the National Transplant Act to increase deceased donor pool and to optimize management of ECD and DCD.

Show MeSH
Related in: MedlinePlus