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Developmental toxicity of endocrine disrupters bisphenol A and vinclozolin in a terrestrial isopod.

Lemos MF, van Gestel CA, Soares AM - Arch. Environ. Contam. Toxicol. (2010)

Bottom Line: Both chemicals elicited developmental toxicity to P. scaber by causing overall decreased growth.Although the LC50 values for juvenile and adult survival were fairly similar, juvenile woodlice showed an increased chronic sensitivity to both chemicals, and female woodlice were most the sensitive to BPA.We recommend the use of adults, juveniles, female, and male woodlice, as well as a large range of toxicant concentrations, to provide valuable information regarding differential dose responses, effects, and threshold values for EDCs.

View Article: PubMed Central - PubMed

Affiliation: CESAM and Department of Biology, University of Aveiro, 3810-193, Aveiro, Portugal. mlemos@ua.pt

ABSTRACT
Studies of the effects of endocrine-disrupting compounds (EDCs) on invertebrates are still largely underrepresented. This work aims to fill this gap by assessing the effects of bisphenol A (BPA) and vinclozolin (Vz) on the terrestrial isopod Porcellio scaber (common rough woodlouse). Male adult and sexually undifferentiated juvenile woodlice were exposed to the toxicants. Effects on molting regime and growth were investigated independently for males and female woodlice after sexual differentiation. Both chemicals elicited developmental toxicity to P. scaber by causing overall decreased growth. Nevertheless, BPA induced molting, whereas Vz delayed it. Although the LC50 values for juvenile and adult survival were fairly similar, juvenile woodlice showed an increased chronic sensitivity to both chemicals, and female woodlice were most the sensitive to BPA. We recommend the use of adults, juveniles, female, and male woodlice, as well as a large range of toxicant concentrations, to provide valuable information regarding differential dose responses, effects, and threshold values for EDCs.

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Growth of adult male P. scaber after 10 week exposure to soil treated with a Vz and b BPA. Black bars represent size gain (final CW/initial CW), and grey bars represent mass gain (final weight/initial weight). * Significant difference from the control at p ≤ 0.05 (ANOVA, Dunnett’s test)
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Fig1: Growth of adult male P. scaber after 10 week exposure to soil treated with a Vz and b BPA. Black bars represent size gain (final CW/initial CW), and grey bars represent mass gain (final weight/initial weight). * Significant difference from the control at p ≤ 0.05 (ANOVA, Dunnett’s test)

Mentions: After 10 weeks, control woodlice gained 83% in mass and showed an increase of 24% in size (Fig. 1a). The woodlice exposed to 10, 30, and 100 mg a.i. Vz/kg soil tended to increase in size and mass compared with controls, whereas a decreased in these growth parameters was visible at the highest concentration tested. The increase in the CW was lower and significantly different from controls exposed to 300 mg a.i. Vz/kg soil (ANOVA, Dunnett’s test, F4.29 = 2.941, p = 0.037).Fig. 1


Developmental toxicity of endocrine disrupters bisphenol A and vinclozolin in a terrestrial isopod.

Lemos MF, van Gestel CA, Soares AM - Arch. Environ. Contam. Toxicol. (2010)

Growth of adult male P. scaber after 10 week exposure to soil treated with a Vz and b BPA. Black bars represent size gain (final CW/initial CW), and grey bars represent mass gain (final weight/initial weight). * Significant difference from the control at p ≤ 0.05 (ANOVA, Dunnett’s test)
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2908429&req=5

Fig1: Growth of adult male P. scaber after 10 week exposure to soil treated with a Vz and b BPA. Black bars represent size gain (final CW/initial CW), and grey bars represent mass gain (final weight/initial weight). * Significant difference from the control at p ≤ 0.05 (ANOVA, Dunnett’s test)
Mentions: After 10 weeks, control woodlice gained 83% in mass and showed an increase of 24% in size (Fig. 1a). The woodlice exposed to 10, 30, and 100 mg a.i. Vz/kg soil tended to increase in size and mass compared with controls, whereas a decreased in these growth parameters was visible at the highest concentration tested. The increase in the CW was lower and significantly different from controls exposed to 300 mg a.i. Vz/kg soil (ANOVA, Dunnett’s test, F4.29 = 2.941, p = 0.037).Fig. 1

Bottom Line: Both chemicals elicited developmental toxicity to P. scaber by causing overall decreased growth.Although the LC50 values for juvenile and adult survival were fairly similar, juvenile woodlice showed an increased chronic sensitivity to both chemicals, and female woodlice were most the sensitive to BPA.We recommend the use of adults, juveniles, female, and male woodlice, as well as a large range of toxicant concentrations, to provide valuable information regarding differential dose responses, effects, and threshold values for EDCs.

View Article: PubMed Central - PubMed

Affiliation: CESAM and Department of Biology, University of Aveiro, 3810-193, Aveiro, Portugal. mlemos@ua.pt

ABSTRACT
Studies of the effects of endocrine-disrupting compounds (EDCs) on invertebrates are still largely underrepresented. This work aims to fill this gap by assessing the effects of bisphenol A (BPA) and vinclozolin (Vz) on the terrestrial isopod Porcellio scaber (common rough woodlouse). Male adult and sexually undifferentiated juvenile woodlice were exposed to the toxicants. Effects on molting regime and growth were investigated independently for males and female woodlice after sexual differentiation. Both chemicals elicited developmental toxicity to P. scaber by causing overall decreased growth. Nevertheless, BPA induced molting, whereas Vz delayed it. Although the LC50 values for juvenile and adult survival were fairly similar, juvenile woodlice showed an increased chronic sensitivity to both chemicals, and female woodlice were most the sensitive to BPA. We recommend the use of adults, juveniles, female, and male woodlice, as well as a large range of toxicant concentrations, to provide valuable information regarding differential dose responses, effects, and threshold values for EDCs.

Show MeSH
Related in: MedlinePlus