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Does lower birth order amplify the association between high socioeconomic status and central adiposity in young adult Filipino males?

Dahly DL, Adair LS - Int J Obes (Lond) (2010)

Bottom Line: Lower birth order was associated with higher waist circumference and increased odds of high waist circumference, even after adjustment for socioeconomic status in young adulthood and maternal characteristics that could impact later offspring adiposity.Furthermore, the positive association between socioeconomic status and central adiposity was amplified in individuals characterized by lower birth order.This research has failed to reject the mismatch hypothesis, which posits that maternal constraint of fetal growth acts to program developing physiology in a manner that increases susceptibility to the obesogenic effects of modern environments.

View Article: PubMed Central - PubMed

Affiliation: Centre for Epidemiology and Biostatistics, University of Leeds, Leeds, UK. d.l.dahly@leeds.ac.uk

ABSTRACT

Objectives: To test the hypothesis that lower birth order amplifies the positive association between socioeconomic status and central adiposity in young adult males from a lower income, developing country context.

Design: The Cebu Longitudinal Health and Nutrition Survey is an ongoing community-based, observational study of a 1-year birth cohort (1983).

Subjects: 970 young adult males, mean age 21.5 years (2005).

Measurements: Central adiposity measured by waist circumference; birth order; perinatal maternal characteristics including height, arm fat area, age and smoking behavior; socioeconomic status at birth and in young adulthood.

Results: Lower birth order was associated with higher waist circumference and increased odds of high waist circumference, even after adjustment for socioeconomic status in young adulthood and maternal characteristics that could impact later offspring adiposity. Furthermore, the positive association between socioeconomic status and central adiposity was amplified in individuals characterized by lower birth order.

Conclusions: This research has failed to reject the mismatch hypothesis, which posits that maternal constraint of fetal growth acts to program developing physiology in a manner that increases susceptibility to the obesogenic effects of modern environments.

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Related in: MedlinePlus

Mean body mass index growth curves (with 95% confidence intervals) for groups of males defined by firstborn status and socioeconomic status at birth.
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Figure 4: Mean body mass index growth curves (with 95% confidence intervals) for groups of males defined by firstborn status and socioeconomic status at birth.

Mentions: Mean BMI growth curves of four groups based on firstborn status and SES are displayed in figure 4. The high SES, firstborn group was characterized by low BMI at birth and rapid early postnatal gains in BMI. They had the largest mean BMI by six months, though at two years they were not distinguishable from the other high SES group. However, they had the largest increase in BMI across childhood and adolescence, resulting in the highest mean BMI in young adulthood. While BMI growth curves among high SES individuals were differentiated by firstborn status, there was no apparent impact of firstborn among lower SES individuals.


Does lower birth order amplify the association between high socioeconomic status and central adiposity in young adult Filipino males?

Dahly DL, Adair LS - Int J Obes (Lond) (2010)

Mean body mass index growth curves (with 95% confidence intervals) for groups of males defined by firstborn status and socioeconomic status at birth.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2908417&req=5

Figure 4: Mean body mass index growth curves (with 95% confidence intervals) for groups of males defined by firstborn status and socioeconomic status at birth.
Mentions: Mean BMI growth curves of four groups based on firstborn status and SES are displayed in figure 4. The high SES, firstborn group was characterized by low BMI at birth and rapid early postnatal gains in BMI. They had the largest mean BMI by six months, though at two years they were not distinguishable from the other high SES group. However, they had the largest increase in BMI across childhood and adolescence, resulting in the highest mean BMI in young adulthood. While BMI growth curves among high SES individuals were differentiated by firstborn status, there was no apparent impact of firstborn among lower SES individuals.

Bottom Line: Lower birth order was associated with higher waist circumference and increased odds of high waist circumference, even after adjustment for socioeconomic status in young adulthood and maternal characteristics that could impact later offspring adiposity.Furthermore, the positive association between socioeconomic status and central adiposity was amplified in individuals characterized by lower birth order.This research has failed to reject the mismatch hypothesis, which posits that maternal constraint of fetal growth acts to program developing physiology in a manner that increases susceptibility to the obesogenic effects of modern environments.

View Article: PubMed Central - PubMed

Affiliation: Centre for Epidemiology and Biostatistics, University of Leeds, Leeds, UK. d.l.dahly@leeds.ac.uk

ABSTRACT

Objectives: To test the hypothesis that lower birth order amplifies the positive association between socioeconomic status and central adiposity in young adult males from a lower income, developing country context.

Design: The Cebu Longitudinal Health and Nutrition Survey is an ongoing community-based, observational study of a 1-year birth cohort (1983).

Subjects: 970 young adult males, mean age 21.5 years (2005).

Measurements: Central adiposity measured by waist circumference; birth order; perinatal maternal characteristics including height, arm fat area, age and smoking behavior; socioeconomic status at birth and in young adulthood.

Results: Lower birth order was associated with higher waist circumference and increased odds of high waist circumference, even after adjustment for socioeconomic status in young adulthood and maternal characteristics that could impact later offspring adiposity. Furthermore, the positive association between socioeconomic status and central adiposity was amplified in individuals characterized by lower birth order.

Conclusions: This research has failed to reject the mismatch hypothesis, which posits that maternal constraint of fetal growth acts to program developing physiology in a manner that increases susceptibility to the obesogenic effects of modern environments.

Show MeSH
Related in: MedlinePlus