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Cutaneous lesions of the nose.

Sand M, Sand D, Thrandorf C, Paech V, Altmeyer P, Bechara FG - Head Face Med (2010)

Bottom Line: Skin diseases on the nose are seen in a variety of medical disciplines.Dermatologists, otorhinolaryngologists, general practitioners and general plastic and dermatologic surgeons are regularly consulted regarding cutaneous lesions on the nose.This article is the second part of a review series dealing with cutaneous lesions on the head and face, which are frequently seen in daily practice by a dermatologic surgeon.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Dermatology and Allergology, Dermatologic Surgery Unit, Ruhr-University Bochum, Gudrunstr 56, 44791 Bochum, Germany. michael.sand@ruhr-uni-bochum.de

ABSTRACT
Skin diseases on the nose are seen in a variety of medical disciplines. Dermatologists, otorhinolaryngologists, general practitioners and general plastic and dermatologic surgeons are regularly consulted regarding cutaneous lesions on the nose. This article is the second part of a review series dealing with cutaneous lesions on the head and face, which are frequently seen in daily practice by a dermatologic surgeon. In this review, we focus on those skin diseases on the nose where surgery or laser therapy is considered a possible treatment option or that can be surgically evaluated.

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Cutaneous lesions of sarcoidosis (lupus pernio). Red-to-purple indurated plaques and nodules affecting the nose and cheeks.
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Figure 11: Cutaneous lesions of sarcoidosis (lupus pernio). Red-to-purple indurated plaques and nodules affecting the nose and cheeks.

Mentions: Sarcoidosis is a multisystem granulomatous inflammatory disease that can affect any organ. Cutaneous sarcoidosis is characterized by non-caseating granulomatas that consist of mononuclear phagocytes, epithelioid macrophages and multinucleate giant cells [103]. The macronodular type involving the nose and cheek is called lupus pernio and was first described by Besnier in 1889 [104]. The etiology of this disease is still unknown. Clinically, dark red, purple or violaceous plaques and nodules can be seen [Fig. 11]. The serum concentration of angiotensin-converting enzyme (ACE) is increased, and measurements have been used as an index of disease activity. Aside from topical and intra-lesional steroids, multiple forms of internal therapy (immunosuppressants such as steroids, interleukin-2 inhibitors or anti-tumor necrosis factor alpha treatment) have been described [105]. Pulsed dye or CO2 laser ablation is available for the debulking of granulomatous lesions; however, there are no evidence-based recommendations because of the limited number of patients treated [105].


Cutaneous lesions of the nose.

Sand M, Sand D, Thrandorf C, Paech V, Altmeyer P, Bechara FG - Head Face Med (2010)

Cutaneous lesions of sarcoidosis (lupus pernio). Red-to-purple indurated plaques and nodules affecting the nose and cheeks.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2903548&req=5

Figure 11: Cutaneous lesions of sarcoidosis (lupus pernio). Red-to-purple indurated plaques and nodules affecting the nose and cheeks.
Mentions: Sarcoidosis is a multisystem granulomatous inflammatory disease that can affect any organ. Cutaneous sarcoidosis is characterized by non-caseating granulomatas that consist of mononuclear phagocytes, epithelioid macrophages and multinucleate giant cells [103]. The macronodular type involving the nose and cheek is called lupus pernio and was first described by Besnier in 1889 [104]. The etiology of this disease is still unknown. Clinically, dark red, purple or violaceous plaques and nodules can be seen [Fig. 11]. The serum concentration of angiotensin-converting enzyme (ACE) is increased, and measurements have been used as an index of disease activity. Aside from topical and intra-lesional steroids, multiple forms of internal therapy (immunosuppressants such as steroids, interleukin-2 inhibitors or anti-tumor necrosis factor alpha treatment) have been described [105]. Pulsed dye or CO2 laser ablation is available for the debulking of granulomatous lesions; however, there are no evidence-based recommendations because of the limited number of patients treated [105].

Bottom Line: Skin diseases on the nose are seen in a variety of medical disciplines.Dermatologists, otorhinolaryngologists, general practitioners and general plastic and dermatologic surgeons are regularly consulted regarding cutaneous lesions on the nose.This article is the second part of a review series dealing with cutaneous lesions on the head and face, which are frequently seen in daily practice by a dermatologic surgeon.

View Article: PubMed Central - HTML - PubMed

Affiliation: Department of Dermatology and Allergology, Dermatologic Surgery Unit, Ruhr-University Bochum, Gudrunstr 56, 44791 Bochum, Germany. michael.sand@ruhr-uni-bochum.de

ABSTRACT
Skin diseases on the nose are seen in a variety of medical disciplines. Dermatologists, otorhinolaryngologists, general practitioners and general plastic and dermatologic surgeons are regularly consulted regarding cutaneous lesions on the nose. This article is the second part of a review series dealing with cutaneous lesions on the head and face, which are frequently seen in daily practice by a dermatologic surgeon. In this review, we focus on those skin diseases on the nose where surgery or laser therapy is considered a possible treatment option or that can be surgically evaluated.

Show MeSH
Related in: MedlinePlus