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Survival of massive allografts in segmental oncological bone defect reconstructions.

Bullens PH, Minderhoud NM, de Waal Malefijt MC, Veth RP, Buma P, Schreuder HW - Int Orthop (2008)

Bottom Line: The average follow-up for this group was five years and three months.We found a low union rate of 25%.We found a five-year allograft survival of 80.8% which is comparable with other studies.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedic Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

ABSTRACT
Reconstructions of large segmental bone defects after resection of bone tumours with massive structural allografts have a high number of reported complications including fracture, infection and non-union. Our goal is to report the survival and complications of massive allografts in our patients. A total of 32 patients were evaluated for fracture, infection, non-union rate and survival of their massive allograft reconstructions. The average follow-up for this group was five years and three months. The total fracture rate was 13% with a total infection rate of 16%. We found a low union rate of 25%. The total survival of the allografts was 80.8% (+/- 18.7%) after five years. We found a five-year allograft survival of 80.8% which is comparable with other studies.

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Non-union and failure of fixation in an intercalary allograft reconstruction
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Fig3: Non-union and failure of fixation in an intercalary allograft reconstruction

Mentions: One patient had an intercalary allograft removed due to a deep infection (at 159 months). After débridement and removal of the graft a mega-prosthesis was implanted. Two patients with an endoprosthesis had a deep infection leading to a chronic fistula which was not treated. In the intercalary graft group two plate fractures were observed leading to a stable fibrous non-union in one and a revision in the other (Fig. 3). All three patients with an arthrodesis nail suffered from complications. One had a deep infection which was débrided and treated with local antibiotics and two developed a fracture of the arthrodesis nail which was treated with a revision of the nail.Fig. 3


Survival of massive allografts in segmental oncological bone defect reconstructions.

Bullens PH, Minderhoud NM, de Waal Malefijt MC, Veth RP, Buma P, Schreuder HW - Int Orthop (2008)

Non-union and failure of fixation in an intercalary allograft reconstruction
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2903090&req=5

Fig3: Non-union and failure of fixation in an intercalary allograft reconstruction
Mentions: One patient had an intercalary allograft removed due to a deep infection (at 159 months). After débridement and removal of the graft a mega-prosthesis was implanted. Two patients with an endoprosthesis had a deep infection leading to a chronic fistula which was not treated. In the intercalary graft group two plate fractures were observed leading to a stable fibrous non-union in one and a revision in the other (Fig. 3). All three patients with an arthrodesis nail suffered from complications. One had a deep infection which was débrided and treated with local antibiotics and two developed a fracture of the arthrodesis nail which was treated with a revision of the nail.Fig. 3

Bottom Line: The average follow-up for this group was five years and three months.We found a low union rate of 25%.We found a five-year allograft survival of 80.8% which is comparable with other studies.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedic Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

ABSTRACT
Reconstructions of large segmental bone defects after resection of bone tumours with massive structural allografts have a high number of reported complications including fracture, infection and non-union. Our goal is to report the survival and complications of massive allografts in our patients. A total of 32 patients were evaluated for fracture, infection, non-union rate and survival of their massive allograft reconstructions. The average follow-up for this group was five years and three months. The total fracture rate was 13% with a total infection rate of 16%. We found a low union rate of 25%. The total survival of the allografts was 80.8% (+/- 18.7%) after five years. We found a five-year allograft survival of 80.8% which is comparable with other studies.

Show MeSH
Related in: MedlinePlus