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Survival of massive allografts in segmental oncological bone defect reconstructions.

Bullens PH, Minderhoud NM, de Waal Malefijt MC, Veth RP, Buma P, Schreuder HW - Int Orthop (2008)

Bottom Line: The average follow-up for this group was five years and three months.We found a low union rate of 25%.We found a five-year allograft survival of 80.8% which is comparable with other studies.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedic Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

ABSTRACT
Reconstructions of large segmental bone defects after resection of bone tumours with massive structural allografts have a high number of reported complications including fracture, infection and non-union. Our goal is to report the survival and complications of massive allografts in our patients. A total of 32 patients were evaluated for fracture, infection, non-union rate and survival of their massive allograft reconstructions. The average follow-up for this group was five years and three months. The total fracture rate was 13% with a total infection rate of 16%. We found a low union rate of 25%. The total survival of the allografts was 80.8% (+/- 18.7%) after five years. We found a five-year allograft survival of 80.8% which is comparable with other studies.

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Related in: MedlinePlus

Fixation of the allograft with the stem of the endoprosthesis, non-union 24 months postoperatively
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Fig1: Fixation of the allograft with the stem of the endoprosthesis, non-union 24 months postoperatively

Mentions: In 18 cases the lesion was close to the joint and the defect was reconstructed with an allograft-prosthesis (Waldemar Link, Hamburg, Germany) composite and included eight knee, six hip and four shoulder prostheses. In these patients the graft was fixed by means of the stem of the endoprosthesis (Fig. 1). An allograft in combination with an arthrodesis nail (Waldemar Link, Hamburg, Germany) was used in three patients after resection of the knee joint including the extensor apparatus. In 11 cases with adequate margins in relation to the joints, fixation of an intercalary allograft was performed with an intramedullary nail and/or plate (Synthes, Philadelphia, PA, USA).Fig. 1


Survival of massive allografts in segmental oncological bone defect reconstructions.

Bullens PH, Minderhoud NM, de Waal Malefijt MC, Veth RP, Buma P, Schreuder HW - Int Orthop (2008)

Fixation of the allograft with the stem of the endoprosthesis, non-union 24 months postoperatively
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2903090&req=5

Fig1: Fixation of the allograft with the stem of the endoprosthesis, non-union 24 months postoperatively
Mentions: In 18 cases the lesion was close to the joint and the defect was reconstructed with an allograft-prosthesis (Waldemar Link, Hamburg, Germany) composite and included eight knee, six hip and four shoulder prostheses. In these patients the graft was fixed by means of the stem of the endoprosthesis (Fig. 1). An allograft in combination with an arthrodesis nail (Waldemar Link, Hamburg, Germany) was used in three patients after resection of the knee joint including the extensor apparatus. In 11 cases with adequate margins in relation to the joints, fixation of an intercalary allograft was performed with an intramedullary nail and/or plate (Synthes, Philadelphia, PA, USA).Fig. 1

Bottom Line: The average follow-up for this group was five years and three months.We found a low union rate of 25%.We found a five-year allograft survival of 80.8% which is comparable with other studies.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedic Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

ABSTRACT
Reconstructions of large segmental bone defects after resection of bone tumours with massive structural allografts have a high number of reported complications including fracture, infection and non-union. Our goal is to report the survival and complications of massive allografts in our patients. A total of 32 patients were evaluated for fracture, infection, non-union rate and survival of their massive allograft reconstructions. The average follow-up for this group was five years and three months. The total fracture rate was 13% with a total infection rate of 16%. We found a low union rate of 25%. The total survival of the allografts was 80.8% (+/- 18.7%) after five years. We found a five-year allograft survival of 80.8% which is comparable with other studies.

Show MeSH
Related in: MedlinePlus