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Ovarian lymphoma.

Crasta JA, Vallikad E - Indian J Med Paediatr Oncol (2009)

Bottom Line: The involvement of the ovary in lymphomatous processes is rare.Such an involvement can occur in 2 ways, either primary or secondary, which usually presents with abdominal or pelvic complaints.We present a case of secondary involvement of the ovary with occult extra-ovarian nodal disease and discuss the histogenesis of ovarian lymphomas with criteria for diagnosis and differential diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, St. John's Medical College, Bangalore, Karnataka, India.

ABSTRACT
The involvement of the ovary in lymphomatous processes is rare. Such an involvement can occur in 2 ways, either primary or secondary, which usually presents with abdominal or pelvic complaints. We present a case of secondary involvement of the ovary with occult extra-ovarian nodal disease and discuss the histogenesis of ovarian lymphomas with criteria for diagnosis and differential diagnosis.

No MeSH data available.


Related in: MedlinePlus

Cells with hyperchromatic nuclei and scant cytoplasm with dispersed large cells (×45)
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Figure 0002: Cells with hyperchromatic nuclei and scant cytoplasm with dispersed large cells (×45)

Mentions: On gross examination, the right ovarian mass measured 8.5 × 6.0 × 3.0 cm with an intact capsule and was solid and grayish white. The omentum and the fibro-adipose tissue from the paracolic gutter were covered by exudates and showed no nodules. Microscopic examination of ovarian mass revealed ovarian tissue was replaced by diffuse sheets of monotonous medium-sized cells, with a few large cells [Figure 1] at foci forming cords and trabeculae. The cells had scant cytoplasm and cleaved nuclei-clumped chromatin with conspicuous nucleoli [Figure 2]. There was increased mitotic activity with many atypical mitoses. Neither follicular structures nor starry-sky pattern was noted. Immunohistochemically, the cells were positive for LCA and negative for cytokeratin, which confirmed the diagnosis of lymphoma. Sections from the omentum and biopsy from the paracolic gutter revealed focal collections of these lymphoid cells with areas of necrosis and acute inflammatory infiltrate. A diagnosis of diffuse non-Hodgkin′s lymphoma (probably diffuse large-cell lymphoma) involving the ovary, omentum and pericolic tissue was rendered.


Ovarian lymphoma.

Crasta JA, Vallikad E - Indian J Med Paediatr Oncol (2009)

Cells with hyperchromatic nuclei and scant cytoplasm with dispersed large cells (×45)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2902212&req=5

Figure 0002: Cells with hyperchromatic nuclei and scant cytoplasm with dispersed large cells (×45)
Mentions: On gross examination, the right ovarian mass measured 8.5 × 6.0 × 3.0 cm with an intact capsule and was solid and grayish white. The omentum and the fibro-adipose tissue from the paracolic gutter were covered by exudates and showed no nodules. Microscopic examination of ovarian mass revealed ovarian tissue was replaced by diffuse sheets of monotonous medium-sized cells, with a few large cells [Figure 1] at foci forming cords and trabeculae. The cells had scant cytoplasm and cleaved nuclei-clumped chromatin with conspicuous nucleoli [Figure 2]. There was increased mitotic activity with many atypical mitoses. Neither follicular structures nor starry-sky pattern was noted. Immunohistochemically, the cells were positive for LCA and negative for cytokeratin, which confirmed the diagnosis of lymphoma. Sections from the omentum and biopsy from the paracolic gutter revealed focal collections of these lymphoid cells with areas of necrosis and acute inflammatory infiltrate. A diagnosis of diffuse non-Hodgkin′s lymphoma (probably diffuse large-cell lymphoma) involving the ovary, omentum and pericolic tissue was rendered.

Bottom Line: The involvement of the ovary in lymphomatous processes is rare.Such an involvement can occur in 2 ways, either primary or secondary, which usually presents with abdominal or pelvic complaints.We present a case of secondary involvement of the ovary with occult extra-ovarian nodal disease and discuss the histogenesis of ovarian lymphomas with criteria for diagnosis and differential diagnosis.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology, St. John's Medical College, Bangalore, Karnataka, India.

ABSTRACT
The involvement of the ovary in lymphomatous processes is rare. Such an involvement can occur in 2 ways, either primary or secondary, which usually presents with abdominal or pelvic complaints. We present a case of secondary involvement of the ovary with occult extra-ovarian nodal disease and discuss the histogenesis of ovarian lymphomas with criteria for diagnosis and differential diagnosis.

No MeSH data available.


Related in: MedlinePlus