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Adrenocortical carcinoma with skeletal metastases in a postmenopausal woman.

Mitra S, Roy SG, Sur PK - Indian J Med Paediatr Oncol (2009)

Bottom Line: In most cases, hormonal investigations reveal an excess secretion of steroids, mostly cortisol and androgens.A 54-year-old lady presented with history of pain in left shoulder and leg for 6 months and features of virilization.The patient has received palliative radiotherapy for the skeletal lesions and 3 cycles of palliative chemotherapy at present.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiotherapy, Medical College Hospital, 88, College Street, Kolkata - 700 073, India.

ABSTRACT
Adrenocortical cancer is a very rare tumor with a poor prognosis. About half of them are hormone-secreting tumors. In most cases, hormonal investigations reveal an excess secretion of steroids, mostly cortisol and androgens. A 54-year-old lady presented with history of pain in left shoulder and leg for 6 months and features of virilization. CT-guided fine-needle aspiration cytology of an abdominal mass revealed the presence of a carcinoma of the left adrenal cortex. A whole-body radionuclide bone scan revealed increased uptake in the left clavicle and left femur. The patient has received palliative radiotherapy for the skeletal lesions and 3 cycles of palliative chemotherapy at present.

No MeSH data available.


Related in: MedlinePlus

The patient with masculine facial features
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Figure 0001: The patient with masculine facial features

Mentions: On examination the patient had features of hirsutism, suggested by facial appearance resembling that of a male with facial hair, with hair also present on her upper limbs and back [Figure 1]. She also had temporal baldness, coarse hands resembling male hands, atrophy of the breasts and clitoromegaly. There was also pitting nontender edema of the left lower limb after an incident of trivial trauma. Examination per abdomen revealed a nontender mass in the left lumbar area and nontender hepatomegaly. Her blood pressure measured on several occasions was not raised.


Adrenocortical carcinoma with skeletal metastases in a postmenopausal woman.

Mitra S, Roy SG, Sur PK - Indian J Med Paediatr Oncol (2009)

The patient with masculine facial features
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC2902211&req=5

Figure 0001: The patient with masculine facial features
Mentions: On examination the patient had features of hirsutism, suggested by facial appearance resembling that of a male with facial hair, with hair also present on her upper limbs and back [Figure 1]. She also had temporal baldness, coarse hands resembling male hands, atrophy of the breasts and clitoromegaly. There was also pitting nontender edema of the left lower limb after an incident of trivial trauma. Examination per abdomen revealed a nontender mass in the left lumbar area and nontender hepatomegaly. Her blood pressure measured on several occasions was not raised.

Bottom Line: In most cases, hormonal investigations reveal an excess secretion of steroids, mostly cortisol and androgens.A 54-year-old lady presented with history of pain in left shoulder and leg for 6 months and features of virilization.The patient has received palliative radiotherapy for the skeletal lesions and 3 cycles of palliative chemotherapy at present.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiotherapy, Medical College Hospital, 88, College Street, Kolkata - 700 073, India.

ABSTRACT
Adrenocortical cancer is a very rare tumor with a poor prognosis. About half of them are hormone-secreting tumors. In most cases, hormonal investigations reveal an excess secretion of steroids, mostly cortisol and androgens. A 54-year-old lady presented with history of pain in left shoulder and leg for 6 months and features of virilization. CT-guided fine-needle aspiration cytology of an abdominal mass revealed the presence of a carcinoma of the left adrenal cortex. A whole-body radionuclide bone scan revealed increased uptake in the left clavicle and left femur. The patient has received palliative radiotherapy for the skeletal lesions and 3 cycles of palliative chemotherapy at present.

No MeSH data available.


Related in: MedlinePlus