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Nasopharyngeal chondrolipoma.

Kinshuck AJ, Agrawal S, Patel VM, Bishop PW, Jones PH - Int J Otolaryngol (2010)

Bottom Line: Lipomas are common soft tissue tumours, although their incidence in the nasopharynx is very low.A rarer variant of lipoma, chondrolipomas are benign mesenchymal tumours.An endonasal approach to excision has not been previously described.

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology and Head & Neck Surgery, University Hospital Aintree, Longmoor Lane, Liverpool L9 7AL, UK.

ABSTRACT
In this case report, we describe the presentation and treatment of a patient with nasopharyngeal chondrolipoma. Lipomas are common soft tissue tumours, although their incidence in the nasopharynx is very low. A rarer variant of lipoma, chondrolipomas are benign mesenchymal tumours. They are formed by the proliferation of mature adipocytes and contain different amounts of mature cartilaginous tissue; Weiss "Enzinger and Weiss's soft tissue tumours", 4th ed: Mosby, St Louis; 2001 This represents the second reported case of a nasopharyngeal chondrolipoma. An endonasal approach to excision has not been previously described.

No MeSH data available.


Related in: MedlinePlus

The images above are both at × 20 magnification. The view in Figure 3(a) shows a predominance of mature adipose tissue with fine bands of fibrosis and round islands of cartilage. The surface ciliated columnar epithelium is to be seen on the right of this image along with an island of cartilage. The chondrocytes lack cytological atypia or mitotic activity. Figure 3(b) shows an island of cartilage at higher power.
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fig3: The images above are both at × 20 magnification. The view in Figure 3(a) shows a predominance of mature adipose tissue with fine bands of fibrosis and round islands of cartilage. The surface ciliated columnar epithelium is to be seen on the right of this image along with an island of cartilage. The chondrocytes lack cytological atypia or mitotic activity. Figure 3(b) shows an island of cartilage at higher power.

Mentions: Microscopically, the mass was covered by a ciliated columnar epithelium showing focal squamous metaplasia. The stroma was composed of fibrous tissue exhibiting myxoid changes and mixed with mature fatty tissue and thin and thick walled blood vessels, some containing thrombi. Islands of cartilaginous tissue were present There were scattered mast cells and perivascular cuffing by lymphocytes and plasma cells. The appearances were concluded to be consistent with a chondrolipoma (Figure 3).


Nasopharyngeal chondrolipoma.

Kinshuck AJ, Agrawal S, Patel VM, Bishop PW, Jones PH - Int J Otolaryngol (2010)

The images above are both at × 20 magnification. The view in Figure 3(a) shows a predominance of mature adipose tissue with fine bands of fibrosis and round islands of cartilage. The surface ciliated columnar epithelium is to be seen on the right of this image along with an island of cartilage. The chondrocytes lack cytological atypia or mitotic activity. Figure 3(b) shows an island of cartilage at higher power.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2902126&req=5

fig3: The images above are both at × 20 magnification. The view in Figure 3(a) shows a predominance of mature adipose tissue with fine bands of fibrosis and round islands of cartilage. The surface ciliated columnar epithelium is to be seen on the right of this image along with an island of cartilage. The chondrocytes lack cytological atypia or mitotic activity. Figure 3(b) shows an island of cartilage at higher power.
Mentions: Microscopically, the mass was covered by a ciliated columnar epithelium showing focal squamous metaplasia. The stroma was composed of fibrous tissue exhibiting myxoid changes and mixed with mature fatty tissue and thin and thick walled blood vessels, some containing thrombi. Islands of cartilaginous tissue were present There were scattered mast cells and perivascular cuffing by lymphocytes and plasma cells. The appearances were concluded to be consistent with a chondrolipoma (Figure 3).

Bottom Line: Lipomas are common soft tissue tumours, although their incidence in the nasopharynx is very low.A rarer variant of lipoma, chondrolipomas are benign mesenchymal tumours.An endonasal approach to excision has not been previously described.

View Article: PubMed Central - PubMed

Affiliation: Department of Otolaryngology and Head & Neck Surgery, University Hospital Aintree, Longmoor Lane, Liverpool L9 7AL, UK.

ABSTRACT
In this case report, we describe the presentation and treatment of a patient with nasopharyngeal chondrolipoma. Lipomas are common soft tissue tumours, although their incidence in the nasopharynx is very low. A rarer variant of lipoma, chondrolipomas are benign mesenchymal tumours. They are formed by the proliferation of mature adipocytes and contain different amounts of mature cartilaginous tissue; Weiss "Enzinger and Weiss's soft tissue tumours", 4th ed: Mosby, St Louis; 2001 This represents the second reported case of a nasopharyngeal chondrolipoma. An endonasal approach to excision has not been previously described.

No MeSH data available.


Related in: MedlinePlus