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Angiosarcoma mimicking rhinophyma.

Lo Presti M, Mazzella C, Monfrecola A, Falleti J - Dermatol Res Pract (2010)

Bottom Line: Routine laboratory analysis was normal.Punch biopsy was performed, and histopathology and immunohistochemical studies were consistent with cutaneous angiosarcoma.This is the report of a face angiosarcoma with an unusual and very deceptive clinical presentation.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology Systematics, Section of Dermatology, University Federico II of Naples, via S. Pansini 5, 80131 Naples, Italy.

ABSTRACT
We report the case of a 61-year-old man showing persistent erythematous macules, plaques, and partially confluent nodules with irregular borders, developed on his nose for one year. During that time the patient underwent several dermatological consultations, and all produced the same diagnosis: rhinophyma. So antibiotic and steroid treatment was carried out without any improvement while the lesions kept growing. When the patient came to our observation, physical examination revealed large, infiltrative, oedematous, erythematous plaques and rare nodules, with superficial telangiectatic vessels. Cervical lymphadenopathy was not detectable. Routine laboratory analysis was normal. Punch biopsy was performed, and histopathology and immunohistochemical studies were consistent with cutaneous angiosarcoma. This is the report of a face angiosarcoma with an unusual and very deceptive clinical presentation.

No MeSH data available.


Related in: MedlinePlus

(a) Neoplastic vascular proliferation lined by atypical and plump endothelial cells in the dermis. (b) Positivity of neoplastic endothelial cells for CD 34.
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fig2: (a) Neoplastic vascular proliferation lined by atypical and plump endothelial cells in the dermis. (b) Positivity of neoplastic endothelial cells for CD 34.

Mentions: Histopathologic examination of skin biopsy, taken from a nodule, showed vascular proliferation lined by atypical and plump endothelial cells in the dermis; immunohistochemistry proved the positivity of neoplastic endothelial cells for CD31 and CD34 (Figures 2(a), 2(b)).


Angiosarcoma mimicking rhinophyma.

Lo Presti M, Mazzella C, Monfrecola A, Falleti J - Dermatol Res Pract (2010)

(a) Neoplastic vascular proliferation lined by atypical and plump endothelial cells in the dermis. (b) Positivity of neoplastic endothelial cells for CD 34.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2902059&req=5

fig2: (a) Neoplastic vascular proliferation lined by atypical and plump endothelial cells in the dermis. (b) Positivity of neoplastic endothelial cells for CD 34.
Mentions: Histopathologic examination of skin biopsy, taken from a nodule, showed vascular proliferation lined by atypical and plump endothelial cells in the dermis; immunohistochemistry proved the positivity of neoplastic endothelial cells for CD31 and CD34 (Figures 2(a), 2(b)).

Bottom Line: Routine laboratory analysis was normal.Punch biopsy was performed, and histopathology and immunohistochemical studies were consistent with cutaneous angiosarcoma.This is the report of a face angiosarcoma with an unusual and very deceptive clinical presentation.

View Article: PubMed Central - PubMed

Affiliation: Department of Pathology Systematics, Section of Dermatology, University Federico II of Naples, via S. Pansini 5, 80131 Naples, Italy.

ABSTRACT
We report the case of a 61-year-old man showing persistent erythematous macules, plaques, and partially confluent nodules with irregular borders, developed on his nose for one year. During that time the patient underwent several dermatological consultations, and all produced the same diagnosis: rhinophyma. So antibiotic and steroid treatment was carried out without any improvement while the lesions kept growing. When the patient came to our observation, physical examination revealed large, infiltrative, oedematous, erythematous plaques and rare nodules, with superficial telangiectatic vessels. Cervical lymphadenopathy was not detectable. Routine laboratory analysis was normal. Punch biopsy was performed, and histopathology and immunohistochemical studies were consistent with cutaneous angiosarcoma. This is the report of a face angiosarcoma with an unusual and very deceptive clinical presentation.

No MeSH data available.


Related in: MedlinePlus