Limits...
Eosinophilic panniculitis and insect bite-like eruption in a patient with chronic lymphocytic leukaemia: a spectrum of the same entity.

Rodríguez-Lojo R, Almagro M, Piñeyro F, Pérez-Varela L, Fernández-Jorge B, Del Pozo J, Sacristán F, Fonseca E - Dermatol Res Pract (2010)

Bottom Line: Background.The cutaneous eruptions began as eosinophilic panniculitis and after changed to insect bite-like lesions.Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Complexo Hospitalario Universitario A Coruña, 15006 A Coruña, Spain.

ABSTRACT
Background. Eosinophilic dermatosis of hematologic disorders is a reactive process that may cause a variety of clinical manifestations. Methods. We report a patient who had outbreaks of skin lesions since the onset of chronic lymphocytic leukaemia. Results. The cutaneous eruptions began as eosinophilic panniculitis and after changed to insect bite-like lesions. Conclusion. We think that eosinophilic panniculitis and insect bite-like lesions may be part of the spectrum of the same entity in patients with hematologic disorders.

No MeSH data available.


Related in: MedlinePlus

(a) Prurigo-like lesions with central crust mimicking arthropod bites. (b) Interstitial dermal infiltration composed by eosinophils. (c) Flame figures.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC2901615&req=5

fig2: (a) Prurigo-like lesions with central crust mimicking arthropod bites. (b) Interstitial dermal infiltration composed by eosinophils. (c) Flame figures.

Mentions: During successive outbreaks the lesions changed their morphology to urticarial, prurigo-like lesions resembling insect bites. Examination of skin revealed a widespread eruption consisting of erythematous papules, some with central crust and excoriations (Figure 2(a)). He denied history of arthropod assaults. A skin biopsy specimen showed a dense eosinophilic interstitial infiltrate that affected dermis (Figure 2(b)) with occasional “flame figures” (Figure 2(c)), and no changes in subcutaneous tissue were observed. The patient was diagnosed of insect bite-like reaction related to CLL. Skin lesions had a good response to topical and systemic steroid treatment, and recurrences were reduced with dapsone (150 mg daily). Cutaneous eruptions fully resolved when leukaemia was controlled.


Eosinophilic panniculitis and insect bite-like eruption in a patient with chronic lymphocytic leukaemia: a spectrum of the same entity.

Rodríguez-Lojo R, Almagro M, Piñeyro F, Pérez-Varela L, Fernández-Jorge B, Del Pozo J, Sacristán F, Fonseca E - Dermatol Res Pract (2010)

(a) Prurigo-like lesions with central crust mimicking arthropod bites. (b) Interstitial dermal infiltration composed by eosinophils. (c) Flame figures.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2901615&req=5

fig2: (a) Prurigo-like lesions with central crust mimicking arthropod bites. (b) Interstitial dermal infiltration composed by eosinophils. (c) Flame figures.
Mentions: During successive outbreaks the lesions changed their morphology to urticarial, prurigo-like lesions resembling insect bites. Examination of skin revealed a widespread eruption consisting of erythematous papules, some with central crust and excoriations (Figure 2(a)). He denied history of arthropod assaults. A skin biopsy specimen showed a dense eosinophilic interstitial infiltrate that affected dermis (Figure 2(b)) with occasional “flame figures” (Figure 2(c)), and no changes in subcutaneous tissue were observed. The patient was diagnosed of insect bite-like reaction related to CLL. Skin lesions had a good response to topical and systemic steroid treatment, and recurrences were reduced with dapsone (150 mg daily). Cutaneous eruptions fully resolved when leukaemia was controlled.

Bottom Line: Background.The cutaneous eruptions began as eosinophilic panniculitis and after changed to insect bite-like lesions.Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Complexo Hospitalario Universitario A Coruña, 15006 A Coruña, Spain.

ABSTRACT
Background. Eosinophilic dermatosis of hematologic disorders is a reactive process that may cause a variety of clinical manifestations. Methods. We report a patient who had outbreaks of skin lesions since the onset of chronic lymphocytic leukaemia. Results. The cutaneous eruptions began as eosinophilic panniculitis and after changed to insect bite-like lesions. Conclusion. We think that eosinophilic panniculitis and insect bite-like lesions may be part of the spectrum of the same entity in patients with hematologic disorders.

No MeSH data available.


Related in: MedlinePlus