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Eosinophilic panniculitis and insect bite-like eruption in a patient with chronic lymphocytic leukaemia: a spectrum of the same entity.

Rodríguez-Lojo R, Almagro M, Piñeyro F, Pérez-Varela L, Fernández-Jorge B, Del Pozo J, Sacristán F, Fonseca E - Dermatol Res Pract (2010)

Bottom Line: Background.The cutaneous eruptions began as eosinophilic panniculitis and after changed to insect bite-like lesions.Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Complexo Hospitalario Universitario A Coruña, 15006 A Coruña, Spain.

ABSTRACT
Background. Eosinophilic dermatosis of hematologic disorders is a reactive process that may cause a variety of clinical manifestations. Methods. We report a patient who had outbreaks of skin lesions since the onset of chronic lymphocytic leukaemia. Results. The cutaneous eruptions began as eosinophilic panniculitis and after changed to insect bite-like lesions. Conclusion. We think that eosinophilic panniculitis and insect bite-like lesions may be part of the spectrum of the same entity in patients with hematologic disorders.

No MeSH data available.


Related in: MedlinePlus

(a) Inflammatory nodules on thighs. (b) Panniculitis with eosinophils infiltration.
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fig1: (a) Inflammatory nodules on thighs. (b) Panniculitis with eosinophils infiltration.

Mentions: A 63-year-old man was diagnosed of chronic lymphoproliferative syndrome in 2006, classified as chronic lymphocytic leukaemia (CLL) of B cells and treated with chlorambucil for 9 months; fludarabine for 4 months; cyclophosphamide, vincristine, prednisone, and rituximab (CVP-R) for 3 months; cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) for 6 months. In November 2007, he consulted for a 1-year history of recurrent, painful nodules with inflammatory signs on his limbs and trunk (Figure 1(a)). This skin eruption had appeared since onset of the CLL and cutaneous lesions sometimes worsened after chemotherapy cycles. Individual lesions showed a typical course of one-week duration and spontaneous resolution without scar formation. There were not constitutional symptoms or mucosal lesions.


Eosinophilic panniculitis and insect bite-like eruption in a patient with chronic lymphocytic leukaemia: a spectrum of the same entity.

Rodríguez-Lojo R, Almagro M, Piñeyro F, Pérez-Varela L, Fernández-Jorge B, Del Pozo J, Sacristán F, Fonseca E - Dermatol Res Pract (2010)

(a) Inflammatory nodules on thighs. (b) Panniculitis with eosinophils infiltration.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC2901615&req=5

fig1: (a) Inflammatory nodules on thighs. (b) Panniculitis with eosinophils infiltration.
Mentions: A 63-year-old man was diagnosed of chronic lymphoproliferative syndrome in 2006, classified as chronic lymphocytic leukaemia (CLL) of B cells and treated with chlorambucil for 9 months; fludarabine for 4 months; cyclophosphamide, vincristine, prednisone, and rituximab (CVP-R) for 3 months; cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) for 6 months. In November 2007, he consulted for a 1-year history of recurrent, painful nodules with inflammatory signs on his limbs and trunk (Figure 1(a)). This skin eruption had appeared since onset of the CLL and cutaneous lesions sometimes worsened after chemotherapy cycles. Individual lesions showed a typical course of one-week duration and spontaneous resolution without scar formation. There were not constitutional symptoms or mucosal lesions.

Bottom Line: Background.The cutaneous eruptions began as eosinophilic panniculitis and after changed to insect bite-like lesions.Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Complexo Hospitalario Universitario A Coruña, 15006 A Coruña, Spain.

ABSTRACT
Background. Eosinophilic dermatosis of hematologic disorders is a reactive process that may cause a variety of clinical manifestations. Methods. We report a patient who had outbreaks of skin lesions since the onset of chronic lymphocytic leukaemia. Results. The cutaneous eruptions began as eosinophilic panniculitis and after changed to insect bite-like lesions. Conclusion. We think that eosinophilic panniculitis and insect bite-like lesions may be part of the spectrum of the same entity in patients with hematologic disorders.

No MeSH data available.


Related in: MedlinePlus